Publications by authors named "Samara Singh"

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CREB Drives Acinar to Ductal Cells Reprogramming and Promotes Pancreatic Cancer Progression in Preclinical Models of Alcoholic Pancreatitis.
Supriya Srinivasan, Siddharth Mehra, Sudhakar Jinka, Anna Bianchi, Samara Singh

Cell Mol Gastroenterol Hepatol· November 2025

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CREB drives acinar cells to ductal reprogramming and promotes pancreatic cancer progression in preclinical models of alcoholic pancreatitis.
Supriya Srinivasan, Siddharth Mehra, Sudhakar Jinka, Anna Bianchi, Samara Singh

bioRxiv· July 2025

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IL-6/IL-12 superfamily of cytokines and regulatory lymphocytes play critical roles in the etiology and suppression of CNS autoimmune diseases.
Manoj Kumar Yadav, Samara P Singh, Charles E Egwuagu

Front Immunol· May 2025

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Microbial influences on severity and sex bias of systemic autoimmunity.
Jean Lee, Derek Reiman, Samara Singh, Anthony Chang, Laurence Morel

Immunol Rev· August 2024

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The Role of Myeloid Cells on the Development of Hepatic Metastases in Gastrointestinal Cancer.
Austin R Dosch, Mary P Martos, Samara Singh, Karishma Kodia, Nipun B Merchant

Gastro Hep Adv· August 2024

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Tumor Cell-Intrinsic p38 MAPK Signaling Promotes IL1α-Mediated Stromal Inflammation and Therapeutic Resistance in Pancreatic Cancer.
Samara P Singh, Austin R Dosch, Siddharth Mehra, Iago De Castro Silva, Anna Bianchi

Cancer Res· April 2024

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Remodeling of Stromal Immune Microenvironment by Urolithin A Improves Survival with Immune Checkpoint Blockade in Pancreatic Cancer.
Siddharth Mehra, Vanessa T Garrido, Austin R Dosch, Purushottam Lamichhane, Supriya Srinivasan, Samara P Singh

Cancer Res Commun· July 2023

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Cell-Autonomous Cxcl1 Sustains Tolerogenic Circuitries and Stromal Inflammation via Neutrophil-Derived TNF in Pancreatic Cancer.
Anna Bianchi, Iago De Castro Silva, Nilesh U Deshpande, Samara Singh, Siddharth Mehra

Cancer Discov· June 2023

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Overcoming Acquired Drug Resistance to Cancer Therapies through Targeted STAT3 Inhibition.
Sunanda Singh, Hector J Gomez, Shreya Thakkar, Samara P Singh, Ashutosh S Parihar

Int J Mol Sci· March 2023

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Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic Cancer.
Jashodeep Datta, Xizi Dai, Anna Bianchi, Iago De Castro Silva, Siddharth Mehra, Samara P Singh

Gastroenterology· December 2022

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Urolithin A attenuates severity of chronic pancreatitis associated with continued alcohol intake by inhibiting PI3K/AKT/mTOR signaling.
Siddharth Mehra, Supriya Srinivasan, Samara Singh, Zhiqun Zhou, Vanessa Garrido

Am J Physiol Gastrointest Liver Physiol· October 2022

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Distinct mechanisms of innate and adaptive immune regulation underlie poor oncologic outcomes associated with KRAS-TP53 co-alteration in pancreatic cancer.
Jashodeep Datta, Anna Bianchi, Iago De Castro Silva, Nilesh U Deshpande, Long Long Cao, Samara Singh

Oncogene· July 2022

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A Broad-Based Characterization of a Cell-Penetrating, Single Domain Camelid Bi-Specific Antibody Monomer That Targets STAT3 and KRAS Dependent Cancers.
Sunanda Singh, Genoveva Murillo, Justin Richner, Samara P Singh, Erica Berleth

Int J Mol Sci· July 2022

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Emerging Role of CREB in Epithelial to Mesenchymal Plasticity of Pancreatic Cancer.
Siddharth Mehra, Samara Singh, Nagaraj Nagathihalli

Front Oncol· June 2022

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Interleukin-1 signaling in solid organ malignancies.
Austin R Dosch, Samara Singh, Nagaraj S Nagathihalli, Jashodeep Datta, Nipun B Merchant

Biochim Biophys Acta Rev Cancer· January 2022

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Targeting Tumor-Stromal IL6/STAT3 Signaling through IL1 Receptor Inhibition in Pancreatic Cancer.
Austin R Dosch, Samara Singh, Xizi Dai, Siddharth Mehra, Iago De Castro Silva

Mol Cancer Ther· November 2021

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