Publications by authors named "Ryan Irvin"

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Impact of Genetic Risk Factors on Coronary Heart Disease Risk Across the Age Spectrum in Three Major Race/Ethnicity Groups in the United States.
Mohammadreza Naderian, Johanna L Smith, Marwan E Hamed, Ozan Dikilitas, Josh B Cortopassi, Ryan Irvin

medRxiv· November 2025

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Polygenic risk score for type 2 diabetes shows context-dependent effects across populations.
Boya Guo, Yanwei Cai, Daeeun Kim, Roelof A J Smit, Zhe Wang, Ryan M Irvin

Nat Commun· October 2025

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Whole genome sequence analysis of low-density lipoprotein cholesterol across 246 K individuals.
Margaret Sunitha Selvaraj, Xihao Li, Zilin Li, Eric Van Buren, Sara Haidermota, Ryan Irvin

Genome Biol· September 2025

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Histologic chorioamnionitis and fat mass accretion in infants born preterm.
Emily Gunawan, Viral G Jain, Shakia Hardy, M Ryan Irvin, Ariel A Salas

Pediatr Res· September 2025

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Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS.
Zsuzsanna Ament, Amit Patki, Varun M Bhave, Naruchorn Kijpaisalratana, Alana C Jones, M Ryan Irvin

Transl Stroke Res· June 2025

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White matter hyperintensity severity modifies gut metabolite association with cognitive outcomes.
Naruchorn Kijpaisalratana, Chia-Ling Phuah, Zsuzsanna Ament, Varun M Bhave, Ana-Lucia Garcia-Guarniz, M Ryan Irvin

J Prev Alzheimers Dis· April 2025

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Targeted Metabolomics in the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study.
Zsuzsanna Ament, Naruchorn Kijpaisalratana, Varun M Bhave, Catharine A Couch, Ana-Lucia Garcia Guarniz, M Ryan Irvin

Sci Data· March 2025

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Type 2 diabetes polygenic risk score demonstrates context-dependent effects and associations with type 2 diabetes-related risk factors and complications across diverse populations.
Boya Guo, Yanwei Cai, Daeeun Kim, Roelof A J Smit, Zhe Wang, Ryan M Irvin

medRxiv· February 2025

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Acetylglutamine Differentially Associated with First-Time Versus Recurrent Stroke.
Naruchorn Kijpaisalratana, Zsuzsanna Ament, Amit Patki, Varun M Bhave, Alana C Jones, M Ryan Irvin

Transl Stroke Res· October 2024

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Receipt of antimalarials among children aged 6-59 months in Nigeria from 2010 to 2021.
Sandra C Olisakwe, Julie Thwing, Jodie A Dionne, Ryan Irvin, Patrick S Kachur

Malar J· August 2024

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Plasma Metabolites and Life's Simple 7 in REGARDS.
Naruchorn Kijpaisalratana, Zsuzsanna Ament, Amit Patki, Varun M Bhave, Alana C Jones, M Ryan Irvin

Stroke· May 2024

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Sex-Associated Metabolites and Incident Stroke, Incident Coronary Heart Disease, Hypertension, and Chronic Kidney Disease in the REGARDS Cohort.
Catharine A Couch, Zsuzsanna Ament, Amit Patki, Naruchorn Kijpaisalratana, Varun Bhave, M Ryan Irvin

J Am Heart Assoc· May 2024

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Trimethylamine N-Oxide and White Matter Hyperintensity Volume Among Patients With Acute Ischemic Stroke.
Naruchorn Kijpaisalratana, Zsuzsanna Ament, Matthew B Bevers, Varun M Bhave, Ana-Lucia Garcia Guarniz, M Ryan Irvin

JAMA Netw Open· August 2023

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Gut microbiota-associated metabolites and risk of ischemic stroke in REGARDS.
Zsuzsanna Ament, Amit Patki, Varun M Bhave, Ninad S Chaudhary, Ana-Lucia Garcia Guarniz, M Ryan Irvin

J Cereb Blood Flow Metab· July 2023

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Hypertension severity, apparent treatment resistant hypertension and hyperuricemia in the REasons for Geographic And Racial Differences in Stroke (REGARDS) study.
Rikki M Tanner, Ninad Chaudary, Lisandro D Colantonio, Tony R Merriman, Richard J Reynolds, M Ryan Irvin

J Hypertens· June 2023

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Selection, optimization, and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse populations.
Niall J Lennon, Leah C Kottyan, Christopher Kachulis, Noura Abul-Husn, Josh Arias, Ryan Irvin

medRxiv· June 2023

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Association of Circulating Metabolites With Racial Disparities in Hypertension and Stroke in the REGARDS Study.
Naruchorn Kijpaisalratana, Zsuzsanna Ament, Amit Patki, Varun M Bhave, Ana-Lucia Garcia-Guarniz, M Ryan Irvin

Neurology· May 2023

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Plasma Metabolites Link Dietary Patterns to Stroke Risk.
Varun M Bhave, Zsuzsanna Ament, Amit Patki, Yan Gao, Naruchorn Kijpaisalratana, M Ryan Irvin

Ann Neurol· March 2023

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Nucleosides Associated With Incident Ischemic Stroke in the REGARDS and JHS Cohorts.
Zsuzsanna Ament, Amit Patki, Ninad Chaudhary, Varun M Bhave, Ana-Lucia Garcia Guarniz, M Ryan Irvin

Neurology· May 2022

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Genetic correlations between traits associated with hyperuricemia, gout, and comorbidities.
Richard J Reynolds, M Ryan Irvin, S Louis Bridges, Hwasoon Kim, Tony R Merriman

Eur J Hum Genet· September 2021

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PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.
Kellie A Mitchell, Justin Xavier Moore, Robert S Rosenson, Ryan Irvin, Faheem W Guirgis

PLoS One· November 2019

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Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.
Joshua C Bis, Colleen Sitlani, Ryan Irvin, Christy L Avery, Albert Vernon Smith

PLoS One· June 2016

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Lipid changes due to fenofibrate treatment are not associated with changes in DNA methylation patterns in the GOLDN study.
Mithun Das, M Ryan Irvin, Jin Sha, Stella Aslibekyan, Bertha Hidalgo

Front Genet· October 2015

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Epigenome-wide association study of fasting measures of glucose, insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network study.
Bertha Hidalgo, M Ryan Irvin, Jin Sha, Degui Zhi, Stella Aslibekyan

Diabetes· February 2014

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CPT1A: the future of heart disease detection and personalized medicine?
M Ryan Irvin, Stella Aslibekyan, Bertha Hidalgo, Donna Arnett

Clin Lipidol· January 2014

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