Publications by authors named "Samir M Awad"

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Development of nifedipine isosteres: an integrated approach to the design, synthesis, and biological assessment of calcium channel blockers.
Yasser M Zohny, Samir M Awad, Omar Alsaidan, Maha A Rabie

Front Chem· May 2025

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Design, synthesis, molecular modelling and biological evaluation of novel 6-amino-5-cyano-2-thiopyrimidine derivatives as potent anticancer agents against leukemia and apoptotic inducers.
Naglaa M Ahmed, Mosaad S Mohamed, Samir M Awad, Rania H Abd El-Hameed, Neama A Abd El-Tawab

J Enzyme Inhib Med Chem· December 2024

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Synthesis, Anti-Cancer Activity, Cell Cycle Arrest, Apoptosis Induction, and Docking Study of Fused Benzo[]chromeno[2,3-]pyrimidine on Human Breast Cancer Cell Line MCF-7.
Zainab M Khoder, Mosaad S Mohamed, Samir M Awad, Amal F Gharib, Omnia Aly

Molecules· October 2024

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Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells.
Rania H Abd El-Hameed, Mosaad S Mohamed, Samir M Awad, Bardes B Hassan, Marwa Abd El-Fattah Khodair

J Enzyme Inhib Med Chem· December 2023

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Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Pyrimidine Derivatives as Potential Calcium Channel Blockers.
Yasser M Zohny, Samir M Awad, Maha A Rabie, Omar Awad Alsaidan

Molecules· June 2023

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Novel 2-Thiouracil-5-Sulfonamide Derivatives: Design, Synthesis, Molecular Docking, and Biological Evaluation as Antioxidants with 15-LOX Inhibition.
Naglaa M Ahmed, Ahmed H Lotfallah, Mohamed S Gaballah, Samir M Awad, Moustafa K Soltan

Molecules· February 2023

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Synthesis of Dihydropyrimidines: Isosteres of Nifedipine and Evaluation of Their Calcium Channel Blocking Efficiency.
Yasser M Zohny, Samir M Awad, Maha A Rabie, Omar A Al-Saidan

Molecules· January 2023

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Novel hit of DPP-4Is as promising antihyperglycemic agents with dual antioxidant/anti-inflammatory effects for type 2 diabetes with/without COVID-19.
Shahenda Mahgoub, Samar S Fatahala, Amira I Sayed, Hanaa B Atya, Mohamed F El-Shehry, Samir M Awad

Bioorg Chem· November 2022

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Design, synthesis, ADME, biological evaluation and molecular dynamic studies of natural and synthetic remedy of Herpes simplex virus type-1.
Suhad Sami Humadi, Samir Mohamed Awad, Ahmed Abd Elkader El-Rashedy, Mohamed Fathy El-Shehry

Pak J Pharm Sci· July 2022

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Synthesis and Evaluation of Cytotoxic Activity of Certain Benzo[h]chromene Derivatives.
Samir M Awad, Mosaad S Mohamed, Marwa Abd El-Fattah Khodair, Rania H Abd El-Hameed

Anticancer Agents Med Chem· December 2021

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Synthesis of Novel 2-Thiouracil-5-Sulfonamide Derivatives as Potent Inducers of Cell Cycle Arrest and CDK2A Inhibition Supported by Molecular Docking.
Samar S Fatahala, Amira I Sayed, Shahenda Mahgoub, Heba Taha, Mohamed-I Kotb El-Sayed, Samir M Awad

Int J Mol Sci· November 2021

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Synthesis and Evaluation of Some Uracil Nucleosides as Promising Anti-Herpes Simplex Virus 1 Agents.
Samir Mohamed Awad, Shima Mahmoud Ali, Yara Essam Mansour, Samar Said Fatahala

Molecules· May 2021

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Design, synthesis, molecular modelling and biological evaluation of novel 3-(2-naphthyl)-1-phenyl-1H-pyrazole derivatives as potent antioxidants and 15-Lipoxygenase inhibitors.
Sahar A Ali, Samir Mohamed Awad, Ahmed Mohammed Said, Shahenda Mahgoub, Heba Taha

J Enzyme Inhib Med Chem· December 2020

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Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity.
Hesham Haffez, Heba Taha, Maha A Rabie, Samir M Awad, Yasser M Zohny

Bioorg Chem· November 2020

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The Nrf2 Activator (DMF) and Covid-19: Is there a Possible Role?
Saif M Hassan, Mahmood J Jawad, Salam W Ahjel, Ram B Singh, Jaipaul Singh, Samir Mohamed Awad

Med Arch· April 2020

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Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Thiouracil Derivatives as Potential Antithyroid Agents.
Samir M Awad, Yasser M Zohny, Sahar A Ali, Shahenda Mahgoub, Ahmed M Said

Molecules· November 2018

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Synthesis and antimicrobial evaluation of some 6-aryl-5-cyano-2-thiouracil derivatives.
Mosaad Sayed Mohamed, Samir Mohamed Awad, Naglaa Mohamed Ahmed

Acta Pharm· June 2011

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Synthesis of certain pyrimidine derivatives as antimicrobial agents and anti-inflammatory agents.
Mosaad S Mohamed, Samir M Awad, Amira Ibrahim Sayed

Molecules· March 2010

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Synthesis and in vitro antitumor activity of new substituted thiopyrimidine acyclic nucleosides and their thioglycoside analogs.
Wael A El-Sayed, Aymn E Rashad, Samir M Awad, Mamdouh M Ali

Nucleosides Nucleotides Nucleic Acids· April 2009

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