Publications by authors named "Ryan Sisk"

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Gene regulatory activity associated with polycystic ovary syndrome revealed DENND1A-dependent testosterone production.
Laavanya Sankaranarayanan, Kelly J Brewer, Shauna Morrow, Graham D Johnson, Alejandro Barrera, Ryan Sisk

Nat Commun· August 2025

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The Ontogeny of Distinct Reproductive Phenotypes in Girls at Risk for PCOS During the Postmenarchal Transition.
Laura C Torchen, Apoorva Aekka, Kelly Brewer, Ryan Sisk, Sarayu Ratnam

J Clin Endocrinol Metab· June 2025

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Clustering Identifies Subtypes With Different Phenotypic Characteristics in Women With Polycystic Ovary Syndrome.
Kim van der Ham, Loes M E Moolhuijsen, Kelly Brewer, Ryan Sisk, Andrea Dunaif

J Clin Endocrinol Metab· November 2024

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Single-cell profiling reveals inflammatory polarization of human carotid versus femoral plaque leukocytes.
Joshua Slysz, Arjun Sinha, Matthew DeBerge, Shalini Singh, Harris Avgousti, Ryan Sisk

JCI Insight· September 2023

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11-Oxygenated Androgen Metabolite Concentrations Are Affected by Pubertal Progression and Obesity.
Emily Breslow, Anya Taylor, Christine L Chan, Cameron Severn, Laura Pyle, Ryan Sisk

Horm Res Paediatr· August 2023

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Association between an AMH promoter polymorphism and serum AMH levels in PCOS patients.
Loes M E Moolhuijsen, Yvonne V Louwers, Anke McLuskey, Linda Broer, Andre G Uitterlinden, Ryan K Sisk

Hum Reprod· June 2022

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11-Oxygenated C19 Steroids Do Not Distinguish the Hyperandrogenic Phenotype of PCOS Daughters from Girls with Obesity.
Laura C Torchen, Ryan Sisk, Richard S Legro, Adina F Turcu, Richard J Auchus

J Clin Endocrinol Metab· November 2020

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Distinct subtypes of polycystic ovary syndrome with novel genetic associations: An unsupervised, phenotypic clustering analysis.
Matthew Dapas, Frederick T J Lin, Girish N Nadkarni, Ryan Sisk, Richard S Legro

PLoS Med· June 2020

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Publisher Correction: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.
M Geoffrey Hayes, Margrit Urbanek, David A Ehrmann, Loren L Armstrong, Ji Young Lee, Ryan Sisk

Nat Commun· April 2020

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Hyperandrogenemia is Common in Asymptomatic Women and is Associated with Increased Metabolic Risk.
Laura C Torchen, Joy N Tsai, Prathima Jasti, Rodrigo Macaya, Ryan Sisk

Obesity (Silver Spring)· January 2020

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Family-Based Quantitative Trait Meta-Analysis Implicates Rare Noncoding Variants in DENND1A in Polycystic Ovary Syndrome.
Matthew Dapas, Ryan Sisk, Richard S Legro, Margrit Urbanek, Andrea Dunaif

J Clin Endocrinol Metab· September 2019

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Pathogenic Anti-Müllerian Hormone Variants in Polycystic Ovary Syndrome.
Lidija K Gorsic, Gulum Kosova, Brian Werstein, Ryan Sisk, Richard S Legro

J Clin Endocrinol Metab· August 2017

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Increased antimüllerian hormone levels and other reproductive endocrine changes in adult male relatives of women with polycystic ovary syndrome.
Laura C Torchen, Ajay Kumar, Bhanu Kalra, Gopal Savjani, Ryan Sisk

Fertil Steril· July 2016

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Corrigendum: Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.
M Geoffrey Hayes, Margrit Urbanek, David A Ehrmann, Loren L Armstrong, Ji Young Lee, Ryan Sisk

Nat Commun· February 2016

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Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.
M Geoffrey Hayes, Margrit Urbanek, David A Ehrmann, Loren L Armstrong, Ji Young Lee, Ryan Sisk

Nat Commun· August 2015

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Parent-of-origin effects on glucose homeostasis in polycystic ovary syndrome.
Kristen Kobaly, Priyathama Vellanki, Ryan K Sisk, Loren Armstrong, Ji Young Lee

J Clin Endocrinol Metab· August 2014

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Mechanism for calcium ion sensing by the C2A domain of synaptotagmin I.
Jacob W Gauer, Ryan Sisk, Jesse R Murphy, Heathere Jacobson, R Bryan Sutton

Biophys J· July 2012

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