Publications by authors named "Safa Larafa"

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Autophagy suppression via SRC induction represents a therapeutic vulnerability for -mutant cancers.
Silvia Vega-Rubin-de-Celis, Amanda Kristani, Matthias Kudla, Svenja Mergener, Andrés Corrochano-Ruiz, Safa Larafa

Autophagy· December 2025

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Targeting hypoxia-inducible factor-1 in a hypoxidative stress model protects retinal pigment epithelium cells from cell death and metabolic dysregulation.
Annika Schubert, Maria Eduarda Lobo Barbosa da Silva, Tabea Ambrock, Orbel Terosian, Anna Malyshkina, Safa Larafa

Cell Death Discov· August 2025

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α-Ketoglutarate supplementation and NAD+ modulation enhance metabolic rewiring and radiosensitization in SLC25A1 inhibited cancer cells.
Kexu Xiang, Mikhail Kunin, Safa Larafa, Maike Busch, Nicole Dünker

Cell Death Discov· January 2024

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Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1α under normoxia.
Yoshiyuki Henning, Katrin Willbrand, Safa Larafa, Gesa Weißenberg, Veronika Matschke

Cell Death Discov· October 2023

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Targeting AKT-Dependent Regulation of Antioxidant Defense Sensitizes AKT-E17K Expressing Cancer Cells to Ionizing Radiation.
Isabell Goetting, Safa Larafa, Katharina Eul, Mikhail Kunin, Burkhard Jakob

Front Oncol· July 2022

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Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.
Yoshiyuki Henning, Ursula Sarah Blind, Safa Larafa, Johann Matschke, Joachim Fandrey

Cell Death Dis· July 2022

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Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown.
Adam Krysztofiak, Klaudia Szymonowicz, Julian Hlouschek, Kexu Xiang, Christoph Waterkamp, Safa Larafa

iScience· November 2021

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Metabolic reprograming of antioxidant defense: a precision medicine perspective for radiotherapy of lung cancer?
Johann Matschke, Safa Larafa, Verena Jendrossek

Biochem Soc Trans· June 2021

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