Publications by authors named "Sandra Abramowicz"

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IL-18 inhibition enlarges lesions, necrotic cores and thickens fibrous caps in clonal hematopoiesis-driven atherosclerosis.
Mojdeh Tavallaie, Cheng-Chieh Hsu, Brian D Hardaway, Huijuan Dou, Trevor Fidler, Sandra E Abramowicz

bioRxiv· June 2025

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Cholesterol trafficking to the ER leads to the activation of CaMKII/JNK/NLRP3 and promotes atherosclerosis.
Mustafa Yalcinkaya, Wenli Liu, Tong Xiao, Sandra Abramowicz, Ranran Wang

J Lipid Res· April 2024

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Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis.
Trevor P Fidler, Andrew Dunbar, Eunyoung Kim, Brian Hardaway, Jessica Pauli, Sandra Abramowicz

Nat Cardiovasc Res· January 2024

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BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis in Clonal Hematopoiesis.
Mustafa Yalcinkaya, Wenli Liu, Leigh-Anne Thomas, Malgorzata Olszewska, Tong Xiao, Sandra Abramowicz

Circulation· November 2023

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Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion.
Mustafa Yalcinkaya, Panagiotis Fotakis, Wenli Liu, Kaori Endo-Umeda, Huijuan Dou, Sandra Abramowicz

Cardiovasc Res· May 2023

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Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis.
Wenli Liu, Nataliya Östberg, Mustafa Yalcinkaya, Huijuan Dou, Kaori Endo-Umeda, Sandra Abramowicz

J Clin Invest· July 2022

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Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis.
Kaori Endo-Umeda, Eunyoung Kim, David G Thomas, Wenli Liu, Huijuan Dou, Sandra Abramowicz

Arterioscler Thromb Vasc Biol· June 2022

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Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency.
Huijuan Dou, Andriana Kotini, Wenli Liu, Trevor Fidler, Kaori Endo-Umeda, Sandra Abramowicz

Circulation· December 2021

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The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.
Trevor P Fidler, Chenyi Xue, Mustafa Yalcinkaya, Brian Hardaway, Sandra Abramowicz

Nature· April 2021

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Anti-Inflammatory Effects of HDL (High-Density Lipoprotein) in Macrophages Predominate Over Proinflammatory Effects in Atherosclerotic Plaques.
Panagiotis Fotakis, Vishal Kothari, David G Thomas, Marit Westerterp, Matthew M Molusky, Sandra Abramowicz

Arterioscler Thromb Vasc Biol· December 2019

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Cholesterol Efflux Pathways Suppress Inflammasome Activation, NETosis, and Atherogenesis.
Marit Westerterp, Panagiotis Fotakis, Mireille Ouimet, Andrea E Bochem, Hanrui Zhang, Sandra Abramowicz

Circulation· August 2018

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Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.
Marit Westerterp, Kyoichiro Tsuchiya, Ian W Tattersall, Panagiotis Fotakis, Andrea E Bochem, Sandra Abramowicz

Arterioscler Thromb Vasc Biol· July 2016

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TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
Joanne Hsieh, Masahiro Koseki, Matthew M Molusky, Emi Yakushiji, Ikuyo Ichi, Sandra Abramowicz

Nature· July 2016

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Enhanced Megakaryopoiesis and Platelet Activity in Hypercholesterolemic, B6-Ldlr-/-, Cdkn2a-Deficient Mice.
Wei Wang, Seon Oh, Mark Koester, Sandra Abramowicz, Nan Wang

Circ Cardiovasc Genet· June 2016

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Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency.
Mi Wang, Manikandan Subramanian, Sandra Abramowicz, Andrew J Murphy, Ayelet Gonen

Arterioscler Thromb Vasc Biol· May 2014

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Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.
Ding Ai, Hongfeng Jiang, Marit Westerterp, Andrew J Murphy, Mi Wang, Sandra Abramowicz

Circ Res· May 2014

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Deficiency of ATP-binding cassette transporter B6 in megakaryocyte progenitors accelerates atherosclerosis in mice.
Andrew J Murphy, Vincent Sarrazy, Nan Wang, Nora Bijl, Sandra Abramowicz

Arterioscler Thromb Vasc Biol· April 2014

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Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells.
Mojdeh S Kappus, Andrew J Murphy, Sandra Abramowicz, Vusisizwe Ntonga, Carrie L Welch

Arterioscler Thromb Vasc Biol· February 2014

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Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children.
Sonia Tolani, Tamara A Pagler, Andrew J Murphy, Andrea E Bochem, Sandra Abramowicz

Atherosclerosis· July 2013

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Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Marit Westerterp, Andrew J Murphy, Mi Wang, Tamara A Pagler, Yuliya Vengrenyuk, Sandra Abramowicz

Circ Res· May 2013

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ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.
Andrew J Murphy, Mani Akhtari, Sonia Tolani, Tamara Pagler, Nora Bijl, Sandra Abramowicz

J Clin Invest· October 2011

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