Publications by authors named "Ryan D Chow"

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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner.
Madison S Strine, Wesley L Cai, Jin Wei, Mia Madel Alfajaro, Renata B Filler, Scott B Biering, Sylvia Sarnik, Ryan D Chow, Ajinkya Patil, Kasey S Cervantes

PLoS Biol· June 2023

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Non-steroidal anti-inflammatory drugs dampen the cytokine and antibody response to SARS-CoV-2 infection.
Jennifer S Chen, Mia Madel Alfajaro, Ryan D Chow, Jin Wei, Renata B Filler, Stephanie C Eisenbarth, Craig B Wilen

J Virol· March 2021

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Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy.
Feifei Zhang, Ryan D Chow, Emily He, Chuanpeng Dong, Shan Xin

Nat Biotechnol· December 2025

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Author Correction: Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy.
Feifei Zhang, Ryan D Chow, Emily He, Chuanpeng Dong, Shan Xin

Nat Biotechnol· December 2025

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Association Between Early on-Treatment Weight Loss With Enfortumab Vedotin Plus Pembrolizumab and Survival in Advanced Urothelial Carcinoma.
Ryan D Chow, Ronac Mamtani

Clin Genitourin Cancer· December 2025

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Reduced-Dose Enfortumab Vedotin, Treatment Continuity, and Survival in Urothelial Cancer.
Ryan D Chow, Ramy Sedhom, Ronac Mamtani

JAMA Oncol· November 2025

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Outcomes of enfortumab vedotin plus pembrolizumab in patients with advanced urothelial cancer and severe renal dysfunction.
Henry K Litt, Ronac Mamtani, Ryan D Chow

Urol Oncol· November 2025

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Assessment of synergistic vs. independent drug activity for enfortumab vedotin and pembrolizumab in untreated advanced urothelial carcinoma.
Ryan D Chow, Ronac Mamtani

Urol Oncol· October 2025

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Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering.
Kaiyuan Tang, Liqun Zhou, Xiaolong Tian, Shao-Yu Fang, Erica Vandenbulcke, Ryan D Chow

Nat Biomed Eng· August 2025

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In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy.
Lei Peng, Paul A Renauer, Giacomo Sferruzza, Luojia Yang, Yongji Zou, Ryan D Chow

Nat Biotechnol· May 2025

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Persistent postremission clonal hematopoiesis shapes the relapse trajectories of acute myeloid leukemia.
Ryan D Chow, Priya Velu, Safoora Deihimi, Jonathan Belman, Angela Youn

Blood Adv· April 2025

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Phenotypic evaluation of deep learning models for classifying germline variant pathogenicity.
Ryan D Chow, Katherine L Nathanson, Ravi B Parikh

NPJ Precis Oncol· October 2024

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Early drivers of clonal hematopoiesis shape the evolutionary trajectories of acute myeloid leukemia.
Ryan D Chow, Priya Velu, Safoora Deihimi, Jonathan Belman, Angela Youn

medRxiv· September 2024

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Real-world evaluation of deep learning algorithms to classify functional pathogenic germline variants.
Ryan D Chow, Ravi B Parikh, Katherine L Nathanson

medRxiv· April 2024

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Massively parallel knock-in engineering of human T cells.
Xiaoyun Dai, Jonathan J Park, Yaying Du, Zhenkun Na, Stanley Z Lam, Ryan D Chow

Nat Biotechnol· September 2023

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CTLA-4 tail fusion enhances CAR-T antitumor immunity.
Xiaoyu Zhou, Hanbing Cao, Shao-Yu Fang, Ryan D Chow, Kaiyuan Tang

Nat Immunol· September 2023

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mRNA Staining Distinguishes Palmoplantar Psoriasis from Hyperkeratotic Palmoplantar Eczema in Diagnostic Skin Biopsies.
Jennifer S Chen, Michael J Murphy, Katelyn Singh, Alice Wang, Ryan D Chow

JID Innov· July 2023

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Disparities in immune and targeted therapy utilization for older US patients with metastatic renal cell carcinoma.
Ryan D Chow, Jessica B Long, Sirad Hassan, Stephanie B Wheeler, Lisa P Spees

JNCI Cancer Spectr· May 2023

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Mutations in IFN-γ signaling genes sensitize tumors to immune checkpoint blockade.
Eric Song, Ryan D Chow

Cancer Cell· April 2023

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Perturbomics of tumor-infiltrating NK cells.
Lei Peng, Paul A Renauer, Lupeng Ye, Luojia Yang, Jonathan J Park, Ryan D Chow

bioRxiv· March 2023

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CTLA-4 tail fusion enhances CAR-T anti-tumor immunity.
Xiaoyu Zhou, Hanbing Cao, Shao-Yu Fang, Ryan D Chow, Kaiyuan Tang

bioRxiv· March 2023

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Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering.
Matthew B Dong, Kaiyuan Tang, Xiaoyu Zhou, Johanna Shen, Krista Chen, Ryan D Chow

bioRxiv· March 2023

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Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma.
Ryan D Chow, Tai Michaels, Stefania Bellone, Tobias M P Hartwich, Elena Bonazzoli

Cancer Discov· February 2023

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LRRC15 inhibits SARS-CoV-2 cellular entry in trans.
Jaewon Song, Ryan D Chow, Mario A Peña-Hernández, Li Zhang, Skylar A Loeb

PLoS Biol· October 2022

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Comparison of Cancer-Related Spending and Mortality Rates in the US vs 21 High-Income Countries.
Ryan D Chow, Elizabeth H Bradley, Cary P Gross

JAMA Health Forum· May 2022

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Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.
Lei Peng, Yingxia Hu, Madeleine C Mankowski, Ping Ren, Rita E Chen, Ryan D Chow

Nat Commun· March 2022

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