Publications by authors named "Ryan D Wuebbles"

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Spatial proteomics reveals recombinant human laminin-111 restores adhesion signaling to laminin-α2-deficient muscle.
Hailey J Hermann, Ryan D Wuebbles, Marisela Dagda, Axel Muñoz, Lauren L Parker

JCI Insight· November 2025

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A gene therapy approach for the treatment of limb-girdle muscular dystrophy 2C/R5.
Hailey Hermann, Ryan D Wuebbles, Dean J Burkin

Mol Ther Methods Clin Dev· June 2023

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Transgenic overexpression of α7 integrin in smooth muscle attenuates allergen-induced airway inflammation in a murine model of asthma.
Mariam A Ba, Annemarie Aiyuk, Karla Hernández, Jon M Evasovic, Ryan D Wuebbles

FASEB Bioadv· November 2022

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Tetrahydrobiopterin shifts the balance from oxidative stress to NO signalling in Duchenne muscular dystrophy.
Ryan D Wuebbles, Ariany Oliveira-Santos, Dean J Burkin

Acta Physiol (Oxf)· July 2021

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A retooled drug that restores ionic balance and cardiac function in dystrophin deficient hearts.
Ryan D Wuebbles, Dean J Burkin

Int J Cardiol· November 2020

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Transgenic mice expressing tunable levels of DUX4 develop characteristic facioscapulohumeral muscular dystrophy-like pathophysiology ranging in severity.
Takako I Jones, Guo-Liang Chew, Pamela Barraza-Flores, Spencer Schreier, Monique Ramirez, Ryan D Wuebbles

Skelet Muscle· April 2020

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Laminin-111 protein therapy enhances muscle regeneration and repair in the GRMD dog model of Duchenne muscular dystrophy.
Pamela Barraza-Flores, Tatiana M Fontelonga, Ryan D Wuebbles, Hailey J Hermann, Andreia M Nunes

Hum Mol Genet· August 2019

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Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.
Tatiana M Fontelonga, Brennan Jordan, Andreia M Nunes, Pamela Barraza-Flores, Nicholas Bolden, Ryan D Wuebbles

Hum Mol Genet· July 2019

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Human Galectin-1 Improves Sarcolemma Stability and Muscle Vascularization in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Ryan D Wuebbles, Vivian Cruz, Pam Van Ry, Pamela Barraza-Flores, Paul D Brewer

Mol Ther Methods Clin Dev· June 2019

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Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.
Andreia M Nunes, Ryan D Wuebbles, Apurva Sarathy, Tatiana M Fontelonga, Marianne Deries

Hum Mol Genet· June 2017

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SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Apurva Sarathy, Ryan D Wuebbles, Tatiana M Fontelonga, Ashley R Tarchione, Lesley A Mathews Griner

Mol Ther· June 2017

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Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy.
Pam M Van Ry, Ryan D Wuebbles, Megan Key, Dean J Burkin

Mol Ther· August 2015

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Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy.
Ryan D Wuebbles, Apurva Sarathy, Joe N Kornegay, Dean J Burkin

Dis Model Mech· September 2013

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A molecular bandage for diseased muscle.
Dean J Burkin, Ryan D Wuebbles

Sci Transl Med· June 2012

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Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophy.
Jachinta E Rooney, Jolie R Knapp, Bradley L Hodges, Ryan D Wuebbles, Dean J Burkin

Am J Pathol· April 2012

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Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.
Jinger A Doe, Ryan D Wuebbles, Erika T Allred, Jachinta E Rooney, Margaret Elorza

J Cell Sci· July 2011

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Testing the effects of FSHD candidate gene expression in vertebrate muscle development.
Ryan D Wuebbles, Steven W Long, Meredith L Hanel, Peter L Jones

Int J Clin Exp Pathol· March 2010

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FSHD region gene 1 (FRG1) is crucial for angiogenesis linking FRG1 to facioscapulohumeral muscular dystrophy-associated vasculopathy.
Ryan D Wuebbles, Meredith L Hanel, Peter L Jones

Dis Model Mech· July 2009

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Muscular dystrophy candidate gene FRG1 is critical for muscle development.
Meredith L Hanel, Ryan D Wuebbles, Peter L Jones

Dev Dyn· June 2009

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