Publications by authors named "Ryan D Ferrao"

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Discovery of Bis-Acyl Hydrazides as Potent and Bioavailable MTA-Cooperative PRMT5 Inhibitors: A Case Study of Leveraging the Deuterium Kinetic Isotope Effect.
Laurent Debien, Megan K Armstrong, Joshua D Farr, Ryan D Ferrao, Pancham Lal Gupta

J Med Chem· December 2025

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Discovery of Lenacapavir: First-in-Class Twice-Yearly Capsid Inhibitor for HIV-1 Treatment and Pre-exposure Prophylaxis.
Eda Canales, Winston Tse, Scott D Schroeder, Chien-Hung Chou, Qi Liu, Ryan D Ferrao

J Med Chem· October 2025

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Discovery of Edecesertib (GS-5718): A Potent, Selective Inhibitor of IRAK4.
Stephen E Ammann, Jeromy J Cottell, Nathan E Wright, Matthew R Warr, Chelsea A Snyder, Ryan D Ferrao

J Med Chem· June 2025

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Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation.
Ryan D Ferrao, Heidi Ja Wallweber, Patrick J Lupardus

Elife· July 2018

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