Publications by authors named "Samuel Lawn"

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Design and Evaluation of ZD06519, a Novel Camptothecin Payload for Antibody Drug Conjugates.
Mark E Petersen, Michael G Brant, Manuel Lasalle, Samir Das, Renee Duan, Samuel O Lawn

Mol Cancer Ther· May 2024

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Generation and structure-activity relationships of novel imidazo-thienopyridine based TLR7 agonists: application as payloads for immunostimulatory antibody drug-conjugates.
Michael G Brant, Graham A E Garnett, Joy Guedia, Manuel Lasalle, Samuel Lawn

Bioorg Med Chem Lett· July 2023

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Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors.
Shiekh Tanveer Ahmad, Alexandra D Rogers, Myra J Chen, Rajiv Dixit, Lata Adnani, Samuel O Lawn

Nat Commun· May 2019

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Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells.
Samuel Lawn, Niveditha Krishna, Alexandra Pisklakova, Xiaotao Qu, David A Fenstermacher

J Biol Chem· February 2015

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p75 neurotrophin receptor cleavage by α- and γ-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells.
Peter A Forsyth, Niveditha Krishna, Samuel Lawn, J Gerardo Valadez, Xiaotao Qu

J Biol Chem· March 2014

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RAS/ERK signaling controls proneural genetic programs in cortical development and gliomagenesis.
Saiqun Li, Pierre Mattar, Rajiv Dixit, Samuel O Lawn, Grey Wilkinson

J Neurosci· February 2014

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P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments.
Andrew D Campbell, Samuel Lawn, Lynn C McGarry, Heidi C Welch, Bradford W Ozanne

PLoS One· September 2013

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P-Rex1 is required for efficient melanoblast migration and melanoma metastasis.
Colin R Lindsay, Samuel Lawn, Andrew D Campbell, William J Faller, Florian Rambow

Nat Commun· November 2011

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