Publications by authors named "Sam Lockhart"

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Rare Variants in HTRA1, SGTB, and RBM12 Confer Risk of Atherosclerotic Cardiovascular Disease Independent of Traditional Cardiovascular Risk Factors.
Sam M Lockhart, Anuradhika Puri, Yajie Zhao, Vladimir Saudek, Eugene J Gardner

Circ Genom Precis Med· December 2025

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Public Health.
Pablo Aguilar, Thomas Monroe Holland, Sam N Lockhart, Joseph C Masdeu, Lycia Tramujas Vasconcellos Neumann

Alzheimers Dement· December 2025

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Public Health.
Pablo Aguilar, Thomas Monroe Holland, Sam N Lockhart, Joseph C Masdeu, Lycia Tramujas Vasconcellos Neumann

Alzheimers Dement· December 2025

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Public Health.
Pablo Aguilar, Carmen M Colceriu, Alex López, María Franquesa-Mullerat, Sara E Zsadanyi, Sam N Lockhart

Alzheimers Dement· December 2025

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Public Health.
Theodore M DeConne, Cynthia Suerken, Megan E Lipford, Sam N Lockhart, Trey R Bateman

Alzheimers Dement· December 2025

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Effects of Rare Coding Variants in Severe Early-Onset Obesity Genes in the Population-Based UK Biobank Study.
Raina Y Jia, Sam Lockhart, Brian Y H Lam, Yajie Zhao, Katherine A Kentistou

J Clin Endocrinol Metab· October 2025

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Bidirectional Mendelian Randomization Indicates Causal Relationships Between Circulating Branched-Chain Amino Acids and Metabolic Health.
Raina Y Jia, Jian-Hua Chen, Sam Lockhart, Brian Y H Lam, Katherine A Kentistou

Diabetes· October 2025

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Population-scale gene-based analysis of whole-genome sequencing provides insights into metabolic health.
Yajie Zhao, Sam Lockhart, Jimmy Liu, Xihao Li, Adrian Cortes

Nat Genet· October 2025

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Plasma complement system markers and their association with cardiometabolic risk factors: an ethnic comparison of White European and Black African men.
Reuben M Reed, Wioleta M Zelek, B Paul Morgan, Gráinne Whelehan, Sam Lockhart

Am J Physiol Endocrinol Metab· April 2025

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Prone positioning is associated with increased insulin requirements in mechanically ventilated patients with COVID-19.
Harry Griffiths, Amy Cardwell, Max Richardson, Meg Barne, Bogdan Petrisor, Sam Lockhart

Sci Rep· November 2024

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Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health.
Sam M Lockhart, Milan Muso, Ilona Zvetkova, Brian Y H Lam, Alessandra Ferrari

Nat Metab· October 2024

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ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis.
Jérémie Gautheron, Solaf Elsayed, Valeria Pistorio, Sam Lockhart, Jamila Zammouri

Proc Natl Acad Sci U S A· June 2024

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Usefulness of Heat Map Explanations for Deep-Learning-Based Electrocardiogram Analysis.
Andrea M Storås, Ole Emil Andersen, Sam Lockhart, Roman Thielemann, Filip Gnesin

Diagnostics (Basel)· July 2023

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Author Correction: Proteogenomic links to human metabolic diseases.
Mine Koprulu, Julia Carrasco-Zanini, Eleanor Wheeler, Sam Lockhart, Nicola D Kerrison

Nat Metab· April 2023

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Proteogenomic links to human metabolic diseases.
Mine Koprulu, Julia Carrasco-Zanini, Eleanor Wheeler, Sam Lockhart, Nicola D Kerrison

Nat Metab· March 2023

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Endothelial Cell Insulin Signaling Regulates CXCR4 (C-X-C Motif Chemokine Receptor 4) and Limits Leukocyte Adhesion to Endothelium.
Thomas Rathjen, Britta Kunkemoeller, Carly T Cederquist, Xuanchun Wang, Sam M Lockhart

Arterioscler Thromb Vasc Biol· July 2022

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The transcriptional coregulator CITED2 suppresses expression of IRS-2 and impairs insulin signaling in endothelial cells.
Britta Kunkemoeller, Kuangyang Chen, Sam M Lockhart, Xuanchun Wang, Christian Rask-Madsen

Am J Physiol Endocrinol Metab· August 2021

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The excess insulin requirement in severe COVID-19 compared to non-COVID-19 viral pneumonitis is related to the severity of respiratory failure and pre-existing diabetes.
Sam M Lockhart, Harry Griffiths, Bogdan Petrisor, Ammara Usman, Julia Calvo-Latorre

Endocrinol Diabetes Metab· July 2021

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When Two Pandemics Meet: Why Is Obesity Associated with Increased COVID-19 Mortality?
Sam M Lockhart, Stephen O'Rahilly

Med· December 2020

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ACE inhibition and cardiometabolic risk factors, lung and gene expression, and plasma ACE2 levels: a Mendelian randomization study.
Dipender Gill, Marios Arvanitis, Paul Carter, Ana I Hernández Cordero, Brian Jo, Sam M Lockhart

R Soc Open Sci· November 2020

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A Survey of Patient's Perceptions and Proposed Provision of a 'Patient Portal' in Endocrine Outpatients.
Sam Lockhart, Ian Wallace, Ailish Nugent, Neil Black, Michael Quinn

Ulster Med J· September 2019

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Diabetes distress, illness perceptions and glycaemic control in adults with type 2 diabetes.
Kelly Martinez, Sam Lockhart, Mark Davies, John R Lindsay, Martin Dempster

Psychol Health Med· February 2018

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Diabetes distress: understanding the hidden struggles of living with diabetes and exploring intervention strategies.
Emma Berry, Sam Lockhart, Mark Davies, John R Lindsay, Martin Dempster

Postgrad Med J· May 2015

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