Publications by authors named "Said Akli"

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Endocannabinoid signaling is a critical link between circadian desynchronization and metabolic dysfunction.
Brennan A Baca, Giancarlo E Denaroso, Said Akli, Gregory L Pearson, Jiexin Wang

bioRxiv· October 2025

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An Automated Analysis Pipeline for Microglia Morphology in Nikon NIS-Elements.
Grace Garman, Stephanie Gottwals, Gregory Pearson, Saïd Akli, Hanna Hlukhova

J Biomol Tech· July 2025

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Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis.
Amriti R Lulla, Said Akli, Cansu Karakas, Joseph A Caruso, Lucas D Warma

Mol Cancer Ther· April 2024

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LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers.
Amriti R Lulla, Said Akli, Cansu Karakas, Min Jin Ha, Natalie W Fowlkes

Oncogenesis· May 2021

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Cytoplasmic Cyclin E and Phospho-Cyclin-Dependent Kinase 2 Are Biomarkers of Aggressive Breast Cancer.
Cansu Karakas, Anna Biernacka, Tuyen Bui, Aysegul A Sahin, Min Yi, Said Akli

Am J Pathol· July 2016

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Hbo1 is a cyclin E/CDK2 substrate that enriches breast cancer stem-like cells.
Mylinh T Duong, Said Akli, Sira Macalou, Anna Biernacka, Bisrat G Debeb

Cancer Res· September 2013

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LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients.
MyLinh T Duong, Said Akli, Caimiao Wei, Hannah F Wingate, Wenbin Liu

PLoS Genet· September 2012

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Low molecular weight cyclin E is associated with p27-resistant, high-grade, high-stage and invasive bladder cancer.
Said Akli, Xin-Qiao Zhang, Jolanta Bondaruk, Susan L Tucker, P Bogdan Czerniak

Cell Cycle· April 2012

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Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of cyclin E.
Said Akli, Carolyn S Van Pelt, Tuyen Bui, Laurent Meijer, Khandan Keyomarsi

Cancer Res· May 2011

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Low-molecular-weight cyclin E can bypass letrozole-induced G1 arrest in human breast cancer cells and tumors.
Said Akli, Tuyen Bui, Hannah Wingate, Anna Biernacka, Stacy Moulder

Clin Cancer Res· February 2010

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Overexpression of the low molecular weight cyclin E in transgenic mice induces metastatic mammary carcinomas through the disruption of the ARF-p53 pathway.
Said Akli, Carolyn S Van Pelt, Tuyen Bui, Asha S Multani, Sandy Chang

Cancer Res· August 2007

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Deregulation of cyclin E meets dysfunction in p53: closing the escape hatch on breast cancer.
Michelle Craig Barton, Said Akli, Khandan Keyomarsi

J Cell Physiol· December 2006

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Low-molecular-weight cyclin E: the missing link between biology and clinical outcome.
Said Akli, Khandan Keyomarsi

Breast Cancer Res· October 2004

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The low molecular weight (LMW) isoforms of cyclin E deregulate the cell cycle of mammary epithelial cells.
Hannah Wingate, Isabelle Bedrosian, Said Akli, Khandan Keyomarsi

Cell Cycle· May 2004

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Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer.
Said Akli, Ping-Ju Zheng, Asha S Multani, Hannah F Wingate, Sen Pathak

Cancer Res· May 2004

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Cyclin E and its low molecular weight forms in human cancer and as targets for cancer therapy.
Said Akli, Khandan Keyomarsi

Cancer Biol Ther· February 2004

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