Publications by authors named "Saiful E Syafruddin"

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A Comparative Analysis of , , and Expression in Cumulus Cells Among Women with Diminished Ovarian Reserve Following Rescue In Vitro Maturation (r-IVM).
Mohd Faizal Ahmad, Marjanu Hikmah Elias, Norazilah Mat Jin, Muhammad Azrai Abu, Saiful Effendi Syafruddin

Life (Basel)· October 2025

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CRISPR/Cas9 mediated ENT2 gene knockout altered purine catabolic pathway and induced apoptosis in colorectal cell lines.
Safaa M Naes, Sharaniza Ab-Rahim, Musalmah Mazlan, Saiful Effendi Syafruddin, M Aiman Mohtar

PLoS One· September 2025

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RNA sequencing-based profiling of differentially expressed microRNAs in endothelial cells from offspring of hypertensive pregnancies: a preliminary study.
Nurul Iffah Mohd Isa, Aslah Nabilah Abdull Sukor, Saiful Effendi Syafruddin, Mohd Faizal Ahmad, Shahidee Zainal Abidin

Front Mol Biosci· September 2025

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Comparative Analysis of Rescue-In Vitro-Maturation (r-IVM) Outcomes in Women with Diminished Ovarian Reserve (DOR) Versus Normal Ovarian Reserve (NOR).
Mohd Faizal Ahmad, Nurul Yaqin Mohd Nor, Mohammad Mahmoud Mohammad Ramadneh, Nurul Izyani Roseli, Marjanu Hikmah Elias, Saiful Effendi Syafruddin

Biomedicines· April 2025

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Introduction of a single-nucleotide variant, rs16851030, into the gene increased cellular susceptibility to hypoxia.
Poh Kuan Wong, Saiful Effendi Syafruddin, Fook Choe Cheah, Norazrina Azmi, Pei Yuen Ng

Per Med· December 2024

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Oocytes Quality Assessment-The Current Insight: A Systematic Review.
Mohd Faizal Ahmad, Marjanu Hikmah Elias, Norazilah Mat Jin, Muhammad Azrai Abu, Saiful Effendi Syafruddin

Biology (Basel)· November 2024

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IL-8 and PI3K pathway influence the susceptibility of TRAIL-sensitive colorectal cancer cells to TRAIL-induced cell death.
Kelly Xue Jing Jong, Elsa Haniffah Mejia Mohamed, Saiful Effendi Syafruddin, Farid Nazer Faruqu, Kumutha Malar Vellasamy

Mol Biol Rep· September 2024

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Cholesterol accumulation in ccRCC: the role of ccRCC-initiating VHL-HIFα pathway.
M Aiman Mohtar, Siti Nur Hasanah Mohd Yusuf, Saiful Effendi Syafruddin

EBioMedicine· May 2024

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dCas9 Tells Tales: Probing Gene Function and Transcription Regulation in Cancer.
Nurul Nadia Mohamad Zamberi, Asmaa Y Abuhamad, Teck Yew Low, M Aiman Mohtar, Saiful Effendi Syafruddin

CRISPR J· April 2024

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Unravelling the role of HAS2, GREM1, and PTGS2 gene expression in cumulus cells: implications for human oocyte development competency - a systematic review and integrated bioinformatic analysis.
Ahmad Mohd Faizal, Marjanu Hikmah Elias, Norazilah Mat Jin, Muhammad Azrai Abu, Saiful Effendi Syafruddin

Front Endocrinol (Lausanne)· March 2024

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Insights into the molecular mechanisms and signalling pathways of epithelial to mesenchymal transition (EMT) in colorectal cancer: A systematic review and bioinformatic analysis of gene expression.
Suha Azizan, Kim Jun Cheng, Elsa Haniffah Mejia Mohamed, Kamariah Ibrahim, Farid Nazer Faruqu, Saiful Effendi Syafruddin

Gene· February 2024

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Potential Roles of microRNAs for Assessing Cardiovascular Risk in Pre-Eclampsia-Exposed Postpartum Women and Offspring.
Nurul Iffah Mohd Isa, Saiful Effendi Syafruddin, Mohd Helmy Mokhtar, Shahidee Zainal Abidin, Farah Hanan Fathihah Jaffar

Int J Mol Sci· November 2023

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Expression of Gene in Women with Endometriosis: A Systematic Review.
Nurunnajah Lazim, Marjanu Hikmah Elias, Zulazmi Sutaji, Abdul Kadir Abdul Karim, Mohammad Azrai Abu, Saiful Effendi Syafruddin

Int J Mol Sci· August 2023

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The spectrum of maturation in clinical practice: the current insight.
Mohd Faizal Ahmad, Marjanu Hikmah Elias, Norazilah Mat Jin, Muhammad Azrai Abu, Saiful Effendi Syafruddin

Front Endocrinol (Lausanne)· July 2023

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The Promises and Pitfalls of CRISPR-Mediated Base Editing in Stem Cells.
Poh Kuan Wong, Nurul Nadia Mohamad Zamberi, Saiful Effendi Syafruddin, Fook Choe Cheah, Norazrina Azmi

CRISPR J· June 2023

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Impact of the Cancer Cell Secretome in Driving Breast Cancer Progression.
Syazalina Zahari, Saiful Effendi Syafruddin, M Aiman Mohtar

Cancers (Basel)· May 2023

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Profiling of Differentially Expressed MicroRNAs in Human Umbilical Vein Endothelial Cells Exposed to Hyperglycemia via RNA Sequencing.
Nur Syakirah Othman, Amilia Aminuddin, Shahidee Zainal Abidin, Saiful Effendi Syafruddin, Mohd Faizal Ahmad

Life (Basel)· May 2023

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Interleukin-1 alpha and high mobility group box-1 secretion in polyinosinic:polycytidylic-induced colorectal cancer cells occur via RIPK1-dependent mechanism and participate in tumourigenesis.
Kim Jun Cheng, Elsa Haniffah Mejia Mohamed, Saiful Effendi Syafruddin, Zaridatul Aini Ibrahim

J Cell Commun Signal· March 2023

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HOXA10 DNA Methylation Level in the Endometrium Women with Endometriosis: A Systematic Review.
Marjanu Hikmah Elias, Nurunnajah Lazim, Zulazmi Sutaji, Mohammad Azrai Abu, Abdul Kadir Abdul Karim, Saiful Effendi Syafruddin

Biology (Basel)· March 2023

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Cancer Cell-Derived PDGFB Stimulates mTORC1 Activation in Renal Carcinoma.
Asmaa Y Abuhamad, Nurul Nadia Mohamad Zamberi, Sakari Vanharanta, Siti Nur Hasanah Mohd Yusuf, M Aiman Mohtar, Saiful Effendi Syafruddin

Int J Mol Sci· March 2023

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Whole genome sequencing of Malaysian colorectal cancer patients reveals specific druggable somatic mutations.
Ryia Illani Mohd Yunos, Nurul-Syakima Ab Mutalib, Jia-Shiun Khoo, Sazuita Saidin, Muhiddin Ishak, Saiful Effendi Syafruddin

Front Mol Biosci· February 2023

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Functions and mechanisms of protein disulfide isomerase family in cancer emergence.
Nisa Syakila A Rahman, Syazalina Zahari, Saiful Effendi Syafruddin, Mohd Firdaus-Raih, Teck Yew Low

Cell Biosci· August 2022

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The renal lineage factor PAX8 controls oncogenic signalling in kidney cancer.
Saroor A Patel, Shoko Hirosue, Paulo Rodrigues, Erika Vojtasova, Emma K Richardson, Saiful E Syafruddin

Nature· June 2022

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Reverting Mutation in Breast Cancer Cells: Prime Editing Workflow and Technical Considerations.
Asmaa Y Abuhamad, Nurul Nadia Mohamad Zamberi, Ling Sheen, Safaa M Naes, Siti Nur Hasanah Mohd Yusuf, Saiful Effendi Syafruddin

Cells· May 2022

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Short open reading frames (sORFs) and microproteins: an update on their identification and validation measures.
Alyssa Zi-Xin Leong, Pey Yee Lee, M Aiman Mohtar, Saiful Effendi Syafruddin, Yuh-Fen Pung

J Biomed Sci· March 2022

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