Publications by authors named "Sandra Koen"

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Distribution of C30 carotenoid biosynthesis genes suggests habitat adaptation function in insect-adapted and nomadic Lactobacillaceae.
Tom Eilers, Marie Legein, Jari Temmermans, Jelle Dillen, Ine Vandendriessche, Koen Sandra

Commun Biol· December 2024

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2D-CEX-FcRn-MS to Study Structure/Function Relation of mAb Charge Variants.
Liesa Verscheure, Isabel Vandenheede, Eline De Rore, Mabelle Meersseman, Valerie Hanssens, Koen Sandra

Anal Chem· November 2024

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Systematic analysis of Fc mutations designed to reduce binding to Fc-gamma receptors.
Geoff Hale, Jelle De Vos, Alastair Douglas Davy, Koen Sandra, Ian Wilkinson

MAbs· September 2024

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Multidimensional LC-MS with D multi-method option and parallel middle-up and bottom-up MS acquisition for in-depth characterization of antibodies.
Liesa Verscheure, Shauni Detremmerie, Hilde Stals, Jelle De Vos, Pat Sandra, Koen Sandra

J Chromatogr A· July 2024

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Evaluation of size-exclusion chromatography, multi-angle light scattering detection and mass photometry for the characterization of mRNA.
Jelle De Vos, Kris Morreel, Piotr Alvarez, Helena Vanluchene, Robbe Vankeirsbilck, Koen Sandra

J Chromatogr A· March 2024

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Characterization of mAb size heterogeneity originating from a cysteine to tyrosine substitution using denaturing and native LC-MS.
Isabel Ruppen, Liesa Verscheure, Isabel Vandenheede, Alexia Ortiz, Iván Sánchez de Melo, Koen Sandra

J Pharm Biomed Anal· November 2023

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Glycoproteomics of a Single Protein: Revealing Tens of Thousands of Myozyme Glycoforms by Hybrid HPLC-MS Approaches.
Fiammetta Di Marco, Constantin Blöchl, Wolfgang Esser-Skala, Veronika Schäpertöns, Tao Zhang, Koen Sandra

Mol Cell Proteomics· September 2023

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Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin® following extended physicochemical and functional characterization.
Isabel Ruppen, Marie-Elise Beydon, Clea Solís, Daniel Sacristán, Isabel Vandenheede, Koen Sandra

Biologicals· June 2022

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3D-LC-MS with D Multimethod Option for Fully Automated Assessment of Multiple Attributes of Monoclonal Antibodies Directly from Cell Culture Supernatants.
Liesa Verscheure, Gerd Vanhoenacker, Sonja Schneider, Tom Merchiers, Julie Storms, Koen Sandra

Anal Chem· May 2022

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Multimodal biomarker discovery for active Onchocerca volvulus infection.
Ole Lagatie, Emmanuel Njumbe Ediage, Dirk Van Roosbroeck, Stijn Van Asten, Ann Verheyen, Koen Sandra

PLoS Negl Trop Dis· November 2021

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Quantitative Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis.
Bastiaan L Duivelshof, Steffy Denorme, Koen Sandra, Xiaoxiao Liu, Alain Beck

Pharmaceutics· October 2021

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Monoclonal antibody charge variant characterization by fully automated four-dimensional liquid chromatography-mass spectrometry.
Liesa Verscheure, An Cerdobbel, Pat Sandra, Frederic Lynen, Koen Sandra

J Chromatogr A· September 2021

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What do patients think about opioids? a survey of patient perceptions regarding pain control after shoulder surgery.
Vani Sabesan, Mirelle Dawoud, Kiran Chatha, Sandra Koen, Laila Khoury

JSES Int· September 2021

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An integrated educational and multimodal approach to achieving an opioid-free postoperative course after arthroscopic rotator cuff repair.
Vani J Sabesan, Kiran Chatha, Sandra Koen, Nikolas Echeverry, Wilfredo J Borroto

JSES Int· September 2021

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Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin® following extended physicochemical and functional characterization.
Isabel Ruppen, Marie-Elise Beydon, Clea Solís, Daniel Sacristán, Isabel Vandenheede, Koen Sandra

Biologicals· September 2021

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Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients.
Bart Van Puyvelde, Katleen Van Uytfanghe, Olivier Tytgat, Laurence Van Oudenhove, Ralf Gabriels, Koen Sandra

JACS Au· June 2021

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Middle-up characterization of monoclonal antibodies by online reduction liquid chromatography-mass spectrometry.
Liesa Verscheure, Marie Oosterlynck, An Cerdobbel, Pat Sandra, Frederic Lynen, Koen Sandra

J Chromatogr A· January 2021

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Concussions in Soccer: An Epidemiological Analysis in the Pediatric Population.
Kiran Chatha, Taylor Pruis, Carlos Fernandez Peaguda, Eric Guo, Sandra Koen

Orthop J Sports Med· October 2020

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2-Methyl-pentanoyl-carnitine (2-MPC): a urine biomarker for patent Ascaris lumbricoides infection.
Ole Lagatie, Ann Verheyen, Stijn Van Asten, Maurice R Odiere, Yenny Djuardi, Koen Sandra

Sci Rep· September 2020

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Innovative patient education and pain management protocols to achieve opioid-free shoulder arthroplasty.
Vani J Sabesan, Kiran Chatha, Sandra Koen, Mirelle Dawoud, Gregory Gilot

JSES Int· June 2020

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Determination of variability due to biological and technical variation in urinary extracellular vesicles as a crucial step in biomarker discovery studies.
Eline Oeyen, Hanny Willems, Ruben 't Kindt, Koen Sandra, Kurt Boonen

J Extracell Vesicles· October 2019

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The versatility of heart-cutting and comprehensive two-dimensional liquid chromatography in monoclonal antibody clone selection.
Koen Sandra, Mieke Steenbeke, Isabel Vandenheede, Gerd Vanhoenacker, Pat Sandra

J Chromatogr A· November 2017

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Evaluation of size exclusion chromatography columns packed with sub-3μm particles for the analysis of biopharmaceutical proteins.
Alexandre Goyon, Alain Beck, Olivier Colas, Koen Sandra, Davy Guillarme

J Chromatogr A· May 2017

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Psoralen and Ultraviolet A Light Treatment Directly Affects Phosphatidylinositol 3-Kinase Signal Transduction by Altering Plasma Membrane Packing.
Britt Van Aelst, Rosalie Devloo, Pierre Zachée, Ruben t'Kindt, Koen Sandra

J Biol Chem· November 2016

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Multiple heart-cutting and comprehensive two-dimensional liquid chromatography hyphenated to mass spectrometry for the characterization of the antibody-drug conjugate ado-trastuzumab emtansine.
Koen Sandra, Gerd Vanhoenacker, Isabel Vandenheede, Mieke Steenbeke, Maureen Joseph

J Chromatogr B Analyt Technol Biomed Life Sci· October 2016

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