Publications by authors named "Samuel LoPresti"

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Effect of Fibroblast Signaling on Macrophage Polarization.
Samuel T LoPresti, Mangesh M Kulkarni, Dana R Julian, Zariel I Johnson, Brandon L Lantonio

Am J Pathol· July 2025

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Enhanced epigenetic modulation via mRNA-encapsulated lipid nanoparticles enables targeted anti-inflammatory control.
Tahere Mokhtari, Mohammad N Taheri, Sarah Akhlaghi, Armin Aryannejad, Yuda Xiang, Samuel LoPresti

bioRxiv· February 2025

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Maternal milk cell components are uptaken by infant liver macrophages via extracellular vesicle mediated transport.
Rose Doerfler, Saigopalakrishna Yerneni, Samuel LoPresti, Namit Chaudhary, Alexandra Newby

FASEB J· January 2025

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Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d.
Namit Chaudhary, Lisa N Kasiewicz, Alexandra N Newby, Mariah L Arral, Saigopalakrishna S Yerneni, Samuel T LoPresti

Nat Biomed Eng· November 2024

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Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes.
Namit Chaudhary, Alexandra N Newby, Mariah L Arral, Saigopalakrishna S Yerneni, Samuel T LoPresti

Proc Natl Acad Sci U S A· March 2024

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Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer.
Jilian R Melamed, Saigopalakrishna S Yerneni, Mariah L Arral, Samuel T LoPresti, Namit Chaudhary

Sci Adv· January 2023

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Inductive Remodeling of Extracellular Matrix Scaffolds in the Temporomandibular Joint of Pigs.
Bryan N Brown, William L Chung, Jesse Lowe, Samuel T LoPresti, Jonathan Cheetham

Tissue Eng Part A· May 2022

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The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs.
Samuel T LoPresti, Mariah L Arral, Namit Chaudhary, Kathryn A Whitehead

J Control Release· May 2022

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Macrophage phenotype and function are dependent upon the composition and biomechanics of the local cardiac tissue microenvironment.
Martin Haschak, Samuel LoPresti, Elizabeth Stahl, Siddhartha Dash, Branimir Popovich

Aging (Albany NY)· May 2021

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Distinct macrophage populations and phenotypes associated with IL-4 mediated immunomodulation at the host implant interface.
Daniel Hachim, Samuel T LoPresti, Rahul D Rege, Yuta Umeda, Aimon Iftikhar

Biomater Sci· October 2020

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Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2.
Elizabeth C Stahl, Evan R Delgado, Frances Alencastro, Samuel T LoPresti, Patrick D Wilkinson

Am J Pathol· February 2020

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Distinct release strategies are required to modulate macrophage phenotype in young versus aged animals.
Daniel Hachim, Aimon Iftikhar, Samuel T LoPresti, Alexis L Nolfi, Shweta Ravichandar

J Control Release· July 2019

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Injectable, porous, biohybrid hydrogels incorporating decellularized tissue components for soft tissue applications.
Yang Zhu, Sato Hideyoshi, Hongbin Jiang, Yasumoto Matsumura, Jenna L Dziki, Samuel T LoPresti

Acta Biomater· June 2018

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Effect of Source Animal Age upon Macrophage Response to Extracellular Matrix Biomaterials.
Samuel T LoPresti, Bryan N Brown

J Immunol Regen Med· March 2018

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Nerve-specific, xenogeneic extracellular matrix hydrogel promotes recovery following peripheral nerve injury.
Travis A Prest, Eric Yeager, Samuel T LoPresti, Emilija Zygelyte, Matthew J Martin

J Biomed Mater Res A· February 2018

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Matrix-Bound Nanovesicles Recapitulate Extracellular Matrix Effects on Macrophage Phenotype.
Luai Huleihel, Joseph G Bartolacci, Jenna L Dziki, Tatiana Vorobyov, Brooke Arnold, Samuel T LoPresti

Tissue Eng Part A· November 2017

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Effects of aging upon the host response to implants.
Daniel Hachim, Na Wang, Samuel T Lopresti, Elizabeth C Stahl, Yuta U Umeda

J Biomed Mater Res A· May 2017

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Effects of age-related shifts in cellular function and local microenvironment upon the innate immune response to implants.
Bryan N Brown, Martin J Haschak, Samuel T Lopresti, Elizabeth C Stahl

Semin Immunol· February 2017

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Macrophage phenotype in response to ECM bioscaffolds.
Luai Huleihel, Jenna L Dziki, Joseph G Bartolacci, Theresa Rausch, Michelle E Scarritt, Samuel T LoPresti

Semin Immunol· February 2017

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Shifts in macrophage phenotype at the biomaterial interface via IL-4 eluting coatings are associated with improved implant integration.
Daniel Hachim, Samuel T LoPresti, Cecelia C Yates, Bryan N Brown

Biomaterials· January 2017

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Macrophage polarization in response to ECM coated polypropylene mesh.
Matthew T Wolf, Christopher L Dearth, Christian A Ranallo, Samuel T LoPresti, Lisa E Carey

Biomaterials· August 2014

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