Publications by authors named "Ryo Goitsuka"

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Drug Repurposing Screen Identifies Pimozide as a ROS-Inducing Therapy With Anti-Tumor Efficacy in HNSCC PDX Models.
Shogo Okazaki, Shintaro Nakamura, Tomoya Soma, Momoko Yoshikawa, Seiji Asoda, Ryo Goitsuka

Cancer Sci· November 2025

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Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions.
Yuka Nozaki, Masaki Kobayashi, Tomoyoshi Fukuoh, Mamiko Ishimatsu, Takumi Narita, Ryo Goitsuka

Sci Rep· April 2025

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B Cells of Early-life Origin Defined by RAG2-based Lymphoid Cell Tracking under Native Hematopoietic Conditions.
Keiko Fujisaki, Shogo Okazaki, Shuhei Ogawa, Miyama Takeda, Eiji Sugihara, Ryo Goitsuka

J Immunol· August 2024

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The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor.
Atsuya Sawabe, Shogo Okazaki, Akira Nakamura, Ryo Goitsuka, Tomonori Kaifu

J Leukoc Biol· April 2024

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The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor.
Akihisa Oda, Shoko Furukawa, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Ryo Goitsuka

Thromb Res· November 2023

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Lack of Herpes Virus Entry Mediator Signals in Thymocytes Impairs Conventional CD8 T Cell Selection and Promotes Memory-like CD8 T Cell Development.
Yuki Kugii, Yui Kuroki, Yasushi Hara, Ryo Goitsuka, Naoko Nakano

J Immunol· May 2023

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Loss of CAPS2/Cadps2 leads to exocrine pancreatic cell injury and intracellular accumulation of secretory granules in mice.
Yotaroh Sato, Miho Tsuyusaki, Hiromi Takahashi-Iwanaga, Rena Fujisawa, Atsushi Masamune, Ryo Goitsuka

Front Mol Biosci· November 2022

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MOZ is critical for the development of MOZ/MLL fusion-induced leukemia through regulation of Hoxa9/Meis1 expression.
Takuo Katsumoto, Yoko Ogawara, Kazutsune Yamagata, Yukiko Aikawa, Ryo Goitsuka

Blood Adv· October 2022

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C/EBPβ induces B-cell acute lymphoblastic leukemia and cooperates with BLNK mutations.
Morito Kurata, Iichiro Onishi, Tomoko Takahara, Yukari Yamazaki, Sachiko Ishibashi, Ryo Goitsuka

Cancer Sci· December 2021

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TC10, a Rho family GTPase, is required for efficient axon regeneration in a neuron-autonomous manner.
Shingo Koinuma, Ryota Negishi, Riko Nomura, Kazuki Sato, Takuya Kojima, Ryo Goitsuka

J Neurochem· May 2021

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Transcription factor Tlx1 marks a subset of lymphoid tissue organizer-like mesenchymal progenitor cells in the neonatal spleen.
Yuta Ueno, Keiko Fujisaki, Shoko Hosoda, Yusuke Amemiya, Shogo Okazaki, Ryo Goitsuka

Sci Rep· December 2019

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Nuclear localization of Meis1 in dermal papilla promotes hair matrix cell proliferation in the anagen phase of hair cycle.
Masato Namekata, Masakuni Yamamoto, Ryo Goitsuka

Biochem Biophys Res Commun· November 2019

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High-affinity IgM memory B cells are defective in differentiation into IgM antibody-secreting cells by re-stimulation with a T cell-dependent antigen.
Yasuyuki Tashiro, Akikazu Murakami, Yasushi Hara, Takeyuki Shimizu, Masato Kubo, Ryo Goitsuka

Sci Rep· September 2018

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Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1.
Akihisa Oda, Toshiki Tezuka, Yuta Ueno, Shoko Hosoda, Yusuke Amemiya, Ryo Goitsuka

Sci Rep· May 2018

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Germ cell-intrinsic requirement for the homeodomain transcription factor PKnox1/Prep1 in adult spermatogenesis.
Yasuhiro Kawai, Akihisa Oda, Yoshiakira Kanai, Ryo Goitsuka

PLoS One· February 2018

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Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.
Tomoo Owa, Shinichiro Taya, Satoshi Miyashita, Mariko Yamashita, Toma Adachi, Ryo Goitsuka

J Neurosci· January 2018

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Loss of the Homeodomain Transcription Factor Prep1 Perturbs Adult Hematopoiesis in the Bone Marrow.
Kentaro Yoshioka, Akihisa Oda, Chihiro Notsu, Takafumi Ohtsuka, Yasuhiro Kawai, Ryo Goitsuka

PLoS One· May 2016

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MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis.
Takashi Yokoyama, Mayuka Nakatake, Takeshi Kuwata, Arnaud Couzinet, Ryo Goitsuka

J Clin Invest· May 2016

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Meis1 regulates epidermal stem cells and is required for skin tumorigenesis.
Kazuhiro Okumura, Megumi Saito, Eriko Isogai, Yoshimasa Aoto, Tsuyoshi Hachiya, Ryo Goitsuka

PLoS One· March 2015

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Meis1 is required for the maintenance of postnatal thymic epithelial cells.
Takehiro Hirayama, Yusuke Asano, Hajime Iida, Takeshi Watanabe, Takuro Nakamura, Ryo Goitsuka

PLoS One· February 2015

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Promotion of crystalline cellulose degradation by expansins from Oryza sativa.
Yasutaka Seki, Yukiko Kikuchi, Ryo Yoshimoto, Kenichi Aburai, Yoshihiro Kanai, Ryo Goitsuka

Planta· January 2015

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Homeodomain transcription factor Meis1 is a critical regulator of adult bone marrow hematopoiesis.
Reina Ariki, Satoru Morikawa, Yo Mabuchi, Sadafumi Suzuki, Mayuka Nakatake, Ryo Goitsuka

PLoS One· December 2014

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Generation of a Tlx1(CreER-Venus) knock-in mouse strain for the study of spleen development.
Ryo Nakahara, Yasuhiro Kawai, Akihisa Oda, Miyuki Nishimura, Akikazu Murakami, Ryo Goitsuka

Genesis· November 2014

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SLP-76 is required for high-affinity IgE receptor- and IL-3 receptor-mediated activation of basophils.
Shinya Hidano, Daisuke Kitamura, Lalit Kumar, Raif S Geha, Ryo Goitsuka

Int Immunol· November 2012

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Blocking S1P interaction with S1P₁ receptor by a novel competitive S1P₁-selective antagonist inhibits angiogenesis.
Yasuyuki Fujii, Yasuji Ueda, Hidenori Ohtake, Naoya Ono, Tetsuo Takayama, Ryo Goitsuka

Biochem Biophys Res Commun· March 2012

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