Publications by authors named "Samuel Mantey"

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Gastrin-Releasing Peptide Receptors Stimulate MAPK-Mediated Growth of Lung Cancer Cells by Transactivating HER4 in a Neuregulin-1, MAP Kinase-Dependent Manner Requiring Activation of the ROS-System.
Terry W Moody, Irene Ramos-Alvarez, Tatiana Iordanskaia, Samuel A Mantey, Robert T Jensen

Biology (Basel)· September 2025

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Bombesin Receptor Subtype-3 Regulates Tumor Growth by HER2 Tyrosine Phosphorylation in a Reactive Oxygen Species-Dependent Manner in Lung Cancer Cells.
Terry W Moody, Irene Ramos-Alvarez, Samuel A Mantey, Robert T Jensen

Targets (Basel)· March 2025

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The Nonpeptide Agonist MK-5046 Functions As an Allosteric Agonist for the Bombesin Receptor Subtype-3.
Irene Ramos-Alvarez, Tatiana Iordanskaia, Samuel A Mantey, Robert T Jensen

J Pharmacol Exp Ther· August 2022

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Bombesin Receptor Family Activation and CNS/Neural Tumors: Review of Evidence Supporting Possible Role for Novel Targeted Therapy.
Terry W Moody, Lingaku Lee, Irene Ramos-Alvarez, Tatiana Iordanskaia, Samuel A Mantey

Front Endocrinol (Lausanne)· February 2022

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Neuropeptide bombesin receptor activation stimulates growth of lung cancer cells through HER3 with a MAPK-dependent mechanism.
Lingaku Lee, Irene Ramos-Alvarez, Terry W Moody, Samuel A Mantey, Robert T Jensen

Biochim Biophys Acta Mol Cell Res· April 2020

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Development and Characterization of a Novel, High-Affinity, Specific, Radiolabeled Ligand for BRS-3 Receptors.
Irene Ramos-Alvarez, Lingaku Lee, Samuel A Mantey, Robert T Jensen

J Pharmacol Exp Ther· June 2019

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Activation of bombesin receptor Subtype-3 by [D-Tyr,β-Ala,Phe,Nle]bombesin increased glucose uptake and lipogenesis in human and rat adipocytes.
Zaida Moreno-Villegas, Antonio Martín-Duce, César Aparicio, Sergio Portal-Núñez, Raúl Sanz, Samuel A Mantey

Mol Cell Endocrinol· October 2018

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A possible new target in lung-cancer cells: The orphan receptor, bombesin receptor subtype-3.
Paola Moreno, Samuel A Mantey, Suk H Lee, Irene Ramos-Álvarez, Terry W Moody

Peptides· March 2018

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AM-37 and ST-36 Are Small Molecule Bombesin Receptor Antagonists.
Terry W Moody, Nicole Tashakkori, Samuel A Mantey, Paola Moreno, Irene Ramos-Alvarez

Front Endocrinol (Lausanne)· July 2017

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Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells.
Terry W Moody, Irene Ramos-Alvarez, Paula Moreno, Samuel A Mantey, Lisa Ridnour

Peptides· April 2017

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Molecular basis for high affinity and selectivity of peptide antagonist, Bantag-1, for the orphan BB3 receptor.
Taichi Nakamura, Irene Ramos-Álvarez, Tatiana Iordanskaia, Paola Moreno, Samuel A Mantey

Biochem Pharmacol· September 2016

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Novel chiral-diazepines function as specific, selective receptor agonists with variable coupling and species variability in human, mouse and rat BRS-3 receptor cells.
Irene Ramos-Álvarez, Taichi Nakamura, Samuel A Mantey, Paola Moreno, Bernardo Nuche-Berenguer

Peptides· January 2016

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Insights into bombesin receptors and ligands: Highlighting recent advances.
Irene Ramos-Álvarez, Paola Moreno, Samuel A Mantey, Taichi Nakamura, Bernardo Nuche-Berenguer

Peptides· October 2015

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A structure-function study of PACAP using conformationally restricted analogs: Identification of PAC1 receptor-selective PACAP agonists.
Irene Ramos-Álvarez, Samuel A Mantey, Taichi Nakamura, Bernardo Nuche-Berenguer, Paola Moreno

Peptides· April 2015

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ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth.
Terry W Moody, Samuel A Mantey, Paola Moreno, Taichi Nakamura, Enza Lacivita

Peptides· February 2015

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SR48692 inhibits non-small cell lung cancer proliferation in an EGF receptor-dependent manner.
Terry W Moody, Daniel C Chan, Samuel A Mantey, Paola Moreno, Robert T Jensen

Life Sci· March 2014

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Comparative pharmacology of bombesin receptor subtype-3, nonpeptide agonist MK-5046, a universal peptide agonist, and peptide antagonist Bantag-1 for human bombesin receptors.
Paola Moreno, Samuel A Mantey, Bernardo Nuche-Berenguer, Marc L Reitman, Nieves González

J Pharmacol Exp Ther· October 2013

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Bombesin receptor subtype-3 (BRS-3), a novel candidate as therapeutic molecular target in obesity and diabetes.
Irene Ramos-Álvarez, Antonio Martín-Duce, Zaida Moreno-Villegas, Raúl Sanz, César Aparicio, Samuel A Mantey

Mol Cell Endocrinol· March 2013

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The molecular basis for high affinity of a universal ligand for human bombesin receptor (BnR) family members.
Hirotsugu Uehara, Simon J Hocart, Nieves González, Samuel A Mantey, Tomoo Nakagawa

Biochem Pharmacol· October 2012

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Bombesin receptor subtype-3 agonists stimulate the growth of lung cancer cells and increase EGF receptor tyrosine phosphorylation.
Terry W Moody, Veronica Sancho, Alessia di Florio, Bernardo Nuche-Berenguer, Samuel Mantey

Peptides· August 2011

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Pharmacology and selectivity of various natural and synthetic bombesin related peptide agonists for human and rat bombesin receptors differs.
Hirotsugu Uehara, Nieves González, Veronica Sancho, Samuel A Mantey, Bernardo Nuche-Berenguer

Peptides· August 2011

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Effect of brain- and tumor-derived connective tissue growth factor on glioma invasion.
Lincoln A Edwards, Kevin Woolard, Myung Jin Son, Aiguo Li, Jeongwu Lee, Samuel A Mantey

J Natl Cancer Inst· August 2011

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Pharmacology of putative selective hBRS-3 receptor agonists for human bombesin receptors (BnR): affinities, potencies and selectivity in multiple native and BnR transfected cells.
Veronica Sancho, Terry W Moody, Samuel A Mantey, Alessia Di Florio, Hirotsugu Uehara

Peptides· August 2010

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Neuromedin B receptors regulate EGF receptor tyrosine phosphorylation in lung cancer cells.
Terry W Moody, Marc J Berna, Samuel Mantey, Veronica Sancho, Lisa Ridnour

Eur J Pharmacol· July 2010

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Molecular basis for the selectivity of the mammalian bombesin peptide, neuromedin B, for its receptor.
Nieves González, Tomoo Nakagawa, Samuel A Mantey, Veronica Sancho, Hirotsugu Uehara

J Pharmacol Exp Ther· October 2009

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