Publications by authors named "Sami Alakurtti"

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Identification of Novel HBV/HDV Entry Inhibitors by Pharmacophore- and QSAR-Guided Virtual Screening.
Michael Kirstgen, Simon Franz Müller, Kira Alessandra Alicia Theresa Lowjaga, Nora Goldmann, Felix Lehmann, Sami Alakurtti

Viruses· July 2021

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Leishmanicidal Activity of Betulin Derivatives in Effect on Plasma and Mitochondrial Membrane Potential, and Macrophage Nitric Oxide and Superoxide Production.
Wilmer Alcazar, Sami Alakurtti, Maritza Padrón-Nieves, Maija Liisa Tuononen, Noris Rodríguez

Microorganisms· February 2021

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Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids.
Michael Kirstgen, Kira Alessandra Alicia Theresa Lowjaga, Simon Franz Müller, Nora Goldmann, Felix Lehmann, Sami Alakurtti

Sci Rep· December 2020

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Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo.
Ilari Mäki-Opas, Mari Hämäläinen, Lauri J Moilanen, Raisa Haavikko, Tiina J Ahonen, Sami Alakurtti

ACS Chem Neurosci· June 2019

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Biotransformation of Cyclodextrine-Complexed Semisynthetic Betulin Derivatives by Plant Cells.
Suvi T Häkkinen, Heli Nygren, Natalia Maiorova, Raisa Haavikko, Sami Alakurtti

Planta Med· July 2018

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Suberin Fatty Acids from Outer Birch Bark: Isolation and Physical Material Characterization.
Jyrki Heinämäki, Minni M Pirttimaa, Sami Alakurtti, H Pauliina Pitkänen, Heimo Kanerva

J Nat Prod· April 2017

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Development of Suberin Fatty Acids and Chloramphenicol-Loaded Antimicrobial Electrospun Nanofibrous Mats Intended for Wound Therapy.
Ingrid Tamm, Jyrki Heinämäki, Ivo Laidmäe, Liisi Rammo, Urve Paaver, Sami Alakurtti

J Pharm Sci· March 2016

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Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development.
Ville Härmä, Raisa Haavikko, Johannes Virtanen, Ilmari Ahonen, Hannu-Pekka Schukov, Sami Alakurtti

PLoS One· February 2016

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Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi.
Minni Pirttimaa, Abedelmajeed Nasereddin, Dmitry Kopelyanskiy, Marcel Kaiser, Jari Yli-Kauhaluoma, Sami Alakurtti

J Nat Prod· February 2016

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Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo.
Mirka Laavola, Raisa Haavikko, Mari Hämäläinen, Tiina Leppänen, Riina Nieminen, Sami Alakurtti

J Nat Prod· February 2016

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Screening and characterisation of antimicrobial properties of semisynthetic betulin derivatives.
Shafiul Haque, Dorota A Nawrot, Sami Alakurtti, Leo Ghemtio, Jari Yli-Kauhaluoma

PLoS One· December 2015

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Suberin fatty acids isolated from outer birch bark improve moisture barrier properties of cellulose ether films intended for tablet coatings.
Jyrki Heinämäki, Anna Halenius, Maaja Paavo, Sami Alakurtti, Pauliina Pitkänen

Int J Pharm· July 2015

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Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12).
Teija Parkkari, Raisa Haavikko, Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Sami Alakurtti

PLoS One· January 2015

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Betulin derivatives impair Leishmania braziliensis viability and host-parasite interaction.
Wilmer Alcazar, Adrian Silva López, Sami Alakurtti, Maija-Liisa Tuononen, Jari Yli-Kauhaluoma

Bioorg Med Chem· November 2014

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Direct assembly of 2-oxazolidinones by chemical fixation of carbon dioxide.
Teemu Niemi, Jesus E Perea-Buceta, Israel Fernández, Sami Alakurtti, Erika Rantala

Chemistry· July 2014

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Toxicity of betulin derivatives and in vitro effect on promastigotes and amastigotes of Leishmania infantum and L. donovani.
León Wert, Sami Alakurtti, María Jesús Corral, Sebastián Sánchez-Fortún, Jari Yli-Kauhaluoma

J Antibiot (Tokyo)· July 2011

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Synthesis and evaluation of library of betulin derivatives against the botulinum neurotoxin A protease.
Peter Šilhár, Sami Alakurtti, Kateřina Čapková, Feng Xiaochuan, Charles B Shoemaker

Bioorg Med Chem Lett· April 2011

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Inhibitory effect of the natural product betulin and its derivatives against the intracellular bacterium Chlamydia pneumoniae.
Olli Salin, Sami Alakurtti, Leena Pohjala, Antti Siiskonen, Viola Maass

Biochem Pharmacol· October 2010

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Anti-leishmanial activity of betulin derivatives.
Sami Alakurtti, Pia Bergström, Nina Sacerdoti-Sierra, Charles L Jaffe, Jari Yli-Kauhaluoma

J Antibiot (Tokyo)· March 2010

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Synthesis and anti-leishmanial activity of heterocyclic betulin derivatives.
Sami Alakurtti, Tuomo Heiska, Alexandros Kiriazis, Nina Sacerdoti-Sierra, Charles L Jaffe

Bioorg Med Chem· February 2010

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Betulin-derived compounds as inhibitors of alphavirus replication.
Leena Pohjala, Sami Alakurtti, Tero Ahola, Jari Yli-Kauhaluoma, Päivi Tammela

J Nat Prod· November 2009

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Regioselective sulfonation of dopamine by SULT1A3 in vitro provides a molecular explanation for the preponderance of dopamine-3-O-sulfate in human blood circulation.
Katriina Itäaho, Sami Alakurtti, Jari Yli-Kauhaluoma, Jyrki Taskinen, Michael W H Coughtrie

Biochem Pharmacol· August 2007

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Pharmacological properties of the ubiquitous natural product betulin.
Sami Alakurtti, Taru Mäkelä, Salme Koskimies, Jari Yli-Kauhaluoma

Eur J Pharm Sci· September 2006

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