Publications by authors named "Samuel Flashner"

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Protocol for single-cell dissociation of head and neck cancer organoids.
Matthew Spence, Isabel Cioffi, Yasuto Tomita, Samuel Flashner, Cecilia Martin

STAR Protoc· September 2025

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Mitochondrial dysfunction drives basal cell hyperplasia in eosinophilic oesophagitis.
Masaki Morimoto, Kento Kawasaki, Niamh McNamee, Samuel Flashner, Rieko Shimonosono

Gut· September 2025

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Aldh2 and the tumor suppressor Trp53 play important roles in alcohol-induced squamous field cancerization.
Yuki Kondo, Shinya Ohashi, Chikatoshi Katada, Yukie Nakai, Yoshihiro Yamamoto, Samuel Flashner

J Gastroenterol· May 2025

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LIN28B-mediated PI3K/AKT pathway activation promotes metastasis in colorectal cancer models.
Alice E Shin, Kensuke Sugiura, Secunda W Kariuki, David A Cohen, Samuel P Flashner

J Clin Invest· April 2025

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Emerging Roles for Transcription Factors During Mitosis.
Samuel Flashner, Jane Azizkhan-Clifford

Cells· February 2025

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Clinical and Biological Perspectives on Noncanonical Esophageal Squamous Cell Carcinoma in Rare Subtypes.
Sydney F Pomenti, Samuel P Flashner, Armando Del Portillo, Hiroshi Nakagawa, Joel Gabre

Am J Gastroenterol· December 2024

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Modeling Epithelial Homeostasis and Perturbation in Three-Dimensional Human Esophageal Organoids.
Masataka Shimonosono, Masaki Morimoto, Wataru Hirose, Yasuto Tomita, Norihiro Matsuura, Samuel Flashner

Biomolecules· September 2024

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Lactate Suppresses Growth of Esophageal Adenocarcinoma Patient-Derived Organoids through Alterations in Tumor NADH/NAD+ Redox State.
Steven H Su, Yosuke Mitani, Tianxia Li, Uma Sachdeva, Samuel Flashner

Biomolecules· September 2024

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Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch.
Kristjan H Gretarsson, Stephen Abini-Agbomson, Susan L Gloor, Daniel N Weinberg, Jamie L McCuiston, Samuel Flashner

Sci Adv· August 2024

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Epithelial overexpression of IL-33 induces eosinophilic esophagitis dependent on IL-13.
Mia Y Masuda, Grace C Pyon, Huijun Luo, William E LeSuer, Arina Putikova, Samuel Flashner

J Allergy Clin Immunol· May 2024

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Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids.
Masataka Shimonosono, Masaki Morimoto, Wataru Hirose, Yasuto Tomita, Norihiro Matsuura, Samuel Flashner

bioRxiv· May 2024

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Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch.
Kristjan H Gretarsson, Stephen Abini-Agbomson, Susan L Gloor, Daniel N Weinberg, Jamie L McCuiston, Samuel Flashner

bioRxiv· March 2024

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ALDH2 dysfunction and alcohol cooperate in cancer stem cell enrichment.
Samuel Flashner, Masataka Shimonosono, Yasuto Tomita, Norihiro Matsuura, Shinya Ohashi

Carcinogenesis· February 2024

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Experimental Modeling of Host-Bacterial Interactions in Head and Neck Squamous Cell Carcinoma.
Ogoegbunam Okolo, Emily Honzel, William R Britton, Victoria X Yu, Samuel Flashner

Cancers (Basel)· December 2023

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Protocol for tumor dissociation and fluorescence-activated cell sorting of human head and neck cancers.
Ogoegbunam Okolo, Victoria Yu, Samuel Flashner, Cecilia Martin, Hiroshi Nakagawa

STAR Protoc· May 2023

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Patient-derived three-dimensional culture techniques model tumor heterogeneity in head and neck cancer.
Anuraag S Parikh, Victoria X Yu, Samuel Flashner, Ogoegbunam B Okolo, Chao Lu

Oral Oncol· March 2023

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Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus.
Alfred D Doyle, Mia Y Masuda, Grace C Pyon, Huijun Luo, Arina Putikova, Samuel Flashner

Allergy· January 2023

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Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids.
Samuel Flashner, Cecilia Martin, Norihiro Matsuura, Masataka Shimonosono, Yasuto Tomita

J Vis Exp· December 2022

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Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation.
Bartosz Mucha, Shuo Qie, Sagar Bajpai, Vincenzo Tarallo, J Nathaniel Diehl, Samuel Flashner

Nat Commun· November 2022

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Transcription factor Sp1 regulates mitotic chromosome assembly and segregation.
Samuel Flashner, Michelle Swift, Aislinn Sowash, Alexander N Fahmy, Jane Azizkhan-Clifford

Chromosoma· September 2022

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Alcohol Metabolism Enriches Squamous Cell Carcinoma Cancer Stem Cells That Survive Oxidative Stress via Autophagy.
Masataka Shimonosono, Koji Tanaka, Samuel Flashner, Satoshi Takada, Norihiro Matsuura

Biomolecules· October 2021

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3D Organoids: An Untapped Platform for Studying Host-Microbiome Interactions in Esophageal Cancers.
Samuel Flashner, Kelley S Yan, Hiroshi Nakagawa

Microorganisms· October 2021

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Understanding the cellular origin and progression of esophageal cancer using esophageal organoids.
Uma M Sachdeva, Masataka Shimonosono, Samuel Flashner, Ricardo Cruz-Acuña, Joel T Gabre

Cancer Lett· July 2021

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DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1.
Michelle L Swift, Kate Beishline, Samuel Flashner, Jane Azizkhan-Clifford

Cell Rep· March 2021

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Caspase cleavage of transcription factor Sp1 enhances apoptosis.
Behzad Torabi, Samuel Flashner, Kate Beishline, Aislinn Sowash, Kelly Donovan

Apoptosis· January 2018

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