Publications by authors named "Sarah Batt"

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Developing pyrazole-oxadiazole conjugates as potent anti-tubercular agents: an and approach.
Sethu Arun Kumar, Gurdayal Besra, Sarah Batt, V M Chandrashekar, Manisha Singh

RSC Med Chem· December 2025

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Novel hybrids of 1,2,3-triazole-benzoxazole: design, synthesis, and assessment of DprE1 enzyme inhibitors using fluorometric assay and computational analysis.
Manisha Singh, Sarah M Batt, Christian S C Canales, Fernando R Pavan, Sethu Arun Kumar

J Enzyme Inhib Med Chem· December 2024

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Cryo-electron microscopy structure of the di-domain core of polyketide synthase 13, essential for mycobacterial mycolic acid synthesis.
Hannah E Johnston, Sarah M Batt, Alistair K Brown, Christos G Savva, Gurdyal S Besra

Microbiology (Reading)· October 2024

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Top five unanswered questions in bacterial cell wall research.
Sarah M Batt, Katherine A Abrahams, Gurdyal S Besra

Cell Surf· June 2024

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Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis.
Shan Gao, Fangyu Wu, Sudagar S Gurcha, Sarah M Batt, Gurdyal S Besra

Nat Microbiol· April 2024

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Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of .
Yicheng Gong, Chuancun Wei, Jun Wang, Nengjiang Mu, Qinhong Lu, Sarah M Batt

Proc Natl Acad Sci U S A· June 2023

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DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid.
Katherine A Abrahams, Sarah M Batt, Sudagar S Gurcha, Natacha Veerapen, Ghader Bashiri

Nat Commun· June 2023

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Assay development and inhibition of the -DprE2 essential reductase from .
Sarah M Batt, Szilvi Toth, Beatriz Rodriguez, Katherine A Abrahams, Natacha Veerapen

Microbiology (Reading)· January 2023

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Vanoxerine kills mycobacteria through membrane depolarization and efflux inhibition.
Alexander D H Kingdon, Asti-Rochelle Meosa-John, Sarah M Batt, Gurdyal S Besra

Front Microbiol· January 2023

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Identification of thiophene-benzenesulfonamide derivatives for the treatment of multidrug-resistant tuberculosis.
Rongfei Qin, Pengxu Wang, Bin Wang, Lei Fu, Sarah M Batt

Eur J Med Chem· March 2022

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The multi-target aspect of an MmpL3 inhibitor: The BM212 series of compounds bind EthR2, a transcriptional regulator of ethionamide activation.
Alice R Moorey, Alejandro Cabanillas, Sarah M Batt, Sonja Ghidelli-Disse, Beatriz Urones

Cell Surf· December 2021

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A multi-targeting pre-clinical candidate against drug-resistant tuberculosis.
Parvinder Kaur, Vijay Potluri, Vijay Kamal Ahuja, C N Naveenkumar, Ramya Vadageri Krishnamurthy, Sarah M Batt

Tuberculosis (Edinb)· July 2021

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Discovery of Novel Thiophene-arylamide Derivatives as DprE1 Inhibitors with Potent Antimycobacterial Activities.
Pengxu Wang, Sarah M Batt, Bin Wang, Lei Fu, Rongfei Qin

J Med Chem· May 2021

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Antibiotics and resistance: the two-sided coin of the mycobacterial cell wall.
Sarah M Batt, Christopher E Burke, Alice R Moorey, Gurdyal S Besra

Cell Surf· December 2020

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Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB-AcpM.
Lu Zhang, Yao Zhao, Ruogu Gao, Jun Li, Xiuna Yang, Sarah M Batt

Protein Cell· July 2020

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Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Lu Zhang, Yao Zhao, Yan Gao, Lijie Wu, Ruogu Gao, Sarah M Batt

Science· June 2020

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The thick waxy coat of mycobacteria, a protective layer against antibiotics and the host's immune system.
Sarah M Batt, David E Minnikin, Gurdyal S Besra

Biochem J· May 2020

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Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones.
Peng Li, Bin Wang, Xinwei Zhang, Sarah M Batt, Gurdyal S Besra

Eur J Med Chem· December 2018

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Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.
Adrian Richter, Ines Rudolph, Ute Möllmann, Kerstin Voigt, Chun-Wa Chung, Sarah Batt

Sci Rep· September 2018

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Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes.
Renhe Liu, Xiaoxuan Lyu, Sarah M Batt, Mei-Hui Hsu, Michael B Harbut

Angew Chem Int Ed Engl· October 2017

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Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase.
Sarah M Batt, Monica Cacho Izquierdo, Julia Castro Pichel, Christopher J Stubbs, Laura Vela-Glez Del Peral

ACS Infect Dis· December 2015

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Identification of a small molecule with activity against drug-resistant and persistent tuberculosis.
Feng Wang, Dhinakaran Sambandan, Rajkumar Halder, Jianing Wang, Sarah M Batt

Proc Natl Acad Sci U S A· July 2013

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Final year student nurses' experiences of wound care: an evaluation.
Karen Ousey, John Stephenson, Leanne Cook, Laura Kinsey, Sarah Batt

Br J Community Nurs· March 2013

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The ppm operon is essential for acylation and glycosylation of lipoproteins in Corynebacterium glutamicum.
Niloofar Mohiman, Manuela Argentini, Sarah M Batt, David Cornu, Muriel Masi

PLoS One· February 2013

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Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors.
Sarah M Batt, Talat Jabeen, Veemal Bhowruth, Lee Quill, Peter A Lund

Proc Natl Acad Sci U S A· July 2012

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