Publications by authors named "Ryan E Tyler"

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The persistent effects of exposure to a predator odor stressor on sensitivity to alcohol.
Ryan E Tyler, Maya N Bluitt, Kalynn J Van Voorhies, Wen Liu, Sarah N Magee

Addict Neurosci· December 2025

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Pharmacokinetic and pharmacodynamic results from a randomized controlled study with the GHSR blocker PF-5190457 in recently abstinent patients with alcohol use disorder.
Ryan E Tyler, Rabea K Pfaff, R M Naseer Khan, Anna Loften, Ryan Zurick

Int J Neuropsychopharmacol· December 2025

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An exploratory analysis of the relationship between ultraprocessed food consumption, alcohol intake, body composition, and cardiometabolic markers in individuals with alcohol use disorder.
Jennifer J Barb, Lillian C King, Shanna Yang, Sara Turner, Carlotta Vizioli, Ryan E Tyler

Alcohol Clin Exp Res (Hoboken)· October 2025

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Circulating Immune and Endocrine Markers in Currently Drinking and Abstinent Individuals With Alcohol Use Disorder and Controls.
Ryan E Tyler, Carlotta Vizioli, Jennifer J Barb, Mehdi Farokhnia, Lorenzo Leggio

Addict Biol· May 2025

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Biased allosteric modulator of neurotensin receptor 1 reduces ethanol drinking and responses to ethanol administration in rodents.
Graydon B Gereau, Diana Zhou, Kalynn Van Voorhies, Ryan E Tyler, Jeffrey Campbell

Addict Neurosci· December 2024

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The persistent effects of predator odor stressor enhance interoceptive sensitivity to alcohol through GABA receptor adaptations in the prelimbic cortex in male, but not female rats.
Ryan E Tyler, Maya N Bluitt, Kalynn J Van Voorhies, Wen Liu, Sarah N Magee

bioRxiv· October 2024

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The crosstalk between fibroblast growth factor 21 (FGF21) system and substance use.
Tammy Wang, Ryan E Tyler, Oyenike Ilaka, Diane Cooper, Mehdi Farokhnia

iScience· July 2024

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mGlu and mGlu receptor negative allosteric modulators attenuate the interoceptive effects of alcohol in male and female rats.
Ryan E Tyler, Kalynn Van Voorhies, Bruce E Blough, Antonio Landavazo, Joyce Besheer

Pharmacol Biochem Behav· June 2024

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Biological basis of addiction and alcohol use disorder.
Ryan E Tyler, Lorenzo Leggio

Clin Liver Dis (Hoboken)· May 2024

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β-arrestin-biased Allosteric Modulator of Neurotensin Receptor 1 Reduces Ethanol Drinking and Responses to Ethanol Administration in Rodents.
Graydon B Gereau, Diana Zhou, Kalynn Van Voorhies, Ryan E Tyler, Jeffrey Campbell

bioRxiv· April 2024

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Deleterious Interaction between the Neurosteroid (3α,5α)3-Hydroxypregnan-20-One (3α,5α-THP) and the Mu-Opioid System Activation during Forced Swim Stress in Rats.
Giorgia Boero, Minna H McFarland, Ryan E Tyler, Todd K O'Buckley, Samantha L Chéry

Biomolecules· August 2023

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Predator odor (TMT) exposure potentiates interoceptive sensitivity to alcohol and increases GABAergic gene expression in the anterior insular cortex and nucleus accumbens in male rats.
Ryan E Tyler, Maya N Bluitt, Kalynn Van Voorhies, Laura C Ornelas, Benjamin Z S Weinberg

Alcohol· November 2022

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High frequency of anti-DSG 2 antibodies in post COVID-19 serum samples.
Edward C Y Lee, Ryan E Tyler, Derrick Johnson, Natalie Koh, Biauw Chi Ong

J Mol Cell Cardiol· September 2022

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Advances in translating mGlu and mGlu receptor selective allosteric modulators as breakthrough treatments for affective disorders and alcohol use disorder.
Ryan E Tyler, Joyce Besheer, Max E Joffe

Pharmacol Biochem Behav· September 2022

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(3α,5α)3-Hydroxypregnan-20-one (3α,5α-THP) Regulation of the HPA Axis in the Context of Different Stressors and Sex.
Giorgia Boero, Ryan E Tyler, Todd K O'Buckley, Irina Balan, Joyce Besheer

Biomolecules· August 2022

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The effects of predator odor (TMT) exposure and mGlu NAM pretreatment on behavioral and NMDA receptor adaptations in the brain.
Ryan E Tyler, Maya N Bluitt, Julie L Engers, Craig W Lindsley, Joyce Besheer

Neuropharmacology· April 2022

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Interoception and alcohol: Mechanisms, networks, and implications.
Dennis F Lovelock, Ryan E Tyler, Joyce Besheer

Neuropharmacology· December 2021

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Increased alcohol self-administration following exposure to the predator odor TMT in active coping female rats.
Laura C Ornelas, Ryan E Tyler, Preethi Irukulapati, Sudheesha Paladugu, Joyce Besheer

Behav Brain Res· March 2021

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(3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) regulation of hypothalamic and extrahypothalamic corticotropin releasing factor (CRF): Sexual dimorphism and brain region specificity in Sprague Dawley rats.
Giorgia Boero, Ryan E Tyler, Caroline A Todd, Todd K O'Buckley, Irina Balan

Neuropharmacology· March 2021

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Exposure to the predator odor TMT induces early and late differential gene expression related to stress and excitatory synaptic function throughout the brain in male rats.
Ryan E Tyler, Benjamin Z S Weinberg, Dennis F Lovelock, Laura C Ornelas, Joyce Besheer

Genes Brain Behav· November 2020

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Detecting neuroinflammation in the brain following chronic alcohol exposure in rats: A comparison between in vivo and in vitro TSPO radioligand binding.
Ryan E Tyler, Sung Won Kim, Min Guo, Yeon Joo Jang, Ruslan Damadzic, Tyler Stodden

Eur J Neurosci· July 2019

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Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.
Ryan E Tyler, Margaret M P Pearce, Thomas A Shaler, James A Olzmann, Ethan J Greenblatt

Mol Biol Cell· December 2012

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Defining human ERAD networks through an integrative mapping strategy.
John C Christianson, James A Olzmann, Thomas A Shaler, Mathew E Sowa, Eric J Bennett, Ryan E Tyler

Nat Cell Biol· November 2011

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OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.
John C Christianson, Thomas A Shaler, Ryan E Tyler, Ron R Kopito

Nat Cell Biol· March 2008

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Ternary complex formation on the adenovirus packaging sequence by the IVa2 and L4 22-kilodalton proteins.
Sean G Ewing, Serena A Byrd, Joan B Christensen, Ryan E Tyler, Michael J Imperiale

J Virol· November 2007

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