Publications by authors named "S Capacchi"

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Discovery of CHF-6523, an Inhaled Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease.
Paolo Bruno, Daniele Pala, Alessandra Micoli, Mauro Corsi, Alessandro Accetta, Silvia Capacchi

J Med Chem· February 2025

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Discovery and Optimization of Pyridazinones as PI3Kδ Selective Inhibitors for Administration by Inhalation.
Paolo Bruno, Alessandra Micoli, Mauro Corsi, Daniele Pala, Sara Guariento, Silvia Capacchi

J Med Chem· July 2024

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Discovery and Optimization of Thiazolidinyl and Pyrrolidinyl Derivatives as Inhaled PDE4 Inhibitors for Respiratory Diseases.
Laura Carzaniga, Gabriele Amari, Andrea Rizzi, Carmelida Capaldi, Renato De Fanti, Silvia Capacchi

J Med Chem· December 2017

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Atropisomerism and Conformational Equilibria: Impact on PI3Kδ Inhibition of 2-((6-Amino-9H-purin-9-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one (IC87114) and Its Conformationally Restricted Analogs.
Alessio Lodola, Serena Bertolini, Matteo Biagetti, Silvia Capacchi, Fabrizio Facchinetti

J Med Chem· May 2017

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Novel class of benzoic acid ester derivatives as potent PDE4 inhibitors for inhaled administration in the treatment of respiratory diseases.
Elisabetta Armani, Gabriele Amari, Andrea Rizzi, Renato De Fanti, Eleonora Ghidini, Silvia Capacchi

J Med Chem· February 2014

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