Publications by authors named "Sandra Heil"

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Evaluation of the Performance of Newborn Screening for Tyrosinemia Type 1 in The Netherlands: Suggestions for Improvements Using Additional Biomarkers in Addition to Succinylacetone.
Marelle J Bouva, Allysa M Kuypers, Evelien A Kemper, Rose E Maase, Annet M Bosch, Sandra G Heil

Int J Neonatal Screen· May 2025

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A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation.
Giulietta S Monasso, Thanh T Hoang, Giulia Mancano, Sílvia Fernández-Barrés, John Dou, Sandra G Heil

Epigenetics· December 2023

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Methotrexate Polyglutamates Exposure - Response Modeling in a Large Cohort of Rheumatoid Arthritis Patients Starting Methotrexate.
Renske C F Hebing, Imke H Bartelink, Helen R Gosselt, Sandra G Heil, Mauritis C F J de Rotte

Clin Pharmacol Ther· October 2023

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Pharmacokinetics of oral and subcutaneous methotrexate in red and white blood cells in patients with early rheumatoid arthritis: the methotrexate monitoring trial.
Renske Cf Hebing, Marry Lin, Maja Bulatovic Calasan, Ittai B Muller, Sohaila Mahmoud, Sandra Heil

Ann Rheum Dis· April 2023

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"Macro transcobalamin causing raised vitamin B12: Case-based laboratory investigation".
Sjoerd N Duim, L Tom Vlasveld, Stephanie T P Mezger, Alma M A Mingels, Christian R B Ramakers, Sandra G Heil

Ann Clin Biochem· July 2022

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A Hypomethylating Ketogenic Diet in Apolipoprotein E-Deficient Mice: A Pilot Study on Vascular Effects and Specific Epigenetic Changes.
Rita Castro, Courtney A Whalen, Sean Gullette, Floyd J Mattie, Cristina Florindo, Sandra G Heil

Nutrients· October 2021

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Epigenome wide association study of response to methotrexate in early rheumatoid arthritis patients.
Helen R Gosselt, Costanza L Vallerga, Pooja R Mandaviya, Erik Lubberts, Johanna M W Hazes, Sandra G Heil

PLoS One· September 2021

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Vitamin B12, folate and homocysteine concentrations during pregnancy and early signs of atherosclerosis at school-age.
Giulietta S Monasso, Janine F Felix, Sandra G Heil, Yolanda B de Rijke, Romy Gaillard

Clin Nutr· September 2021

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Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age.
Giulietta S Monasso, Susana Santos, Madelon L Geurtsen, Sandra G Heil, Janine F Felix

J Nutr· June 2021

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Genetic variants associated with methotrexate-induced mucositis in cancer treatment: A systematic review and meta-analysis.
Hedy Maagdenberg, Natanja Oosterom, Jolanda Zanen, Donato Gemmati, Rachael E Windsor, Sandra G Heil

Crit Rev Oncol Hematol· May 2021

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Associations of circulating folate, vitamin B12 and homocysteine concentrations in early pregnancy and cord blood with epigenetic gestational age: the Generation R Study.
Giulietta S Monasso, Leanne K Küpers, Vincent W V Jaddoe, Sandra G Heil, Janine F Felix

Clin Epigenetics· April 2021

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An Atherogenic Diet Disturbs Expression in Liver and Adipocyte Tissues of Apolipoprotein E-Deficient Mice: New Insights into an Old Model of Experimental Atherosclerosis.
Inês V da Silva, Courtney A Whalen, Floyd J Mattie, Cristina Florindo, Neil K Huang, Sandra G Heil

Biomedicines· February 2021

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Global DNA (hydroxy)methylation is stable over time under several storage conditions and temperatures.
Helen R Gosselt, Pieter H Griffioen, Bertrand D van Zelst, Natanja Oosterom, Robert de Jonge, Sandra G Heil

Epigenetics· January 2021

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Validation of a Prognostic Multivariable Prediction Model for Insufficient Clinical Response to Methotrexate in Early Rheumatoid Arthritis and Its Clinical Application in Evidencio.
Helen R Gosselt, Maxime M A Verhoeven, Maurits C F J de Rotte, Saskia M F Pluijm, Ittai B Muller, Sandra G Heil

Rheumatol Ther· December 2020

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Identification of Metabolic Biomarkers in Relation to Methotrexate Response in Early Rheumatoid Arthritis.
Helen R Gosselt, Ittai B Muller, Gerrit Jansen, Michel van Weeghel, Frédéric M Vaz, Sandra G Heil

J Pers Med· December 2020

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No Effect of Diet-Induced Mild Hyperhomocysteinemia on Vascular Methylating Capacity, Atherosclerosis Progression, and Specific Histone Methylation.
Courtney A Whalen, Floyd J Mattie, Cristina Florindo, Bertrand van Zelst, Neil K Huang, Sandra G Heil

Nutrients· July 2020

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Lower S-adenosylmethionine levels and DNA hypomethylation of placental growth factor (PlGF) in placental tissue of early-onset preeclampsia-complicated pregnancies.
Sandra G Heil, Emilie M Herzog, Pieter H Griffioen, Bertrand van Zelst, Sten P Willemsen

PLoS One· April 2020

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Changes in intracellular folate metabolism during high-dose methotrexate and Leucovorin rescue therapy in children with acute lymphoblastic leukemia.
Natanja Oosterom, Robert de Jonge, Desiree E C Smith, Rob Pieters, Wim J E Tissing, Sandra G Heil

PLoS One· March 2020

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Reply to P-A Dugué et al.
Pooja R Mandaviya, Joyce B J van Meurs, Sandra G Heil

Am J Clin Nutr· January 2020

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Multicentre evaluation of the Roche Elecsys® Active B (holotranscobalamin) electro-chemiluminescence immunoassay.
Sandra G Heil, Petra Bodenburg, Peter Findeisen, Silke Luebcke, Yuli Sun

Ann Clin Biochem· November 2019

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Association of dietary folate and vitamin B-12 intake with genome-wide DNA methylation in blood: a large-scale epigenome-wide association analysis in 5841 individuals.
Pooja R Mandaviya, Roby Joehanes, Jennifer Brody, Juan E Castillo-Fernandez, Koen F Dekkers, Sandra G Heil

Am J Clin Nutr· August 2019

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Higher baseline global leukocyte DNA methylation is associated with MTX non-response in early RA patients.
Helen R Gosselt, Bertrand D van Zelst, Maurits C F J de Rotte, Johanna M W Hazes, Robert de Jonge, Sandra G Heil

Arthritis Res Ther· June 2019

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Genetics of high-dose methotrexate-induced oral mucositis: current perspectives.
Sandra G Heil

Pharmacogenomics· June 2019

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Vitamin B12 Intake From Animal Foods, Biomarkers, and Health Aspects.
Rima Obeid, Sandra G Heil, Maxime M A Verhoeven, Ellen G H M van den Heuvel, Lisette C P G M de Groot

Front Nutr· June 2019

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Intakes of Vitamin B-12 from Dairy Food, Meat, and Fish and Shellfish Are Independently and Positively Associated with Vitamin B-12 Biomarker Status in Pregnant Dutch Women.
Karlijn F M Denissen, Sandra G Heil, Simone J P M Eussen, Jim P J Heeskens, Carel Thijs

J Nutr· January 2019

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