Publications by authors named "Ryuji Inoue"

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Dynamic remodeling of TRPC5 channel-caveolin-1-eNOS protein assembly potentiates the positive feedback interaction between Ca and NO signals.
Reiko Sakaguchi, Nobuaki Takahashi, Takashi Yoshida, Nozomi Ogawa, Yoshifumi Ueda, Ryuji Inoue

J Biol Chem· September 2024

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The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis.
Yaopeng Hu, Jiehui Cang, Keizo Hiraishi, Takayuki Fujita, Ryuji Inoue

Int J Mol Sci· July 2023

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Potential of the TRPM7 channel as a novel therapeutic target for pulmonary arterial hypertension.
Keizo Hiraishi, Lin Hai Kurahara, Kaori Ishikawa, Tetsuhiko Go, Naoya Yokota, Ryuji Inoue

J Smooth Muscle Res· August 2022

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Critical contributions of pre-S1 shoulder and distal TRP box in DAG-activated TRPC6 channel by PIP regulation.
Masayuki X Mori, Ryo Okada, Reiko Sakaguchi, Hideharu Hase, Yuko Imai, Ryuji Inoue

Sci Rep· June 2022

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Theoretical Investigation of the Mechanism by which A Gain-of-Function Mutation of the TRPM4 Channel Causes Conduction Block.
Yaopeng Hu, Qin Li, Yanghua Shen, Takayuki Fujita, Xin Zhu, Ryuji Inoue

Int J Mol Sci· August 2021

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Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension.
Keizo Hiraishi, Lin Hai Kurahara, Jianlin Feng, Aya Yamamura, Yuanyuan Cui, Ryuji Inoue

Transl Res· July 2021

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An Arrhythmic Mutation E7K Facilitates TRPM4 Channel Activation via Enhanced PIP Interaction.
Yaopeng Hu, Qin Li, Lin-Hai Kurahara, Narumi Shioi, Keizo Hiraishi, Ryuji Inoue

Cells· April 2021

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Pathological activation of CaMKII induces arrhythmogenicity through TRPM4 overactivation.
Yaopeng Hu, Daniela Ross Kaschitza, Maria Essers, Prakash Arullampalam, Takayuki Fujita, Ryuji Inoue

Pflugers Arch· March 2021

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Volume-regulated chloride channel regulates cell proliferation and is involved in the possible interaction between TMEM16A and LRRC8A in human metastatic oral squamous cell carcinoma cells.
Shohei Yoshimoto, Miho Matsuda, Kenichi Kato, Eijiro Jimi, Hiroshi Takeuchi, Ryuji Inoue

Eur J Pharmacol· March 2021

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Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn.
Lin Hai Kurahara, Keizo Hiraishi, Aya Yamamura, Ying Zhang, Kohtaro Abe, Ryuji Inoue

J Mol Cell Cardiol· November 2020

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Implications of immune-inflammatory responses in smooth muscle dysfunction and disease.
Fumitake Usui-Kawanishi, Masafumi Takahashi, Hiroyasu Sakai, Wataru Suto, Yuki Kai, Ryuji Inoue

J Smooth Muscle Res· July 2020

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SGLT2 inhibitor ipragliflozin attenuates breast cancer cell proliferation.
Shiho Komatsu, Takashi Nomiyama, Tomohiro Numata, Takako Kawanami, Yuriko Hamaguchi, Ryuji Inoue

Endocr J· January 2020

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TRP channels in cardiac and intestinal fibrosis.
Ryuji Inoue, Lin-Hai Kurahara, Keizo Hiraishi

Semin Cell Dev Biol· October 2019

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Endoscopic Biliary Intervention Using Traction Devices for Periampullary Diverticulum.
Ryuji Inoue, Hiroshi Kawakami, Yoshimasa Kubota, Tessin Ban

Intern Med· October 2019

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Contribution of Coiled-Coil Assembly to Ca/Calmodulin-Dependent Inactivation of TRPC6 Channel and its Impacts on FSGS-Associated Phenotypes.
Onur K Polat, Masatoshi Uno, Terukazu Maruyama, Ha Nam Tran, Kayo Imamura, Ryuji Inoue

J Am Soc Nephrol· September 2019

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Construction of a Fluorescent Screening System of Allosteric Modulators for the GABA Receptor Using a Turn-On Probe.
Seiji Sakamoto, Kei Yamaura, Tomohiro Numata, Fumio Harada, Kazuma Amaike, Ryuji Inoue

ACS Cent Sci· September 2019

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Integrative and theoretical research on the architecture of a biological system and its disorder.
Shinichi Uchida, Yoshiyuki Asai, Yoshiaki Kariya, Kunichika Tsumoto, Hiroshi Hibino, Ryuji Inoue

J Physiol Sci· May 2019

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Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel.
Keizo Hiraishi, Lin-Hai Kurahara, Miho Sumiyoshi, Yao-Peng Hu, Kaori Koga, Ryuji Inoue

World J Gastroenterol· September 2018

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TRPM7-mediated spontaneous Ca entry regulates the proliferation and differentiation of human leukemia cell line K562.
Kiriko Takahashi, Chisato Umebayashi, Tomohiro Numata, Akira Honda, Jun Ichikawa, Ryuji Inoue

Physiol Rep· July 2018

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Cellular mechanism for herbal medicine Junchoto to facilitate intestinal Cl/water secretion that involves cAMP-dependent activation of CFTR.
Tomohiro Numata, Kaori Sato-Numata, Yasunobu Okada, Ryuji Inoue

J Nat Med· June 2018

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Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease.
Lin Hai Kurahara, Keizo Hiraishi, Yaopeng Hu, Kaori Koga, Miki Onitsuka, Ryuji Inoue

Cell Mol Gastroenterol Hepatol· March 2018

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Mechano-sensitivity of mitochondrial function in mouse cardiac myocytes.
Gentaro Iribe, Keiko Kaihara, Yohei Yamaguchi, Michio Nakaya, Ryuji Inoue

Prog Biophys Mol Biol· November 2017

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Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing.
Tomohiro Numata, Kunichika Tsumoto, Kazunori Yamada, Tatsuki Kurokawa, Shinichi Hirose, Ryuji Inoue

Sci Rep· August 2017

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Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches.
Yaopeng Hu, Yubin Duan, Ayako Takeuchi, Lin Hai-Kurahara, Jun Ichikawa, Ryuji Inoue

Cardiovasc Res· August 2017

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Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction.
Michio Nakaya, Kenji Watari, Mitsuru Tajima, Takeo Nakaya, Shoichi Matsuda, Ryuji Inoue, Kazuhide Inoue

J Clin Invest· January 2017

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