Publications by authors named "Ryan R Mitchell"

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Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.
Yannick D Benoit, Ryan R Mitchell, Wenliang Wang, Luca Orlando, Allison L Boyd

Cell Chem Biol· October 2021

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Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions.
Luca Orlando, Borko Tanasijevic, Mio Nakanishi, Jennifer C Reid, Juan L García-Rodríguez, Ryan R Mitchell

Cell Rep· March 2021

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Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients.
Lili Aslostovar, Allison L Boyd, Yannick D Benoit, Justin Di Lu, Juan Luis Garcia Rodriguez, Ryan R Mitchell

Cell Rep Med· February 2021

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Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells.
Mio Nakanishi, Ryan R Mitchell, Yannick D Benoit, Luca Orlando, Jennifer C Reid

Cell· May 2019

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Sam68 Allows Selective Targeting of Human Cancer Stem Cells.
Yannick D Benoit, Ryan R Mitchell, Ruth M Risueño, Luca Orlando, Borko Tanasijevic

Cell Chem Biol· July 2017

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Lineage-Specific Differentiation Is Influenced by State of Human Pluripotency.
Jong-Hee Lee, Sarah Laronde, Tony J Collins, Zoya Shapovalova, Borko Tanasijevic, Ryan R Mitchell

Cell Rep· April 2017

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Acquisition of pluripotency through continued environmental influence on OCT4-induced plastic human fibroblasts.
Kyle R Salci, Jung Bok Lee, Ryan R Mitchell, Luca Orlando, Aline Fiebig-Comyn

Stem Cell Res· July 2015

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Derivation of human induced pluripotent stem cells through continued exposure of OCT4-induced plastic human fibroblasts to reprogramming media.
Kyle R Salci, Jung Bok Lee, Ryan R Mitchell, Luca Orlando, Aline Fiebig-Comyn

Stem Cell Res· July 2015

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Single Transcription Factor Conversion of Human Blood Fate to NPCs with CNS and PNS Developmental Capacity.
Jong-Hee Lee, Ryan R Mitchell, Jamie D McNicol, Zoya Shapovalova, Sarah Laronde

Cell Rep· June 2015

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Somatic transcriptome priming gates lineage-specific differentiation potential of human-induced pluripotent stem cell states.
Jong-Hee Lee, Jung Bok Lee, Zoya Shapovalova, Aline Fiebig-Comyn, Ryan R Mitchell

Nat Commun· December 2014

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Activation of neural cell fate programs toward direct conversion of adult human fibroblasts into tri-potent neural progenitors using OCT-4.
Ryan R Mitchell, Eva Szabo, Yannick D Benoit, Daniel T Case, Rami Mechael

Stem Cells Dev· August 2014

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Structure of the endonuclease domain of MutL: unlicensed to cut.
Monica C Pillon, Jessica J Lorenowicz, Michael Uckelmann, Andrew D Klocko, Ryan R Mitchell

Mol Cell· July 2010

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