Publications by authors named "Sarah Auclair"

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Rational design of next-generation filovirus vaccines combining glycoprotein stabilization and nanoparticle display with glycan modification.
Yi-Zong Lee, Yi-Nan Zhang, Maddy L Newby, Garrett Ward, Keegan Braz Gomes, Sarah Auclair

Nat Commun· December 2025

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Rational design of next-generation filovirus vaccines through glycoprotein stabilization, nanoparticle display, and glycan modification.
Yi-Zong Lee, Yi-Nan Zhang, Maddy L Newby, Garrett Ward, Keegan Braz Gomes, Sarah Auclair

bioRxiv· August 2025

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Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.
Yi-Zong Lee, Jerome Han, Yi-Nan Zhang, Garrett Ward, Keegan Braz Gomes, Sarah Auclair

Nat Commun· November 2024

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A Single-Component Multilayered Self-Assembling Protein Nanoparticle Vaccine Based on Extracellular Domains of Matrix Protein 2 against Both Influenza A and B.
Yi-Nan Zhang, Keegan Braz Gomes, Yi-Zong Lee, Garrett Ward, Bomin Xie, Sarah Auclair

Vaccines (Basel)· August 2024

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Virus-like nanoparticle vaccines for inducing long-lasting immunity against infectious diseases.
Yi-Nan Zhang, Sarah Auclair, Jiang Zhu

Natl Sci Rev· April 2024

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A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers.
Yi-Zong Lee, Jerome Han, Yi-Nan Zhang, Garrett Ward, Keegan Braz Gomes, Sarah Auclair

bioRxiv· March 2024

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Co-Delivery of a Novel Lipidated TLR7/8 Agonist and Hemagglutinin-Based Influenza Antigen Using Silica Nanoparticles Promotes Enhanced Immune Responses.
Walid M Abdelwahab, Sarah Auclair, Timothy Borgogna, Karthik Siram, Alexander Riffey

Pharmaceutics· January 2024

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Single-Component Multilayered Self-Assembling Protein Nanoparticles Displaying Extracellular Domains of Matrix Protein 2 as a Pan-influenza A Vaccine.
Keegan Braz Gomes, Yi-Nan Zhang, Yi-Zong Lee, Mor Eldad, Alexander Lim, Sarah Auclair

ACS Nano· December 2023

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AF4 and PEG Precipitation as Predictive Assays for Antibody Self-Association.
Itzel Condado-Morales, Viktoria Sokolova, Per-Olof Wahlund, Kristine E Heding, Sarah Auclair

Mol Pharm· February 2023

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A single molecular descriptor to predict solution behavior of therapeutic antibodies.
Jonathan S Kingsbury, Amandeep Saini, Sarah Marie Auclair, Li Fu, Michaela M Lantz

Sci Adv· August 2020

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Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection.
Sarah Auclair, Fengliang Liu, Qingli Niu, Wei Hou, Gavin Churchyard

PLoS Pathog· February 2018

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Otoferlin acts as a Ca sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
Nicolas Michalski, Juan D Goutman, Sarah Marie Auclair, Jacques Boutet de Monvel, Margot Tertrais

Elife· November 2017

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Dilation of fusion pores by crowding of SNARE proteins.
Zhenyong Wu, Oscar D Bello, Sathish Thiyagarajan, Sarah Marie Auclair, Wensi Vennekate

Elife· March 2017

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Loss of immune control in HIV-infected patients: how does mucosal candidiasis occur?
Sarah Auclair, Fengliang Liu, Haitao Hu

Future Microbiol· January 2017

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Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in guinea pigs during latent HSV-2 genital infection.
Clarice L Perry, Brianne N Banasik, Summer R Gorder, Jingya Xia, Sarah Auclair

J Immunol Methods· December 2016

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Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains.
Zhenyong Wu, Sarah M Auclair, Oscar Bello, Wensi Vennekate, Natasha R Dudzinski

Sci Rep· June 2016

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Sequential Dysfunction and Progressive Depletion of Candida albicans-Specific CD4 T Cell Response in HIV-1 Infection.
Fengliang Liu, Xiuzhen Fan, Sarah Auclair, Monique Ferguson, Jiaren Sun

PLoS Pathog· June 2016

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Therapeutic Efficacy of a Subunit Vaccine in Controlling Chronic Trypanosoma cruzi Infection and Chagas Disease Is Enhanced by Glutathione Peroxidase Over-Expression.
Shivali Gupta, Charity Smith, Sarah Auclair, Anahi De Jesus Delgadillo, Nisha Jain Garg

PLoS One· May 2016

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Using ApoE Nanolipoprotein Particles To Analyze SNARE-Induced Fusion Pores.
Oscar D Bello, Sarah M Auclair, James E Rothman, Shyam S Krishnakumar

Langmuir· March 2016

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Calcium sensitive ring-like oligomers formed by synaptotagmin.
Jing Wang, Oscar Bello, Sarah M Auclair, Jing Wang, Jeff Coleman

Proc Natl Acad Sci U S A· September 2014

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Analysis of SecA dimerization in solution.
Andy J Wowor, Yuetian Yan, Sarah M Auclair, Dongmei Yu, Jun Zhang

Biochemistry· May 2014

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Interleukin-3-deficient mice have increased resistance to blood-stage malaria.
Sarah R Auclair, Kenneth E Roth, Bryan L Saunders, Kathryn M Ogborn, Abdalla A Sheikh

Infect Immun· March 2014

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Defining the solution state dimer structure of Escherichia coli SecA using Förster resonance energy transfer.
Sarah M Auclair, Donald B Oliver, Ishita Mukerji

Biochemistry· April 2013

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Signal peptidase I: cleaving the way to mature proteins.
Sarah M Auclair, Meera K Bhanu, Debra A Kendall

Protein Sci· January 2012

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Mapping of the signal peptide-binding domain of Escherichia coli SecA using Förster resonance energy transfer.
Sarah M Auclair, Julia P Moses, Monika Musial-Siwek, Debra A Kendall, Donald B Oliver

Biochemistry· February 2010

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