Publications by authors named "S M Sebti"

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Geranylgeranyl transferase-1 inhibitor GGTI-2417 enhances the anti-tumour efficacy of histone deacetylase inhibitors in different T-cell lymphoma lines.
Xiaoyan Hu, Lin Li, Jewel Nkwocha, Hitesh Vasiyani, Aslamuzzaman Kazi, Said Sebti

Br J Haematol· December 2025

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IL-33-mediated mast cell and eosinophil function requires isoprenylation.
Jason R Burchett, Aditya Kotha, Destiny T Davis, Kaitlyn G Jackson, Jordan M Dailey, Said M Sebti

Front Immunol· December 2025

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Pitavastatin counteracts venetoclax resistance mechanisms in acute myeloid leukemia by depleting geranylgeranyl pyrophosphate.
Roberta Buono, Dennis Juarez, Madhuri Paul, Sarah J Skuli, Ian B Wong, Said M Sebti

bioRxiv· November 2025

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Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response.
Sarah J Skuli, A'ishah Bakayoko, Marisa Kruidenier, Bryan Manning, Paige Pammer, Said M Sebti

Leukemia· September 2025

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Design and Evaluation of Bivalent K-Ras Inhibitors That Target the CAAX Binding Site and the Acidic Surface of Farnesyltransferase and Geranylgeranyltransferase I.
Naomi Horiuchi, Rania Omer, Fumitoshi Sugino, Nanami Ogino, Yoshihisa Inoue, Said M Sebti

Chemistry· May 2025

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