Publications by authors named "Ryan Funk"

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Plasma metabolic profiling identifies elevated hippurate as a potential biomarker of methotrexate non-response in juvenile idiopathic arthritis.
Amar Kumar, Mara L Becker, Ryan S Funk

Biomed Pharmacother· December 2025

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Association of Pharmacologic Markers of Anti-Tumor Necrosis Factor-α Activity and Etanercept Effectiveness in Juvenile Idiopathic Arthritis.
Mudassar I Arain, Kishore Polireddy, Eduardo S Fricovsky, Mara L Becker, Mohsin Kazi, Ryan S Funk

Pharmacol Res Perspect· October 2025

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Identification of Plasma Metabolomic Biomarkers of Juvenile Idiopathic Arthritis.
Amar Kumar, Joshua Tatarian, Valentina Shakhnovich, Rachel L Chevalier, Marc Sudman, Ryan S Funk

Metabolites· September 2024

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Plasma metabolomic profiling as a tool to identify predictive biomarkers of methotrexate efficacy in rheumatoid arthritis.
Matthew R Medcalf, Leonidas E Bantis, Peng Shi, Pooja Bhadbhade, Rebekah L Gundry, Ryan S Funk

Semin Arthritis Rheum· October 2022

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Evaluating the impact of a flipped classroom model based on cognitive science of learning strategies in a pharmacotherapy course.
Tiffany R Shin, Crystal Burkhardt, Robyn Kelton, Ashley N Crowl, Ryan S Funk

Curr Pharm Teach Learn· July 2022

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A population physiologically-based pharmacokinetic model to characterize antibody disposition in pediatrics and evaluation of the model using infliximab.
Hsuan Ping Chang, Valentina Shakhnovich, Adam Frymoyer, Ryan Sol Funk, Mara L Becker

Br J Clin Pharmacol· January 2022

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Metabolomic Profiling Identifies Exogenous and Microbiota-Derived Metabolites as Markers of Methotrexate Efficacy in Juvenile Idiopathic Arthritis.
Ryan Sol Funk, Mara L Becker

Front Pharmacol· December 2021

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Methotrexate Disposition, Anti-Folate Activity, and Metabolomic Profiling to Identify Molecular Markers of Disease Activity and Drug Response in the Collagen-Induced Arthritis Mouse Model.
Yezan M Salamoun, Kishore Polireddy, Yu Kyoung Cho, Matthew R Medcalf, Ryan S Funk

Metabolites· December 2021

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Dose-dependent Pharmacological Response to Rituximab in the Treatment of Antineutrophil Cytoplasmic Antibody-associated Vasculitis.
Jason M Springer, Ryan S Funk

J Rheumatol· November 2021

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Low Etanercept Concentrations in Children With Obesity and Juvenile Idiopathic Arthritis.
Stephen J Balevic, Mara L Becker, Daniel Gonzalez, Ryan S Funk

J Pediatr Pharmacol Ther· November 2021

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Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy.
Matthew R Medcalf, Pooja Bhadbhade, Ted R Mikuls, James R O'Dell, Rebekah L Gundry, Ryan S Funk

Metabolites· November 2021

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Defining a Therapeutic Window for Rituximab Maintenance Therapy in ANCA-Associated Vasculitis: A Longitudinal Observational Study.
Jason Michael Springer, Ryan S Funk

J Clin Rheumatol· August 2021

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Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker-driven precision dosing.
Akinyemi Oni-Orisan, Nithya Srinivas, Krina Mehta, Jesmin Lohy Das, Thu T Nguyen, Ryan S Funk

Clin Transl Sci· May 2021

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Factors associated with reduced infliximab exposure in the treatment of pediatric autoimmune disorders: a cross-sectional prospective convenience sampling study.
Ryan S Funk, Valentina Shakhnovich, Yu Kyoung Cho, Kishore Polireddy, Taina Jausurawong

Pediatr Rheumatol Online J· May 2021

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Potential Role of Methotrexate Polyglutamates in Therapeutic Drug Monitoring for Pediatric Inflammatory Bowel Disease.
Ryan Morrow, Ryan Funk, Mara Becker, Ashley Sherman, Leon Van Haandel

Pharmaceuticals (Basel)· May 2021

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Facing Real-World Challenges of Immunogenicity in Pediatric Inflammatory Bowel Disease.
Kyle Gress, Julie A Bass, Ryan S Funk, Ryan P Morrow, Rachel Hasenkamp

Front Immunol· April 2021

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Electrocardiogram-Gated Computed Tomography with Coronary Angiography for Cardiac Substructure Delineation and Sparing in Patients with Mediastinal Lymphomas Treated with Radiation Therapy.
Scott C Lester, Kekoa Taparra, Molly M Petersen, Ryan K Funk, Miran J Blanchard

Pract Radiat Oncol· October 2020

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Reducing Heart Dose with Protons and Cardiac Substructure Sparing for Mediastinal Lymphoma Treatment.
Kekoa Taparra, Scott C Lester, W Scott Harmsen, Molly Petersen, Ryan K Funk

Int J Part Ther· September 2020

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Altered Folate Homeostasis in Children with Down Syndrome: A Potential Basis for Enhanced Methotrexate Toxicity.
Ryan S Funk, Nasreen J Talib, Kanecia O Zimmerman, Leon van Haandel, Mara L Becker

J Pediatr· June 2020

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Mast Cell Degranulation Decreases Lipopolysaccharide-Induced Aortic Gene Expression and Systemic Levels of Interleukin-6 .
Jason M Springer, Vineesh V Raveendran, Mingcai Zhang, Ryan Funk, Donald D Smith

Mediators Inflamm· May 2020

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Immunogenicity in Clinical Practice and Drug Development: When is it Significant?
Valentina Shakhnovich, Bernd Meibohm, Amy Rosenberg, Andrzej M Kierzek, Rachel Hasenkamp, Ryan S Funk

Clin Transl Sci· March 2020

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Metabolomic Profiling to Identify Molecular Biomarkers of Cellular Response to Methotrexate In Vitro.
Ryan S Funk, Rakesh K Singh, Mara L Becker

Clin Transl Sci· January 2020

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Reducing seed migration to near zero with stranded-seed implants: Comparison of seed migration rates to the chest in 1000 permanent prostate brachytherapy patients undergoing implants with loose or stranded seeds.
Kenneth W Merrell, Brian J Davis, Christopher C Goulet, Keith M Furutani, Lance A Mynderse, Ryan K Funk

Brachytherapy· December 2019

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Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model.
Rakesh K Singh, Leon van Haandel, Paul Kiptoo, Mara L Becker, Teruna J Siahaan, Ryan S Funk

Eur J Pharmacol· June 2019

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Precision Pharmacotherapy: Integrating Pharmacogenomics into Clinical Pharmacy Practice.
J Kevin Hicks, Christina L Aquilante, Henry M Dunnenberger, Roseann S Gammal, Ryan S Funk

J Am Coll Clin Pharm· June 2019

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