Publications by authors named "Sarah Heeson"

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Pharmacokinetic bioequivalence of the fixed-dose combination of pertuzumab and trastuzumab administered subcutaneously using a handheld syringe or an on-body delivery system.
Chris Wynne, Bei Wang, Rong Deng, Junyi Li, Daniel Eiger, Sarah Heeson

J Cancer Res Clin Oncol· June 2025

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heredERA Breast Cancer: a phase III, randomized, open-label study evaluating the efficacy and safety of giredestrant plus the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection in patients with previously untreated HER2-positive, estrogen receptor-positive locally advanced or metastatic breast cancer.
Sherko Kuemmel, Catherine Harper-Wynne, Yeon Hee Park, Fábio Franke, Michelino de Laurentiis, Sarah Heeson

BMC Cancer· May 2024

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Pertuzumab, trastuzumab, and chemotherapy in HER2-positive gastric/gastroesophageal junction cancer: end-of-study analysis of the JACOB phase III randomized clinical trial.
Josep Tabernero, Paulo M Hoff, Lin Shen, Atsushi Ohtsu, Manish A Shah, Sarah Heeson

Gastric Cancer· January 2023

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Incidence and severity of anaphylaxis and hypersensitivity in trials of intravenous pertuzumab plus trastuzumab or the fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection for HER2-positive breast cancer.
Sandra M Swain, Antoinette R Tan, Luca Gianni, Sherko Kuemmel, Chau T Dang, Sarah Heeson

Eur J Cancer· January 2023

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Six-year absolute invasive disease-free survival benefit of adding adjuvant pertuzumab to trastuzumab and chemotherapy for patients with early HER2-positive breast cancer: A Subpopulation Treatment Effect Pattern Plot (STEPP) analysis of the APHINITY (BIG 4-11) trial.
Richard D Gelber, Xin V Wang, Bernard F Cole, David Cameron, Fatima Cardoso, Sarah Heeson

Eur J Cancer· May 2022

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Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a randomised, open-label, multicentre, non-inferiority, phase 3 study.
Antoinette R Tan, Seock-Ah Im, André Mattar, Ramon Colomer, Daniil Stroyakovskii, Sarah Heeson

Lancet Oncol· January 2021

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Development of a Subcutaneous Fixed-Dose Combination of Pertuzumab and Trastuzumab: Results From the Phase Ib Dose-Finding Study.
Whitney P Kirschbrown, Chris Wynne, Matts Kågedal, Russ Wada, Hanbin Li, Sarah Heeson

J Clin Pharmacol· May 2019

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Randomized Phase III Trial of Trastuzumab Plus Capecitabine With or Without Pertuzumab in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer Who Experienced Disease Progression During or After Trastuzumab-Based Therapy.
Ander Urruticoechea, Mohammed Rizwanullah, Seock-Ah Im, Antonio Carlos Sánchez Ruiz, István Láng, Sarah Heeson

J Clin Oncol· September 2017

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Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer.
Sandra M Swain, José Baselga, Sung-Bae Kim, Jungsil Ro, Vladimir Semiglazov, Sarah Heeson

N Engl J Med· February 2015

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Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops.
Adele Murrell, Sarah Heeson, Wolf Reik

Nat Genet· August 2004

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An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype.
Adele Murrell, Sarah Heeson, Wendy N Cooper, Eleanor Douglas, Sophia Apostolidou

Hum Mol Genet· January 2004

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