Publications by authors named "Sandra Holt"

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Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin.
Sandra Holt, Ben Paylor, Linda Boldrup, Kirsi Alajakku, Séverine Vandevoorde

Eur J Pharmacol· June 2007

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The potency of the fatty acid amide hydrolase inhibitor URB597 is dependent upon the assay pH.
Ben Paylor, Sandra Holt, Christopher J Fowler

Pharmacol Res· December 2006

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The endocannabinoid system: current pharmacological research and therapeutic possibilities.
Kent-Olov Jonsson, Sandra Holt, Christopher J Fowler

Basic Clin Pharmacol Toxicol· February 2006

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Inhibitors of fatty acid amide hydrolase reduce carrageenan-induced hind paw inflammation in pentobarbital-treated mice: comparison with indomethacin and possible involvement of cannabinoid receptors.
Sandra Holt, Francesca Comelli, Barbara Costa, Christopher J Fowler

Br J Pharmacol· October 2005

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The endocannabinoid signaling system: pharmacological and therapeutic aspects.
Christopher J Fowler, Sandra Holt, Olov Nilsson, Kent-Olov Jonsson, Gunnar Tiger

Pharmacol Biochem Behav· June 2005

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Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase.
Sandra Holt, David Rocksén, Anders Bucht, Gitte Petersen, Harald S Hansen

Life Sci· December 2004

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Anandamide metabolism by fatty acid amide hydrolase in intact C6 glioma cells. Increased sensitivity to inhibition by ibuprofen and flurbiprofen upon reduction of extra- but not intracellular pH.
Sandra Holt, Christopher J Fowler

Naunyn Schmiedebergs Arch Pharmacol· March 2003

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Acidic nonsteroidal anti-inflammatory drugs inhibit rat brain fatty acid amide hydrolase in a pH-dependent manner.
Christopher J Fowler, Sandra Holt, Gunnar Tiger

J Enzyme Inhib Med Chem· February 2003

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