Publications by authors named "Sameh A Youssef"

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Neurodegenerative Diseases: Pathogenesis and Preclinical Models for Translational Drug Discovery.
Laura Fusaro, Dinesh S Bangari, R Jeroen Pasterkamp, Javier Fernández-Ruiz, Sameh A Youssef

Toxicol Pathol· June 2025

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Navigating from cellular phenotypic screen to clinical candidate: selective targeting of the NLRP3 inflammasome.
Rosalie Matico, Karolien Grauwen, Dhruv Chauhan, Xiaodi Yu, Irini Abdiaj, Sameh A Youssef

EMBO Mol Med· January 2025

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Points to Consider From the ESTP Pathology 2.0 Working Group: Overview on Spatial Omics Technologies Supporting Drug Discovery and Development.
Kerstin Hahn, Bettina Amberg, Josep M Monné Rodriguez, Mieke Verslegers, Byunghak Kang, Sameh A Youssef

Toxicol Pathol· January 2025

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Rebalancing of mitochondrial homeostasis through an NAD-SIRT1 pathway preserves intestinal barrier function in severe malnutrition.
Catriona Ling, Christian J Versloot, Matilda E Arvidsson Kvissberg, Guanlan Hu, Nathan Swain, Sameh A Youssef

EBioMedicine· October 2023

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Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.
Esther Stroo, Leen Janssen, Olga Sin, Wytse Hogewerf, Mirjam Koster, Sameh A Youssef

Life Sci Alliance· July 2023

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Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice.
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Sameh A Youssef

Dis Model Mech· June 2023

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The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression.
Giorgia Benegiamo, Giacomo V G von Alvensleben, Sandra Rodríguez-López, Ludger J E Goeminne, Alexis M Bachmann, Sameh A Youssef

J Exp Med· April 2023

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DNAJB6b-enriched small extracellular vesicles decrease polyglutamine aggregation in and models of Huntington disease.
Bhagyashree S Joshi, Sameh A Youssef, Reinier Bron, Alain de Bruin, Harm H Kampinga

iScience· November 2021

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Ablation of liver results in an increased colonic mucus barrier in mice.
Noortje Ijssennagger, Kristel S van Rooijen, Stefanía Magnúsdóttir, José M Ramos Pittol, Ellen C L Willemsen, Sameh A Youssef

JHEP Rep· October 2021

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Acute systemic loss of Mad2 leads to intestinal atrophy in adult mice.
Klaske M Schukken, Yinan Zhu, Petra L Bakker, Mirjam H Koster, Liesbeth Harkema, Sameh A Youssef

Sci Rep· January 2021

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Molecular pathways of senescence regulate placental structure and function.
Hilah Gal, Marina Lysenko, Sima Stroganov, Ezra Vadai, Sameh A Youssef

EMBO J· August 2020

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C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the /LIN28B circuit in mice.
Tobias Ackermann, Götz Hartleben, Christine Müller, Guido Mastrobuoni, Marco Groth, Sameh A Youssef

Commun Biol· May 2020

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and act redundantly for ovarian-to-testicular fate reprogramming in the absence of in mouse sex reversals.
Nainoa Richardson, Isabelle Gillot, Elodie P Gregoire, Sameh A Youssef, Dirk de Rooij

Elife· May 2020

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MyD88-dependent signaling in non-parenchymal cells promotes liver carcinogenesis.
Antje Mohs, Nadine Kuttkat, Tobias Otto, Sameh A Youssef, Alain De Bruin

Carcinogenesis· April 2020

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Molecular pathways of senescence regulate placental structure and function.
Hilah Gal, Marina Lysenko, Sima Stroganov, Ezra Vadai, Sameh A Youssef

EMBO J· September 2019

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Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice.
Khaled Aziz, Jazeel F Limzerwala, Ines Sturmlechner, Erin Hurley, Cheng Zhang, Sameh A Youssef

Gastroenterology· July 2019

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LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats.
Lori W E van der Schoor, Christian V Hulzebos, Martijn H van Faassen, Ido P Kema, Alain de Bruin, Sameh A Youssef

Pediatr Res· June 2019

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Atypical E2f functions are critical for pancreas polyploidization.
Ramadhan B Matondo, Eva Moreno, Mathilda J M Toussaint, Peter C J Tooten, Saskia C van Essen, Sameh A Youssef

PLoS One· February 2018

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Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.
Sandra Segura-Bayona, Philip A Knobel, Helena González-Burón, Sameh A Youssef, Aida Peña-Blanco

Cell Death Differ· November 2017

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CDK10 Mutations in Humans and Mice Cause Severe Growth Retardation, Spine Malformations, and Developmental Delays.
Christian Windpassinger, Juliette Piard, Carine Bonnard, Majid Alfadhel, Shuhui Lim, Sameh A Youssef

Am J Hum Genet· September 2017

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Intraductal cisplatin treatment in a -associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.
Jolien S de Groot, Paul J van Diest, Miranda van Amersfoort, Eva J Vlug, Xiaojuan Pan, Sameh A Youssef

Oncotarget· September 2017

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Functional role of CCL5/RANTES for HCC progression during chronic liver disease.
Antje Mohs, Nadine Kuttkat, Johanna Reißing, Henning Wolfgang Zimmermann, Roland Sonntag, Sameh A Youssef

J Hepatol· April 2017

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Modeling Dynamics and Function of Bone Marrow Cells in Mouse Liver Regeneration.
Elisa Pedone, Vlad-Aris Olteanu, Lucia Marucci, Maria Isabel Muñoz-Martin, Sameh A Youssef

Cell Rep· January 2017

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Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression.
Sathidpak Nantasanti, Mathilda J M Toussaint, Sameh A Youssef, Peter C J Tooten, Alain de Bruin

PLoS One· November 2016

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Full ablation of C9orf72 in mice causes immune system-related pathology and neoplastic events but no motor neuron defects.
Emma Sudria-Lopez, Max Koppers, Marina de Wit, Christiaan van der Meer, Henk-Jan Westeneng, Sameh A Youssef

Acta Neuropathol· July 2016

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