Publications by authors named "Sabrina Adam"

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One Month of Brief Weekly Magnetic Field Therapy Enhances the Anticancer Potential of Female Human Sera: Randomized Double-Blind Pilot Study.
Jan Nikolas Iversen, Yee Kit Tai, Jasmine Lye Yee Yap, Rafhanah Banu Binte Abdul Razar, Viresh Krishnan Sukumar, Sabrina Adam

Cells· February 2025

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On the accuracy of the epigenetic copy machine: comprehensive specificity analysis of the DNMT1 DNA methyltransferase.
Sabrina Adam, Viviane Klingel, Nicole E Radde, Pavel Bashtrykov, Albert Jeltsch

Nucleic Acids Res· July 2023

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The R736H cancer mutation in DNMT3A modulates the properties of the FF-subunit interface.
Stefan Kunert, Max Emperle, Sabrina Adam, Julia Bräcker, Jens Brockmeyer

Biochimie· May 2023

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Genome-wide deposition of 6-methyladenine in human DNA reduces the viability of HEK293 cells and directly influences gene expression.
Julian Broche, Anja R Köhler, Fiona Kühnel, Bernd Osteresch, Thyagarajan T Chandrasekaran, Sabrina Adam

Commun Biol· February 2023

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DNA methyltransferase DNMT3A forms interaction networks with the CpG site and flanking sequence elements for efficient methylation.
Michael Dukatz, Marianna Dittrich, Elias Stahl, Sabrina Adam, Alex de Mendoza

J Biol Chem· October 2022

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Preferential Self-interaction of DNA Methyltransferase DNMT3A Subunits Containing the R882H Cancer Mutation Leads to Dominant Changes of Flanking Sequence Preferences.
Alexandra Mack, Max Emperle, Philipp Schnee, Sabrina Adam, Jürgen Pleiss

J Mol Biol· April 2022

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Methylation of recombinant mononucleosomes by DNMT3A demonstrates efficient linker DNA methylation and a role of H3K36me3.
Alexander Bröhm, Tabea Schoch, Michael Dukatz, Nora Graf, Franziska Dorscht, Sabrina Adam

Commun Biol· March 2022

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Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns.
Sabrina Adam, Julia Bräcker, Viviane Klingel, Bernd Osteresch, Nicole E Radde

Commun Biol· January 2022

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Deep Enzymology Studies on DNA Methyltransferases Reveal Novel Connections between Flanking Sequences and Enzyme Activity.
Albert Jeltsch, Sabrina Adam, Michael Dukatz, Max Emperle, Pavel Bashtrykov

J Mol Biol· September 2021

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Structural and biochemical insight into the mechanism of dual CpG site binding and methylation by the DNMT3A DNA methyltransferase.
Max Emperle, Disha M Bangalore, Sabrina Adam, Stefan Kunert, Hannah S Heil

Nucleic Acids Res· August 2021

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Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase.
Michael Dukatz, Sabrina Adam, Mahamaya Biswal, Jikui Song, Pavel Bashtrykov

Nucleic Acids Res· November 2020

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Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Linfeng Gao, Max Emperle, Yiran Guo, Sara A Grimm, Wendan Ren, Sabrina Adam

Nat Commun· July 2020

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DNA sequence-dependent activity and base flipping mechanisms of DNMT1 regulate genome-wide DNA methylation.
Sabrina Adam, Hiwot Anteneh, Maximilian Hornisch, Vincent Wagner, Jiuwei Lu

Nat Commun· July 2020

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Engineering of Effector Domains for Targeted DNA Methylation with Reduced Off-Target Effects.
Daniel Hofacker, Julian Broche, Laura Laistner, Sabrina Adam, Pavel Bashtrykov

Int J Mol Sci· January 2020

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Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns.
Max Emperle, Sabrina Adam, Stefan Kunert, Michael Dukatz, Annika Baude

Nucleic Acids Res· December 2019

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