Publications by authors named "Samar Tawfik"

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New phenylpiperazine-thiazolidine-2,4-dione hybrids targeting MAO inhibition: Synthesis, biological evaluation, kinetic study and in silico insights.
Lamiaa O El-Halaby, Mohammad M Al-Sanea, Abdullah A Elgazar, Samar S Tawfik, Abdelrahman Hamdi

Bioorg Med Chem· April 2025

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Design, Synthesis, Biological Evaluation and Molecular Docking Study of New 1,3,4-Thiadiazole-Based Compounds as EGFR Inhibitors.
Marwa I Serag, Samar S Tawfik, Hassan M Eisa, Sahar M I Badr

Drug Dev Res· February 2025

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Design, Synthesis and Molecular Docking of New Thieno[2,3‑d]Pyrimidin-4-One Derivatives as Dual EGFR and FGFR Inhibitors.
Sara Sultan, Samar S Tawfik, Khalid B Selim, Magda N A Nasr

Drug Dev Res· February 2025

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Harnessing potential COX-2 engagement for boosting anticancer activity of substituted 2-mercapto-4(3H)-quinazolinones with promising EGFR/VEGFR-2 inhibitory activities.
Abdelrahman Hamdi, Samar S Tawfik, Ahmed R Ali, Wafaa A Ewes, Abdullah Haikal

Bioorg Chem· December 2024

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Design, synthesis, and and biological evaluation of triazolopyrimidine hybrids as multitarget directed anticancer agents.
Heba A Adawy, Samar S Tawfik, Abdullah A Elgazar, Khalid B Selim, Fatma E Goda

RSC Adv· November 2024

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Design, Synthesis, Pharmacological Evaluation of Quinazolin-4(3)-Ones Bearing Urea Functionality as Potential VEGFR-2 Inhibitors.
Mohammad M Al-Sanea, Hani M Hafez, Ahmed A B Mohamed, Hamed W El-Shafey, Abdullah A Elgazar, Samar S Tawfik

Drug Des Devel Ther· November 2024

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Unveiling new thiazole-clubbed piperazine derivatives as multitarget anti-AD: Design, synthesis, and in silico studies.
Eman E Nasr, Samar S Tawfik, Mohammed A M Massoud, Amany S Mostafa

Arch Pharm (Weinheim)· September 2024

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-Alkylated quinazolin-4(3)-ones as dual EGFR/VEGFR-2 kinases inhibitors: design, synthesis, anticancer evaluation and docking study.
Samar S Tawfik, Abdelrahman Hamdi, Ahmed R Ali, Abdullah A Elgazar, Hamed W El-Shafey

RSC Adv· August 2024

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Identification of Benzothiazoles Bearing 1,3,4-Thiadiazole as Antiproliferative Hybrids Targeting VEGFR-2 and BRAF Kinase: Design, Synthesis, BIO Evaluation and In Silico Study.
Wafaa A Ewes, Samar S Tawfik, Aya M Almatary, Mashooq Ahmad Bhat, Hamed W El-Shafey

Molecules· July 2024

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New oxadiazole and pyrazoline derivatives as anti-proliferative agents targeting EGFR-TK: design, synthesis, biological evaluation and molecular docking study.
Marwa I Serag, Samar S Tawfik, Sahar M I Badr, Hassan M Eisa

Sci Rep· March 2024

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Identification of new benzimidazole-triazole hybrids as anticancer agents: multi-target recognition, and studies.
Dina I A Othman, Abdelrahman Hamdi, Samar S Tawfik, Abdullah A Elgazar, Amany S Mostafa

J Enzyme Inhib Med Chem· December 2023

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New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and study.
Mohammad M Al-Sanea, Abdelrahman Hamdi, Ahmed A B Mohamed, Hamed W El-Shafey, Mahmoud Moustafa, Samar S Tawfik

J Enzyme Inhib Med Chem· December 2023

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Benzimidazole-based protein kinase inhibitors: Current perspectives in targeted cancer therapy.
Alaa M Ali, Samar S Tawfik, Amany S Mostafa, Mohammed A M Massoud

Chem Biol Drug Des· November 2022

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Supramolecular Self-Assembly Mediated by Multiple Hydrogen Bonds and the Importance of C-S···N Chalcogen Bonds in '-(Adamantan-2-ylidene)hydrazide Derivatives.
Lamya H Al-Wahaibi, Karthick Vishal Asokan, Nora H Al-Shaalan, Samar S Tawfik, Hanan M Hassan

ACS Omega· March 2022

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Potential health risk assessment of some bioaccumulated metals in Nile tilapia (Oreochromis niloticus) cultured in Kafr El-Shaikh farms, Egypt.
Nashwa A Shaaban, Samar Tawfik, Wael El-Tarras, Tamer El-Sayed Ali

Environ Res· September 2021

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1,3,4-Oxadiazole -Mannich Bases: Synthesis, Antimicrobial, and Anti-Proliferative Activities.
Lamya H Al-Wahaibi, Ahmed A B Mohamed, Samar S Tawfik, Hanan M Hassan, Ali A El-Emam

Molecules· April 2021

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Probing the Effect of Halogen Substituents (Br, Cl, and F) on the Non-covalent Interactions in 1-(Adamantan-1-yl)-3-arylthiourea Derivatives: A Theoretical Study.
Lamya H Al-Wahaibi, Divya Sri Grandhi, Samar S Tawfik, Nora H Al-Shaalan, Mohammed A Elmorsy

ACS Omega· February 2021

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