Publications by authors named "Samuel D Saibil"

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Response to Immune Checkpoint Blockade is Enhanced in the Presence of Hematopoietic TET2 Inactivation.
Vincent Rondeau, Suraj Bansal, Marco M Buttigieg, Andy G X Zeng, Darryl Y Chan, Samuel D Saibil

Cancer Res· November 2025

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Protocol for halofuginone-mediated metabolic reprogramming of murine T cells via activation of the GCN2 pathway.
Meghan Kates, Michael St Paul, Pamela S Ohashi, Samuel D Saibil

STAR Protoc· October 2025

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LARP4-mediated hypertranslation drives T cell dysfunction in tumors.
Yi Liu, Haochen Ni, Jie Li, Jing Yang, Ivann Sekielyk, Samuel D Saibil

Nat Immunol· September 2025

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Author Correction: LARP4-mediated hypertranslation drives T cell dysfunction in tumors.
Yi Liu, Haochen Ni, Jie Li, Jing Yang, Ivann Sekielyk, Samuel D Saibil

Nat Immunol· September 2025

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Prognostic and Predictive Value of ctDNA for Metastatic Uveal Melanoma: A Systematic Review and Meta-Analysis.
Mariana Macambira Noronha, Luís Felipe Leite da Silva, Luiz Felipe Costa Almeida, Pedro Robson Costa Passos, Pedro Cotta Abrahão Reis, Samuel D Saibil

Pigment Cell Melanoma Res· September 2025

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Discordance between biochemical and histological severity in persistent immune checkpoint inhibitor induced liver injury.
Chloe Attree, Samuel D Saibil, Sandra Fischer, Morven Cunningham

BMJ Case Rep· August 2025

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Like a Complete Unknown: An Audit of the Quality of the Referrals to the Cancer of Unknown Primary Clinic at a Tertiary Care Centre.
Ian Hirsch, Jonah Teich, Khaled Abdulalem, Samuel D Saibil

Clin Pract· June 2025

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Immune Checkpoint Inhibitor-Induced Pancreatic Injury (ICI-PI) in Adult Cancer Patients: A Systematic Review and Meta-Analysis.
Cha Len Lee, Israt Jahan Riya, Ifrat Jahan Piya, Thiago Pimentel Muniz, Marcus Otho Butler, Samuel David Saibil

Cancers (Basel)· March 2025

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Female Oncofertility and Immune Checkpoint Blockade in Melanoma: Where Are We Today?
Cha Len Lee, Erika Martinez, Diego Malon Gimenez, Thiago Pimentel Muniz, Marcus Otho Butler, Samuel David Saibil

Cancers (Basel)· January 2025

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Characterization of innate lymphoid cell subsets infiltrating melanoma and epithelial ovarian tumors.
Douglas C Chung, Maryam Ghaedi, Kathrin Warner, Azin Sayad, Samuel D Saibil

Oncoimmunology· May 2024

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Reprogramming T-cell metabolism to enhance adoptive cell therapies.
Meghan Kates, Samuel D Saibil

Int Immunol· April 2024

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Ex vivo activation of the GCN2 pathway metabolically reprograms T cells, leading to enhanced adoptive cell therapy.
Michael St Paul, Samuel D Saibil, Meghan Kates, SeongJun Han, Scott C Lien

Cell Rep Med· March 2024

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The Role of Adjuvant Radiotherapy for the Treatment of Resected High-Risk Stage III Cutaneous Melanoma in the Era of Modern Systemic Therapies.
Seth Kibel, Nathan Kuehne, Mauricio Fernando Ribeiro, Thiago P Muniz, Xiang Y Ye, Samuel D Saibil

Cancers (Basel)· December 2023

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Immune Checkpoint Inhibitors in Advanced Cutaneous Squamous Cell Carcinoma: Real-World Experience from a Canadian Comprehensive Cancer Centre.
Erica C Koch Hein, Maysa Vilbert, Ian Hirsch, Mauricio Fernando Ribeiro, Thiago P Muniz, Samuel D Saibil

Cancers (Basel)· August 2023

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Analysis of the Circulating Metabolome of Patients with Cutaneous, Mucosal and Uveal Melanoma Reveals Distinct Metabolic Profiles with Implications for Response to Immunotherapy.
Maysa Vilbert, Erica C Koch, April A N Rose, Rob C Laister, Diana Gray, Samuel D Saibil

Cancers (Basel)· July 2023

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Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy.
Giselle M Boukhaled, Ramy Gadalla, Heidi J Elsaesser, Diala Abd-Rabbo, Rene Quevedo, Samuel D Saibil

Nat Immunol· August 2022

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Turnaround Times in Melanoma BRAF Testing and the Impact on the Initiation of Systemic Therapy at a Single Tertiary Care Cancer Center.
Diana Paola Arteaga Ceballos, Zaid Saeed-Kamil, Ian King, Tracy Stockley, Diane Liu, Samuel D Saibil

JCO Oncol Pract· May 2022

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Coenzyme A fuels T cell anti-tumor immunity.
Michael St Paul, Samuel D Saibil, SeongJun Han, Kavita Israni-Winger, Scott C Lien

Cell Metab· December 2021

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CANDIED: A Pan-Canadian Cohort of Immune Checkpoint Inhibitor-Induced Insulin-Dependent Diabetes Mellitus.
Thiago P Muniz, Daniel V Araujo, Kerry J Savage, Tina Cheng, Moumita Saha, Samuel D Saibil

Cancers (Basel)· December 2021

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Development of a Metastatic Uveal Melanoma Prognostic Score (MUMPS) for Use in Patients Receiving Immune Checkpoint Inhibitors.
Deirdre Kelly, April A N Rose, Thiago Pimentel Muniz, David Hogg, Marcus O Butler, Samuel D Saibil

Cancers (Basel)· July 2021

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Presumed complement-mediated, checkpoint inhibitor-induced, thrombotic microangiopathy in a patient with metastatic melanoma.
Thiago P Muniz, Christopher J Patriquin, Samuel D Saibil

BMJ Case Rep· July 2021

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Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition.
Aljosja Rogiers, Ines Pires da Silva, Chiara Tentori, Carlo Alberto Tondini, Joseph M Grimes, Samuel D Saibil

J Immunother Cancer· January 2021

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Biologic subtypes of melanoma predict survival benefit of combination anti-PD1+anti-CTLA4 immune checkpoint inhibitors versus anti-PD1 monotherapy.
April A N Rose, Susan M Armstrong, David Hogg, Marcus O Butler, Samuel D Saibil

J Immunother Cancer· January 2021

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Immune checkpoint inhibitors in cancer immunotherapy.
Megan E Himmel, Samuel D Saibil, Alexandra P Saltman

CMAJ· June 2020

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IL6 Induces an IL22 CD8 T-cell Subset with Potent Antitumor Function.
Michael St Paul, Samuel D Saibil, Scott C Lien, SeongJun Han, Azin Sayad

Cancer Immunol Res· March 2020

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