Publications by authors named "Samuel Handelman"

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Association of clonal hematopoiesis and mosaic chromosomal alterations with solid malignancy incidence and mortality.
Pinkal Desai, Ying Zhou, Justin Grenet, Samuel K Handelman, Cynthia M Crispino

Cancer· November 2024

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Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution.
Nooriel E Banayan, Blaine J Loughlin, Shikha Singh, Farhad Forouhar, Guanqi Lu, Samuel K Handelman

Protein Sci· March 2024

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Polygenic Risk Prediction in Diverticulitis.
Ana C De Roo, Yanhua Chen, Xiaomeng Du, Samuel Handelman, Mary Byrnes

Ann Surg· June 2023

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Author Correction: Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.
Vincent L Chen, Xiaomeng Du, Yanhua Chen, Annapurna Kuppa, Samuel K Handelman

Nat Commun· June 2023

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Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.
Rishel B Vohnoutka, Annapurna Kuppa, Yash Hegde, Yue Chen, Asmita Pant, Samuel K Handelman

J Mol Endocrinol· April 2023

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A new framework for host-pathogen interaction research.
Hong Yu, Li Li, Anthony Huffman, John Beverley, Junguk Hur, Samuel K Handelman

Front Immunol· January 2023

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Investigating SH-SY5Y Neuroblastoma Cell Surfaceome as a Model for Neuronal-Targeted Novel Therapeutic Modalities.
Pooja Gangras, Valentina Gelfanova, Graham D Williams, Samuel K Handelman, Ryan M Smith

Int J Mol Sci· December 2022

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Population-based meta-analysis and gene-set enrichment identifies FXR/RXR pathway as common to fatty liver disease and serum lipids.
Samuel K Handelman, Yindra M Puentes, Annapurna Kuppa, Yanhua Chen, Xiaomeng Du

Hepatol Commun· November 2022

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BET Bromodomain Inhibition Blocks an AR-Repressed, E2F1-Activated Treatment-Emergent Neuroendocrine Prostate Cancer Lineage Plasticity Program.
Dae-Hwan Kim, Duanchen Sun, William K Storck, Katherine Welker Leng, Chelsea Jenkins, Samuel K Handelman

Clin Cancer Res· September 2021

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Single-Nucleotide Polymorphisms in CD36 are Associated With Macular Pigment Among Children.
Garry J Handelman, Samuel K Handelman

J Nutr· September 2021

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Morphological cell profiling of SARS-CoV-2 infection identifies drug repurposing candidates for COVID-19.
Carmen Mirabelli, Jesse W Wotring, Charles J Zhang, Sean M McCarty, Reid Fursmidt, Samuel K Handelman

Proc Natl Acad Sci U S A· September 2021

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Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis.
Matthew T Patrick, Philip E Stuart, Haihan Zhang, Qingyuan Zhao, Xianyong Yin, Samuel K Handelman

J Invest Dermatol· June 2021

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Standing Variations Modeling Captures Inter-Individual Heterogeneity in a Deterministic Model of Prostate Cancer Response to Combination Therapy.
Harsh Vardhan Jain, Inmaculada C Sorribes, Samuel K Handelman, Johnna Barnaby, Trachette L Jackson

Cancers (Basel)· April 2021

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A Meta-Analysis of the Transferability of Bone Mineral Density Genetic Loci Associations From European to African Ancestry Populations.
Michelle S Yau, Allison L Kuipers, Ryan Price, Aude Nicolas, Salman M Tajuddin, Samuel K Handelman

J Bone Miner Res· March 2021

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Loci identified by a genome-wide association study of carotid artery stenosis in the eMERGE network.
Melody R Palmer, Daniel S Kim, David R Crosslin, Ian B Stanaway, Elisabeth A Rosenthal, Samuel K Handelman

Genet Epidemiol· February 2021

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Genome-wide association study of serum liver enzymes implicates diverse metabolic and liver pathology.
Vincent L Chen, Xiaomeng Du, Yanhua Chen, Annapurna Kuppa, Samuel K Handelman

Nat Commun· February 2021

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A Noncoding Variant Near PPP1R3B Promotes Liver Glycogen Storage and MetS, but Protects Against Myocardial Infarction.
Bratati Kahali, Yue Chen, Mary F Feitosa, Lawrence F Bielak, Jeffrey R O'Connell, Samuel K Handelman

J Clin Endocrinol Metab· January 2021

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Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection.
Yingtong Liu, Junguk Hur, Wallace K B Chan, Zhigang Wang, Jiangan Xie, Samuel Handelman

Sci Data· January 2021

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Morphological Cell Profiling of SARS-CoV-2 Infection Identifies Drug Repurposing Candidates for COVID-19.
Carmen Mirabelli, Jesse W Wotring, Charles J Zhang, Sean M McCarty, Reid Fursmidt, Samuel K Handelman

bioRxiv· December 2020

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Mitochondrial GWAS and association of nuclear - mitochondrial epistasis with BMI in T1DM patients.
Agnieszka H Ludwig-Słomczyńska, Michał T Seweryn, Przemysław Kapusta, Ewelina Pitera, Samuel K Handelman

BMC Med Genomics· July 2020

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The plasma metabolome of women in early pregnancy differs from that of non-pregnant women.
Samuel K Handelman, Roberto Romero, Adi L Tarca, Percy Pacora, Brian Ingram

PLoS One· March 2020

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Genetic variants that associate with cirrhosis have pleiotropic effects on human traits.
Vincent L Chen, Yanhua Chen, Xiaomeng Du, Samuel K Handelman, Elizabeth K Speliotes

Liver Int· February 2020

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Mitigating temozolomide resistance in glioblastoma via DNA damage-repair inhibition.
Inmaculada C Sorribes, Samuel K Handelman, Harsh V Jain

J R Soc Interface· January 2020

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The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts.
Rishel B Vohnoutka, Anushree C Gulvady, Gregory Goreczny, Kyle Alpha, Samuel K Handelman

Mol Biol Cell· December 2019

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Identifying Interaction Clusters for MiRNA and MRNA Pairs in TCGA Network.
Xinqing Dai, Lizhong Ding, Hannah Liu, Zesheng Xu, Hui Jiang, Samuel K Handelman

Genes (Basel)· September 2019

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