Publications by authors named "Salam Assi"

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Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia.
Shan Lin, Michael Kotliar, Sushmitha Vallabh, Anetta Ptasinska, Salam A Assi

Blood Adv· February 2025

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Gene regulation in t(6;9) DEK::NUP214 Acute Myeloid Leukemia resembles that of FLT3-ITD/NPM1 Acute Myeloid Leukemia but with an altered HOX/MEIS axis.
Sandeep Potluri, Sophie G Kellaway, Daniel J L Coleman, Peter Keane, Maria Rosaria Imperato, Salam A Assi

Leukemia· February 2024

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Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth.
Sophie G Kellaway, Sandeep Potluri, Peter Keane, Helen J Blair, Luke Ames, Salam A Assi

Nat Commun· February 2024

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Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Daniel J L Coleman, Peter Keane, Rosario Luque-Martin, Paulynn S Chin, Helen Blair, Salam A Assi

Cell Rep· December 2023

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Transcriptional reprogramming by mutated IRF4 in lymphoma.
Nikolai Schleussner, Pierre Cauchy, Vedran Franke, Maciej Giefing, Oriol Fornes, Salam A Assi

Nat Commun· November 2023

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Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth.
Daniel J L Coleman, Peter Keane, Rosario Luque-Martin, Paulynn S Chin, Helen Blair, Salam A Assi

bioRxiv· July 2023

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Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia.
Assunta Adamo, Paulynn Chin, Peter Keane, Salam A Assi, Sandeep Potluri

Leukemia· January 2023

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Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia.
Ricky Tirtakusuma, Katarzyna Szoltysek, Paul Milne, Vasily V Grinev, Anetta Ptasinska, Salam A Assi

Blood· October 2022

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PLCG1 is required for AML1-ETO leukemia stem cell self-renewal.
Tina M Schnoeder, Adrian Schwarzer, Ashok Kumar Jayavelu, Chen-Jen Hsu, Joanna Kirkpatrick, Salam A Assi

Blood· February 2022

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Isoform-specific and signaling-dependent propagation of acute myeloid leukemia by Wilms tumor 1.
Sandeep Potluri, Salam A Assi, Paulynn S Chin, Dan J L Coleman, Anna Pickin

Cell Rep· April 2021

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RUNX1/RUNX1T1 mediates alternative splicing and reorganises the transcriptional landscape in leukemia.
Vasily V Grinev, Farnaz Barneh, Ilya M Ilyushonak, Sirintra Nakjang, Job Smink, Salam A Assi

Nat Commun· January 2021

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RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) acute myeloid leukemia.
Paulynn Suyin Chin, Salam A Assi, Anetta Ptasinska, Maria Rosaria Imperato, Peter N Cockerill

Exp Hematol· December 2020

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Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets.
M S Vijayabaskar, Debbie K Goode, Nadine Obier, Monika Lichtinger, Amber M L Emmett, Salam A Assi

PLoS Comput Biol· November 2019

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RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction.
Anetta Ptasinska, Anna Pickin, Salam A Assi, Paulynn Suyin Chin, Luke Ames

Cell Rep· November 2019

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RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction.
Anetta Ptasinska, Anna Pickin, Salam A Assi, Paulynn Suyin Chin, Luke Ames

Cell Rep· September 2019

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Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma.
Benjamin Edginton-White, Pierre Cauchy, Salam A Assi, Sylvia Hartmann, Arthur G Riggs

Leukemia· June 2019

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Rewiring of the Transcription Factor Network in Acute Myeloid Leukemia.
Salam A Assi, Constanze Bonifer, Peter N Cockerill

Cancer Inform· June 2019

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The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.
Natalia Martinez-Soria, Lynsey McKenzie, Julia Draper, Anetta Ptasinska, Hasan Issa, Salam Assi

Cancer Cell· April 2019

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Subtype-specific regulatory network rewiring in acute myeloid leukemia.
Salam A Assi, Maria Rosaria Imperato, Daniel J L Coleman, Anna Pickin, Sandeep Potluri

Nat Genet· January 2019

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The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.
Natalia Martinez-Soria, Lynsey McKenzie, Julia Draper, Anetta Ptasinska, Hasan Issa, Salam Assi

Cancer Cell· October 2018

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The Co-operation of RUNX1 with LDB1, CDK9 and BRD4 Drives Transcription Factor Complex Relocation During Haematopoietic Specification.
Jane Gilmour, Salam A Assi, Laura Noailles, Monika Lichtinger, Nadine Obier

Sci Rep· July 2018

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C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia.
Justin Loke, Paulynn Suyin Chin, Peter Keane, Anna Pickin, Salam A Assi

Blood Adv· February 2018

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A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program.
Shan Lin, Anetta Ptasinska, Xiaoting Chen, Mahesh Shrestha, Salam A Assi

Blood· September 2017

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LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage.
Vesna S Stanulovic, Pierre Cauchy, Salam A Assi, Maarten Hoogenkamp

Nucleic Acids Res· September 2017

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RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML.
Justin Loke, Salam A Assi, Maria Rosaria Imperato, Anetta Ptasinska, Pierre Cauchy

Cell Rep· May 2017

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