Publications by authors named "Samir Hamdan"

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Real-time imaging of rotation during synthesis by the replisome.
Thomas M Retzer, Lional T Rajappa, Masateru Takahashi, Samir M Hamdan, Karl E Duderstadt

Sci Adv· January 2026

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Structure of the human CTF18-RFC clamp loader bound to PCNA.
Giuseppina R Briola, Muhammad Tehseen, Amani Al-Amodi, Grace Young, Ammar U Danazumi, Samir M Hamdan

bioRxiv· November 2025

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Structural dynamics of DNA unwinding by a replicative helicase.
Taha Shahid, Ammar U Danazumi, Muhammad Tehseen, Lubna Alhudhali, Alice R Clark, Samir M Hamdan

Nature· May 2025

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Real-time imaging of rotation during synthesis by the replisome.
Thomas M Retzer, Lional T Rajappa, Masateru Takahashi, Samir M Hamdan, Karl E Duderstadt

bioRxiv· April 2025

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Molecular architecture and functional dynamics of the pre-incision complex in nucleotide excision repair.
Jina Yu, Chunli Yan, Tanmoy Paul, Lucas Brewer, Susan E Tsutakawa, Samir M Hamdan

Nat Commun· October 2024

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Revised mechanism of hydroxyurea-induced cell cycle arrest and an improved alternative.
Alisa E Shaw, Mattias N Mihelich, Jackson E Whitted, Hannah J Reitman, Adam J Timmerman, Samir M Hamdan

Proc Natl Acad Sci U S A· October 2024

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Structure of Aquifex aeolicus lumazine synthase by cryo-electron microscopy to 1.42 Å resolution.
Christos G Savva, Mohamed A Sobhy, Alfredo De Biasio, Samir M Hamdan

IUCrJ· September 2024

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Single-molecule characterization of SV40 replisome and novel factors: human FPC and Mcm10.
Yujing Ouyang, Amani Al-Amodi, Muhammad Tehseen, Lubna Alhudhali, Afnan Shirbini, Samir M Hamdan

Nucleic Acids Res· August 2024

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Enantiocomplementary Asymmetric Reduction of 2-Haloacetophenones Using SADH: Synthesis of Enantiopure 2-Halo-1-arylethanols.
Muhammad Abdulrasheed, Auwal Eshi Sardauna, Mouheddin T Alhaffar, Masateru Takahashi, Etsuko Takahashi, Samir M Hamdan

ACS Omega· August 2024

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Severe Combined Immunodeficiency from a Homozygous DNA Ligase 1 Mutant with Reduced Catalytic Activity but Increased Ligation Fidelity.
Huda Alajlan, Vlad-Stefan Raducanu, Yossef Lopez de Los Santos, Muhammad Tehseen, Hibah Alruwaili, Samir M Hamdan

J Clin Immunol· June 2024

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Modulation of the microhomology-mediated end joining pathway suppresses large deletions and enhances homology-directed repair following CRISPR-Cas9-induced DNA breaks.
Baolei Yuan, Chongwei Bi, Yeteng Tian, Jincheng Wang, Yiqing Jin, Samir Hamdan

BMC Biol· April 2024

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An open-source, automated, and cost-effective platform for COVID-19 diagnosis and rapid portable genomic surveillance using nanopore sequencing.
Gerardo Ramos-Mandujano, Raik Grünberg, Yingzi Zhang, Chongwei Bi, Francisco J Guzmán-Vega, Samir M Hamdan

Sci Rep· November 2023

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Functional hierarchy of PCNA-interacting motifs in DNA processing enzymes.
Samir M Hamdan, Alfredo De Biasio

Bioessays· June 2023

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Efficient in planta production of amidated antimicrobial peptides that are active against drug-resistant ESKAPE pathogens.
Shahid Chaudhary, Zahir Ali, Muhammad Tehseen, Evan F Haney, Aarón Pantoja-Angles, Samir M Hamdan

Nat Commun· March 2023

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A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair.
Amer Bralić, Muhammad Tehseen, Mohamed A Sobhy, Chi-Lin Tsai, Lubna Alhudhali, Samir M Hamdan

Nucleic Acids Res· February 2023

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Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing.
Liu He, Rebecca Lever, Andrew Cubbon, Muhammad Tehseen, Tabitha Jenkins, Samir M Hamdan

Nucleic Acids Res· February 2023

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Rapid single-molecule characterisation of enzymes involved in nucleic-acid metabolism.
Stefan H Mueller, Lucy J Fitschen, Afnan Shirbini, Samir M Hamdan, Lisanne M Spenkelink

Nucleic Acids Res· January 2023

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Author Correction: Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Kerry Blair, Muhammad Tehseen, Vlad-Stefan Raducanu, Taha Shahid, Claudia Lancey, Samir M Hamdan

Nat Commun· January 2023

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Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Kerry Blair, Muhammad Tehseen, Vlad-Stefan Raducanu, Taha Shahid, Claudia Lancey, Samir M Hamdan

Nat Commun· December 2022

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Mechanistic investigation of human maturation of Okazaki fragments reveals slow kinetics.
Vlad-Stefan Raducanu, Muhammad Tehseen, Amani Al-Amodi, Luay I Joudeh, Alfredo De Biasio, Samir M Hamdan

Nat Commun· November 2022

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Cryo-electron structures of the extreme thermostable enzymes Sulfur Oxygenase Reductase and Lumazine Synthase.
Mohamed A Sobhy, Lingyun Zhao, Dalaver Anjum, Ali Behzad, Masateru Takahashi, Samir Hamdan

PLoS One· October 2022

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Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano, Mengge Wang, Samir Hamdan

Nat Commun· September 2022

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Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing.
Baolei Yuan, Xuan Zhou, Keiichiro Suzuki, Gerardo Ramos-Mandujano, Mengge Wang, Samir Hamdan

Nat Commun· June 2022

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Unpaired nucleotides on the stem of microRNA precursor are important for precise cleavage by Dicer-like 1 in Arabidopsis.
Rikako Hirata, Tomoya Makabe, Kei-Ichiro Mishiba, Nozomu Koizumi, Samir M Hamdan

Genes Cells· April 2022

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Decoding Cancer Variants of Unknown Significance for Helicase-Nuclease-RPA Complexes Orchestrating DNA Repair During Transcription and Replication.
Susan E Tsutakawa, Albino Bacolla, Panagiotis Katsonis, Amer Bralić, Samir M Hamdan

Front Mol Biosci· December 2021

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