Publications by authors named "Sabine Spath"

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FcRn-silencing of IL-12Fc prevents toxicity of local IL-12 therapy and prolongs survival in experimental glioblastoma.
Michal Beffinger, Linda Schellhammer, Betül Taskoparan, Sereina Deplazes, Ulisse Salazar, Sabine Spath

Nat Commun· May 2025

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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Lynn Bonetti, Veronika Horkova, Melanie Grusdat, Joseph Longworth, Luana Guerra, Sabine Spath

Cell Metab· August 2024

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SKI Regulates Medullary Thymic Epithelial Cell Differentiation to Control Peripheral T Cell Responses in Mice.
Honyin Chiu, Kristin N Weinstein, Sabine Spath, Alex Hu, Stephanie Varela

J Immunol· July 2024

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A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation.
Lynn Bonetti, Veronika Horkova, Joseph Longworth, Luana Guerra, Henry Kurniawan, Sabine Spath

bioRxiv· July 2023

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Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes.
Sabine Spath, Florence Roan, Scott R Presnell, Barbara Höllbacher, Steven F Ziegler

iScience· September 2022

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FOXP3 exon 2 controls T stability and autoimmunity.
Jianguang Du, Qun Wang, Shuangshuang Yang, Si Chen, Yongyao Fu, Sabine Spath

Sci Immunol· June 2022

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Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β.
Juliana Komuczki, Selma Tuzlak, Ekaterina Friebel, Tom Hartwig, Sabine Spath

Immunity· May 2019

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Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.
Sonia Tugues, Ana Amorim, Sabine Spath, Guillaume Martin-Blondel, Bettina Schreiner

Sci Transl Med· November 2018

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Erratum: Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.
Nimitha R Mathew, Francis Baumgartner, Lukas Braun, David O'Sullivan, Simone Thomas, Sabine Spath

Nat Med· April 2018

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Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.
Nimitha R Mathew, Francis Baumgartner, Lukas Braun, David O'Sullivan, Simone Thomas, Sabine Spath

Nat Med· March 2018

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Dysregulation of the Cytokine GM-CSF Induces Spontaneous Phagocyte Invasion and Immunopathology in the Central Nervous System.
Sabine Spath, Juliana Komuczki, Mario Hermann, Pawel Pelczar, Florian Mair

Immunity· February 2017

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Cytokine networks in neuroinflammation.
Burkhard Becher, Sabine Spath, Joan Goverman

Nat Rev Immunol· January 2017

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GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage.
Andrew L Croxford, Sabine Spath, Burkhard Becher

Trends Immunol· October 2015

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Helicobacter pylori-specific protection against inflammatory bowel disease requires the NLRP3 inflammasome and IL-18.
Daniela B Engler, Irina Leonardi, Mara L Hartung, Andreas Kyburz, Sabine Spath

Inflamm Bowel Dis· April 2015

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T-bet or not T-bet: taking the last bow on the autoimmunity stage.
Sabine Spath, Burkhard Becher

Eur J Immunol· November 2013

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