Publications by authors named "Samuel Lockwood"

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Accelerated onset of chronic wasting disease in elk (Cervus canadensis) vaccinated with a PrP-specific vaccine and housed in a prion contaminated environment.
Mary E Wood, Philip Griebel, Matthew L Huizenga, Samuel Lockwood, Cole Hansen

Vaccine· November 2018

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Novel astaxanthin prodrug (CDX-085) attenuates thrombosis in a mouse model.
Sanjoy K Khan, Tadeusz Malinski, R Preston Mason, Ruslan Kubant, Robert F Jacob, Samuel F Lockwood

Thromb Res· October 2010

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Electron- and energy-transfer properties of hydrophilic carotenoids.
Hans-Richard Sliwka, Thor-Bernt Melø, Bente Jeanette Foss, Shams H Abdel-Hafez, Vassilia Partali, Samuel F Lockwood

Chemistry· August 2007

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Hydrophilic carotenoids: surface properties and aggregation of an astaxanthin-lysine conjugate, a rigid, long-chain, highly unsaturated and highly water-soluble tetracationic bolaamphiphile.
Stine Nalum Naess, Hans-Richard Sliwka, Vassilia Partali, Thor Bernt Melø, K Razi Naqvi, Samuel F Lockwood

Chem Phys Lipids· August 2007

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Differential effects of carotenoids on lipid peroxidation due to membrane interactions: X-ray diffraction analysis.
Hyesun P McNulty, Jungsoo Byun, Samuel F Lockwood, Robert F Jacob, R Preston Mason

Biochim Biophys Acta· January 2007

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Rofecoxib increases susceptibility of human LDL and membrane lipids to oxidative damage: a mechanism of cardiotoxicity.
R Preston Mason, Mary F Walter, Hyesun P McNulty, Samuel F Lockwood, Jungsoo Byun

J Cardiovasc Pharmacol· November 2006

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Molecular modeling of the non-covalent binding of the dietary tomato carotenoids lycopene and lycophyll, and selected oxidative metabolites with 5-lipoxygenase.
Eszter Hazai, Zsolt Bikádi, Ferenc Zsila, Samuel F Lockwood

Bioorg Med Chem· October 2006

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Retrometabolic syntheses of astaxanthin (3,3'-dihydroxy-beta,beta-carotene-4,4'-dione) conjugates: a novel approach to oral and parenteral cardio-protection.
Samuel F Lockwood, Henry L Jackson, Garrett J Gross

Cardiovasc Hematol Agents Med Chem· October 2006

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Hydrophilic carotenoid amphiphiles: methods of synthesis and biological applications.
Bente Jeanette Foss, Geoff Nadolski, Samuel F Lockwood

Mini Rev Med Chem· September 2006

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Molecular modeling of non-covalent binding of homochiral (3S,3'S)-astaxanthin to matrix metalloproteinase-13 (MMP-13).
Zsolt Bikádi, Eszter Hazai, Ferenc Zsila, Samuel F Lockwood

Bioorg Med Chem· August 2006

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Association studies of aggregated aqueous lutein diphosphate with human serum albumin and alpha1-acid glycoprotein in vitro: evidence from circular dichroism and electronic absorption spectroscopy.
Ferenc Zsila, Geoff Nadolski, Samuel F Lockwood

Bioorg Med Chem Lett· July 2006

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The effects of oral Cardax (disodium disuccinate astaxanthin) on multiple independent oxidative stress markers in a mouse peritoneal inflammation model: influence on 5-lipoxygenase in vitro and in vivo.
Samuel F Lockwood, Marc S Penn, Stanley L Hazen, Zsolt Bikádi, Ferenc Zsila

Life Sci· June 2006

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Disodium disuccinate astaxanthin (Cardax): antioxidant and antiinflammatory cardioprotection.
Samuel F Lockwood, Garrett J Gross

Cardiovasc Drug Rev· May 2006

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Purification of synthetic all-E lycophyll (psi,psi-carotene-16,16'-diol).
Cristi L Braun, Henry L Jackson, Samuel F Lockwood, Geoff Nadolski

J Chromatogr B Analyt Technol Biomed Life Sci· April 2006

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The synthesis and aqueous superoxide anion scavenging of water-dispersible lutein esters.
Geoff Nadolski, Arturo J Cardounel, Jay L Zweier, Samuel F Lockwood

Bioorg Med Chem Lett· February 2006

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Seven day oral supplementation with Cardax (disodium disuccinate astaxanthin) provides significant cardioprotection and reduces oxidative stress in rats.
Garrett J Gross, Stanley L Hazen, Samuel F Lockwood

Mol Cell Biochem· February 2006

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Inhibition of chemically-induced neoplastic transformation by a novel tetrasodium diphosphate astaxanthin derivative.
Laura M Hix, Dean A Frey, Mark D McLaws, Marianne Østerlie, Samuel F Lockwood

Carcinogenesis· September 2005

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Disodium Disuccinate Astaxanthin (Cardax) attenuates complement activation and reduces myocardial injury following ischemia/reperfusion.
D Adam Lauver, Samuel F Lockwood, Benedict R Lucchesi

J Pharmacol Exp Ther· August 2005

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In vitro binding of leukotriene B4 (LTB4) to human serum albumin: evidence from spectroscopic, molecular modeling, and competitive displacement studies.
Ferenc Zsila, Zsolt Bikádi, Samuel F Lockwood

Bioorg Med Chem Lett· August 2005

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Circular dichroism and absorption spectroscopic data reveal binding of the natural cis-carotenoid bixin to human alpha1-acid glycoprotein.
Ferenc Zsila, Péter Molnár, József Deli, Samuel F Lockwood

Bioorg Chem· August 2005

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Hydrophilic carotenoids: surface properties and aqueous aggregation of a rigid, long-chain, highly unsaturated dianionic bolaamphiphile with a carotenoid spacer.
Bente Jeanette Foss, Hans-Richard Sliwka, Vassilia Partali, Stine Nalum Naess, Arnljot Elgsaeter, Samuel F Lockwood

Chem Phys Lipids· June 2005

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Acute and chronic administration of disodium disuccinate astaxanthin (Cardax) produces marked cardioprotection in dog hearts.
Garrett J Gross, Samuel F Lockwood

Mol Cell Biochem· April 2005

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Bioactive carotenoids: potent antioxidants and regulators of gene expression.
Laura M Hix, Samuel F Lockwood, John S Bertram

Redox Rep· March 2005

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In vitro plasma protein binding and aqueous aggregation behavior of astaxanthin dilysinate tetrahydrochloride.
Ferenc Zsila, Ilona Fitos, Zsolt Bikádi, Miklós Simonyi, Henry L Jackson, Samuel F Lockwood

Bioorg Med Chem Lett· November 2004

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Synthesis, characterization, and direct aqueous superoxide anion scavenging of a highly water-dispersible astaxanthin-amino acid conjugate.
Henry L Jackson, Arturo J Cardounel, Jay L Zweier, Samuel F Lockwood

Bioorg Med Chem Lett· August 2004

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