Publications by authors named "Sakthi Rajendran"

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An Isoform-Specific RUNX1C-BTG2 Axis Governs AML Quiescence and Chemoresistance.
Cuijuan Han, Zhiping Zhang, Edie I Crosse, Sogand Sajedi, Bin Lu, Sakthi Harini Rajendran

Blood Cancer Discov· September 2025

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Whole tissue spatial cellular analysis reveals increased macrophage infiltration in pancreata of autoantibody positive donors and patients with type 1 diabetes.
Estefania Quesada-Masachs, Samuel Zilberman, Tiffany Chu, Sara McArdle, William B Kiosses, Sakthi Rajendran

bioRxiv· September 2025

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The CCR6-CCL20 Axis Promotes Regulatory T-cell Glycolysis and Immunosuppression in Tumors.
Ayush Pant, Aanchal Jain, Yiyun Chen, Kisha Patel, Laura Saleh, Sakthi Rajendran

Cancer Immunol Res· November 2024

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Primary murine high-grade glioma cells derived from RCAS/tv-a diffuse glioma model reprogram naive T cells into immunosuppressive regulatory T lymphocytes.
Alessandro Canella, Mykyta Artomov, Aleksandr Ukhatov, Sakthi Rajendran, Phillip Perez

Mol Ther Oncol· September 2024

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Genetically modified IL2 bone-marrow-derived myeloid cells reprogram the glioma immunosuppressive tumor microenvironment.
Alessandro Canella, Matthew Nazzaro, Sakthi Rajendran, Claire Schmitt, Abigail Haffey

Cell Rep· August 2023

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Editorial: Decoding novel therapeutic targets, biomarkers, and drug development strategies against neurodegenerative disorders-A multi-omics approach.
E Srinivasan, Siranjeevi Nagaraj, Sakthi Rajendran, R Rajasekaran

Front Comput Neurosci· June 2023

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Single-cell RNA sequencing reveals immunosuppressive myeloid cell diversity during malignant progression in a murine model of glioma.
Sakthi Rajendran, Yang Hu, Alessandro Canella, Clayton Peterson, Amy Gross

Cell Rep· March 2023

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Myeloid cell heterogeneity in the tumor microenvironment and therapeutic implications for childhood central nervous system (CNS) tumors.
Sujay Kalathoor, Sakthi Rajendran, Alessandro Canella, Raju Raval, Timothy P Cripe

J Neuroimmunol· January 2023

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Developing antisense oligonucleotides for a mutation-induced, ultra-rare neurological disorder using patient-derived cellular models.
Luis A Williams, David J Gerber, Amy Elder, Wei Chou Tseng, Valeriya Baru, Sakthi H Rajendran

Mol Ther Nucleic Acids· September 2022

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Upregulation of HLA class II in pancreatic beta cells from organ donors with type 1 diabetes.
Estefania Quesada-Masachs, Samuel Zilberman, Sakthi Rajendran, Tiffany Chu, Sara McArdle

Diabetologia· February 2022

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IL-17 is expressed on beta and alpha cells of donors with type 1 and type 2 diabetes.
Sakthi Rajendran, Estefania Quesada-Masachs, Samuel Zilberman, Madeleine Graef, William B Kiosses

J Autoimmun· September 2021

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New Insights Into the Role of Autoreactive CD8 T Cells and Cytokines in Human Type 1 Diabetes.
Christine Bender, Sakthi Rajendran, Matthias G von Herrath

Front Endocrinol (Lausanne)· May 2021

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HLA class I hyper-expression unmasks beta cells but not alpha cells to the immune system in pre-diabetes.
Mehdi A Benkahla, Somayeh Sabouri, William B Kiosses, Sakthi Rajendran, Estefania Quesada-Masachs

J Autoimmun· May 2021

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IL-4R is expressed on alpha and beta cells of human pancreata.
Sakthi Rajendran, Madeleine Graef, Tiffany Chu, Matthias von Herrath

Clin Immunol· May 2020

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IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes.
Sakthi Rajendran, Florence Anquetil, Estefania Quesada-Masachs, Madeleine Graef, Nathaly Gonzalez

Clin Immunol· February 2020

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Epstein-Barr virus-encoded LMP1 induces ectopic CD137 expression on Hodgkin and Reed-Sternberg cells via the PI3K-AKT-mTOR pathway.
Sneha Priya Aravinth, Sakthi Rajendran, Yating Li, Meihui Wu, Anna Hiu Yi Wong

Leuk Lymphoma· November 2019

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Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells.
Sakthi Rajendran, Yating Li, Evelyn Ngoh, Hiu Yi Wong, Man Si Cheng

Front Oncol· September 2019

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Design and demonstration of an intracortical probe technology with tunable modulus.
Dustin M Simon, Hamid Charkhkar, Conan St John, Sakthi Rajendran, Tong Kang

J Biomed Mater Res A· January 2017

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CD137 signaling in Hodgkin and Reed-Sternberg cell lines induces IL-13 secretion, immune deviation and enhanced growth.
Sakthi Rajendran, Weng Tong Ho, Herbert Schwarz

Oncoimmunology· June 2016

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CD137 and CD137L signals are main drivers of type 1, cell-mediated immune responses.
Bhushan Dharmadhikari, Meihui Wu, Nur Sharalyn Abdullah, Sakthi Rajendran, Nur Diana Ishak

Oncoimmunology· April 2016

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