Publications by authors named "Ryan West"

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M102 activates both NRF2 and HSF1 transcription factor pathways and is neuroprotective in cell and animal models of amyotrophic lateral sclerosis.
Amy F Keerie, Raquel Rua Martins, Chloe F Allen, Katie Bowden, Sufana Al Mashhadi, Ryan J H West

Mol Neurodegener· November 2025

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Extreme exercise in males is linked to mTOR signalling and onset of amyotrophic lateral sclerosis.
David O'Brien, Elham Alhathli, Ceryl Harwood, Debarati Bhattacharya, Kriti Gupta, Ryan J H West

Brain· October 2025

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The balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells.
Róbert Zach, Michael Annis, Sandra M Martin-Guerrero, Abdulrahman Alatawi, Kim Hou Chia, Ryan West

Nat Commun· August 2025

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Molecular Basis for Asynchronous Chain Elongation During Rifamycin Antibiotic Biosynthesis.
Chengli Liu, Ryan C West, Muyuan Chen, Whitaker Cohn, George Wang

bioRxiv· July 2025

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Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras.
Charles W Parry, Francesca Pellicano, Alexander W Schüttelkopf, Kim S Beyer, Justin Bower, Christopher West, Ryan West

J Med Chem· May 2025

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A Novel DNA-Platinum Nanoparticle Conjugation Method for Attomolar Detection and Quantitation of Nucleic Acids Using the Microbubbling Digital Assay.
Ashvi S Jain, Ryan M West, Ravikiran Ramjee, Ping Wang

Anal Chem· April 2025

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RuvBL1/2 reduce toxic dipeptide repeat protein burden in multiple models of C9orf72-ALS/FTD.
Christopher P Webster, Bradley Hall, Olivia M Crossley, Dana Dauletalina, Marianne King, Ryan Jh West

Life Sci Alliance· February 2025

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Utilizing a Virtual Reality Matrix in Medical Education.
Dipal Mistry, Sarah Geevarughese, Callaham A Brock, Jacob Nelson, Danielle Drew, Ryan T West

Cureus· August 2024

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4-Phenyl-thiazole-based dual inhibitors of fatty acid amide hydrolase and soluble epoxide hydrolase do not alleviate orofacial inflammatory pain in female rats.
Daniel Carr, Christopher Chin, Tiffany Chacon, Monijeh Khoja Herawi, Michael Gonzalez, Ryan West

BBA Adv· August 2024

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Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.
Craig L Bennett, Somasish Dastidar, Frederick J Arnold, Spencer U McKinstry, Cameron Stockford, Ryan J H West

Acta Neuropathol Commun· October 2023

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Enhancing autophagy in Alzheimer's disease through drug repositioning.
Mehdi Eshraghi, Mazaher Ahmadi, Saeid Afshar, Shahrokh Lorzadeh, Aida Adlimoghaddam, Ryan West

Pharmacol Ther· September 2022

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Identification and Monitoring of Nucleotide Repeat Expansions Using Southern Blotting in Models of Motor Neuron Disease and Frontotemporal Dementia.
Joanne L Sharpe, Nikki S Harper, Ryan J H West

Bio Protoc· May 2022

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The tocopherol transfer protein mediates vitamin E trafficking between cerebellar astrocytes and neurons.
L Ulatowski, Mikel Ghelfi, Ryan West, J Atkinson, C J Finno

J Biol Chem· March 2022

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Modeling -Related Frontotemporal Dementia and Amyotrophic Lateral Sclerosis in .
Joanne L Sharpe, Nikki S Harper, Duncan R Garner, Ryan J H West

Front Cell Neurosci· October 2021

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Evaluation of a pharmacy technician-based medication prior authorization program.
Ron Carico, Ryan West, Tiffany Miller, Jessica Brown, Dustin Baum

J Am Pharm Assoc (2003)· August 2021

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Automated Generation of Novel Fragments Using Screening Data, a Dual SMILES Autoencoder, Transfer Learning and Syntax Correction.
Alan E Bilsland, Kirsten McAulay, Ryan West, Angelo Pugliese, Justin Bower

J Chem Inf Model· June 2021

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Lessons learned from CHMP2B, implications for frontotemporal dementia and amyotrophic lateral sclerosis.
Chris Ugbode, Ryan J H West

Neurobiol Dis· January 2021

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Neuroprotective activity of ursodeoxycholic acid in CHMP2B models of frontotemporal dementia.
Ryan J H West, Chris Ugbode, Laura Fort-Aznar, Sean T Sweeney

Neurobiol Dis· October 2020

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Co-expression of C9orf72 related dipeptide-repeats over 1000 repeat units reveals age- and combination-specific phenotypic profiles in Drosophila.
Ryan J H West, Joanne L Sharpe, André Voelzmann, Anna L Munro, Ines Hahn

Acta Neuropathol Commun· September 2020

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Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant CHMP2B toxicity in Drosophila.
Yubing Lu, Ryan J H West, Marine Pons, Sean T Sweeney, Fen-Biao Gao

Sci Rep· August 2020

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Regression modelling of the impact of confectioner's sugar and temperature on palm oil crystallization and rheology.
Ryan West, Dérick Rousseau

Food Chem· February 2019

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Reactive oxygen species regulate activity-dependent neuronal plasticity in .
Matthew Cw Oswald, Paul S Brooks, Maarten F Zwart, Amrita Mukherjee, Ryan Jh West

Elife· December 2018

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Autism sensory dysfunction in an evolutionarily conserved system.
Greta Vilidaite, Anthony M Norcia, Ryan J H West, Christopher J H Elliott, Francesca Pei

Proc Biol Sci· December 2018

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Sphingolipids regulate neuromuscular synapse structure and function in Drosophila.
Ryan J H West, Laura Briggs, Maria Perona Fjeldstad, Richard R Ribchester, Sean T Sweeney

J Comp Neurol· September 2018

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Metal-free selective mono-halodecarboxylation of heteroarenes under mild conditions.
Scott H Henderson, Ryan A West, Simon E Ward, Mark A Honey

R Soc Open Sci· June 2018

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