Publications by authors named "Sanjeev A Datar"

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Pulmonary Vascular Endothelial Dysfunction Is Induced by Nonpulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model.
Jonathan Hyde, Michael A Smith, Naveen Swami, John H Hwang, Yenchun Chao, Sanjeev A Datar

Compr Physiol· December 2025

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Microvascular preservation and cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension.
Michael A Smith, Eleana S Guardado, Jason Boehme, Sanjeev A Datar, Emin Maltepe

Am J Physiol Heart Circ Physiol· October 2025

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Pulmonary Vascular Endothelial Dysfunction is Induced by Non-Pulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model.
Jonathan Hyde, Michael A Smith, Naveen Swami, John H Hwang, Yenchun Chao, Sanjeev A Datar

bioRxiv· October 2025

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Mechanotransductive stabilization of HIF-1α is inhibited by mitochondrial antioxidant therapy in the setting of pulmonary overcirculation.
Jason T Boehme, Sanjeev A Datar, Xutong Sun, Wenhui Gong, Qing Lu

Sci Rep· May 2025

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MicroRNA in pediatric pulmonary hypertension microRNA profiling to inform disease classification, severity, and treatment response in pediatric pulmonary hypertension.
Michael A Smith, Sam Chiacchia, Jason Boehme, Sanjeev A Datar, Emily Morell

Am J Physiol Heart Circ Physiol· January 2025

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The mitochondrial redistribution of ENOS is regulated by AKT1 and dimer status.
Xutong Sun, Santiago Moreno Caceres, Manivannan Yegambaram, Qing Lu, Marissa D Pokharel, Sanjeev A Datar

Nitric Oxide· November 2024

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OMX: A NOVEL OXYGEN DELIVERY BIOTHERAPEUTIC IMPROVES OUTCOMES IN AN OVINE MODEL OF CONTROLLED HEMORRHAGIC SHOCK.
Emin Maltepe, Michael Smith, Jason Boehme, Sanjeev A Datar, Rachel S Hutchings

Shock· July 2024

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Simvastatin restores pulmonary endothelial function in the setting of pulmonary over-circulation.
Jason T Boehme, Xutong Sun, Qing Lu, Jubilee Barton, Xiaomin Wu, Sanjeev A Datar

Nitric Oxide· January 2024

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Respiratory mechanics and gas exchange in an ovine model of congenital heart disease with increased pulmonary blood flow and pressure.
Joao Henrique N Soares, Gary W Raff, Jeffrey R Fineman, Sanjeev A Datar

Front Physiol· June 2023

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HIF-1α promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow.
Jason T Boehme, Catherine J Morris, Samuel R Chiacchia, Wenhui Gong, Katherine Y Wu, Sanjeev A Datar

Sci Rep· January 2021

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Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease.
Terry Zhu, Samuel Chiacchia, Rebecca J Kameny, Antoni Garcia De Herreros, Wenhui Gong, Sanjeev A Datar

Pulm Circ· May 2020

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Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling.
Rebecca Johnson Kameny, Sanjeev A Datar, Jason B Boehme, Catherine Morris, Terry Zhu

Am J Respir Cell Mol Biol· May 2019

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Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.
Jason Boehme, Natacha Le Moan, Rebecca J Kameny, Alexandra Loucks, Michael J Johengen, Sanjeev A Datar

PLoS Biol· January 2019

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Analysis of the microRNA signature driving adaptive right ventricular hypertrophy in an ovine model of congenital heart disease.
Rebecca Johnson Kameny, Youping He, Terry Zhu, Wenhui Gong, Gary W Raff, Sanjeev A Datar

Am J Physiol Heart Circ Physiol· October 2018

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Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic.
Jason Boehme, Natacha Le Moan, Rebecca J Kameny, Alexandra Loucks, Michael J Johengen, Sanjeev A Datar

PLoS Biol· October 2018

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KLF2-mediated disruption of PPAR-γ signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow.
Catherine J Morris, Rebecca J Kameny, Jason Boehme, Wenhui Gong, Youping He, Sanjeev A Datar

Am J Physiol Heart Circ Physiol· July 2018

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Lymphatic dysfunction in critical illness.
Edmund Burke, Sanjeev A Datar

Curr Opin Pediatr· June 2018

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Altered Carnitine Homeostasis in Children With Increased Pulmonary Blood Flow Due to Ventricular Septal Defects.
Stephen M Black, Aida Field-Ridley, Shruti Sharma, Sanjiv Kumar, Roberta L Keller, Sanjeev A Datar

Pediatr Crit Care Med· October 2017

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Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation.
Jason Boehme, Xutong Sun, Kathryn V Tormos, Wenhui Gong, Manuela Kellner, Sanjeev A Datar

Am J Physiol Heart Circ Physiol· October 2016

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Disrupted NOS signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow.
Sanjeev A Datar, Wenhui Gong, Youping He, Michael Johengen, Rebecca J Kameny

Am J Physiol Heart Circ Physiol· July 2016

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Right ventricular nitric oxide signaling in an ovine model of congenital heart disease: a preserved fetal phenotype.
Rebecca Johnson Kameny, Youping He, Catherine Morris, Christine Sun, Michael Johengen, Sanjeev A Datar

Am J Physiol Heart Circ Physiol· July 2015

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Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress.
Christine M Gross, Saurabh Aggarwal, Sanjiv Kumar, Jing Tian, Anita Kasa, Sanjeev A Datar

J Cell Physiol· November 2014

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Preoperative B-type natriuretic peptide levels are associated with outcome after total cavopulmonary connection (Fontan).
Monique Radman, Roberta L Keller, Peter Oishi, Sanjeev A Datar, Kari Wellnitz

J Thorac Cardiovasc Surg· July 2014

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Altered reactivity and nitric oxide signaling in the isolated thoracic duct from an ovine model of congenital heart disease with increased pulmonary blood flow.
Sanjeev A Datar, Peter E Oishi, Wenhui Gong, Stephen H Bennett, Christine E Sun

Am J Physiol Heart Circ Physiol· April 2014

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Adaptive right ventricular performance in response to acutely increased afterload in a lamb model of congenital heart disease: evidence for enhanced Anrep effect.
Rebecca C Johnson, Sanjeev A Datar, Peter E Oishi, Stephen Bennett, Jun Maki

Am J Physiol Heart Circ Physiol· April 2014

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