Publications by authors named "Ryan C Winger"

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Persistent Classical and Atypical Memory B Cells Underlie Heterogeneous Vaccine Responses in Ocrelizumab-Treated Multiple Sclerosis.
Ryan Curtin, Yogambigai Velmurugu, Fatoumatta Dibba, Yuan Hao, Chaitra Sreenivasaiah, Ryan C Winger

bioRxiv· November 2025

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Multi-Omic characterization of the effects of Ocrelizumab in patients with relapsing-remitting multiple sclerosis.
Sergey A Kornilov, Nathan D Price, Richard Gelinas, Juan Acosta, Mary E Brunkow, Ryan C Winger

J Neurol Sci· December 2024

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Longitudinal study of immunity to SARS-CoV2 in ocrelizumab-treated MS patients up to 2 years after COVID-19 vaccination.
Ilya Kister, Ryan Curtin, Amanda L Piquet, Tyler Borko, Jinglan Pei, Ryan C Winger

Ann Clin Transl Neurol· July 2024

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Evolution of atrophied T2 lesion volume in primary-progressive multiple sclerosis: results from the phase 3 ORATORIO study.
Robert Zivadinov, Jinglan Pei, David Clayton, Donna E Goldman, Ryan C Winger

J Neurol Neurosurg Psychiatry· May 2024

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Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis.
Anne H Cross, Jeffrey M Gelfand, Simon Thebault, Jeffrey L Bennett, H Christian von Büdingen, Ryan C Winger

JAMA Neurol· March 2024

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Development of an LC-MS/MS Method to Measure Sphingolipids in CSF from Patients with Multiple Sclerosis.
Yadira X Perez-Paramo, Dawn Dufield, Rathna Veeramachaneni, Emily Parkhurst, Christopher Harp, Ryan C Winger

Mol Pharmacol· February 2024

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Safety and patient experience with at-home infusion of ocrelizumab for multiple sclerosis.
Britney Barrera, Haley Simpson, Eric Engebretson, Stefan Sillau, Brooke Valdez, Ryan C Winger

Ann Clin Transl Neurol· April 2023

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Differential effects of anti-CD20 therapy on CD4 and CD8 T cells and implication of CD20-expressing CD8 T cells in MS disease activity.
Koji Shinoda, Rui Li, Ayman Rezk, Ina Mexhitaj, Kristina R Patterson, Ryan C Winger

Proc Natl Acad Sci U S A· January 2023

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The CELLO trial: Protocol of a planned phase 4 study to assess the efficacy of Ocrelizumab in patients with radiologically isolated syndrome.
Erin E Longbrake, Le H Hua, Ellen M Mowry, Susan A Gauthier, Enrique Alvarez, Ryan C Winger

Mult Scler Relat Disord· December 2022

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Hybrid and vaccine-induced immunity against SAR-CoV-2 in MS patients on different disease-modifying therapies.
Ilya Kister, Ryan Curtin, Jinglan Pei, Katherine Perdomo, Tamar E Bacon, Ryan C Winger

Ann Clin Transl Neurol· October 2022

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Cellular and Humoral Immunity to SARS-CoV-2 Infection in Multiple Sclerosis Patients on Ocrelizumab and Other Disease-Modifying Therapies: A Multi-Ethnic Observational Study.
Ilya Kister, Yury Patskovsky, Ryan Curtin, Jinglan Pei, Katherine Perdomo, Ryan C Winger

Ann Neurol· June 2022

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The FLUENT study design: investigating immune cell subset and neurofilament changes in patients with relapsing multiple sclerosis treated with fingolimod.
Jeffrey A Cohen, Amit Bar-Or, Bruce A C Cree, Yang Mao-Draayer, May H Han, Ryan C Winger

Mult Scler J Exp Transl Clin· January 2019

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Tolerance checkpoint bypass permits emergence of pathogenic T cells to neuromyelitis optica autoantigen aquaporin-4.
Sharon A Sagan, Ryan C Winger, Andrés Cruz-Herranz, Patricia A Nelson, Sarah Hagberg

Proc Natl Acad Sci U S A· December 2016

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Your nose knows how to target brain inflammation.
Ryan C Winger, Scott S Zamvil

Brain· July 2016

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Antibodies in multiple sclerosis oligoclonal bands target debris.
Ryan C Winger, Scott S Zamvil

Proc Natl Acad Sci U S A· July 2016

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CNS accumulation of regulatory B cells is VLA-4-dependent.
Klaus Lehmann-Horn, Sharon A Sagan, Ryan C Winger, Collin M Spencer, Claude C A Bernard

Neurol Neuroimmunol Neuroinflamm· April 2016

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Cutting Edge: CD99 Is a Novel Therapeutic Target for Control of T Cell-Mediated Central Nervous System Autoimmune Disease.
Ryan C Winger, Christopher T Harp, Ming-Yi Chiang, David P Sullivan, Richard L Watson

J Immunol· February 2016

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Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
Richard L Watson, Jochen Buck, Lonny R Levin, Ryan C Winger, Jing Wang

J Exp Med· June 2015

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Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier.
Ryan C Winger, Jennifer E Koblinski, Takashi Kanda, Richard M Ransohoff, William A Muller

J Immunol· September 2014

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TGF-β signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE.
David J Huss, Ryan C Winger, Gina Mavrikis Cox, Mireia Guerau-de-Arellano, Yuhong Yang

Eur J Immunol· October 2011

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TGF-beta enhances effector Th1 cell activation but promotes self-regulation via IL-10.
David J Huss, Ryan C Winger, Haiyan Peng, Yuhong Yang, Michael K Racke

J Immunol· May 2010

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