Publications by authors named "Samuel Singleton"

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Stress, epigenetic remodeling and FKBP51: Pathways to chronic pain vulnerability.
Oakley B Morgan, Samuel Singleton, Roxana Florea, Sara Hestehave, Tim Sarter

Brain Behav Immun· November 2025

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Analgesia through FKBP51 inhibition at disease onset confers lasting relief from sensory and emotional chronic pain symptoms.
Sara Hestehave, Roxana Florea, Samuel Singleton, Alex J H Fedorec, Sara Caxaria

Proc Natl Acad Sci U S A· November 2025

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Activation of μ receptors by SR-17018 through a distinctive mechanism.
Samuel Singleton, Clara Dieterle, David J Walker, Tyko Runeberg, Andrew S Oswald

Neuropharmacology· November 2024

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Morphine-induced mechanical hypersensitivity in mice requires δ receptors, β-arrestin2, and c-Src activity.
Samuel Singleton, Tim G Hales

J Physiol· April 2023

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TRV130 partial agonism and capacity to induce anti-nociceptive tolerance revealed through reducing available μ-opioid receptor number.
Samuel Singleton, Daniel T Baptista-Hon, Emily Edelsten, Kirsty S McCaughey, Ewan Camplisson

Br J Pharmacol· April 2021

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Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives.
Daniel T Baptista-Hon, Mark Smith, Samuel Singleton, Lysbeth H Antonides, Niamh Nic Daeid

Br J Pharmacol· August 2020

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