Publications by authors named "Sarah Jolly"

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Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis.
Oliver J Ziff, Gustavo Morrone Parfitt, Sarah Jolly, Jackie M Casey, Lucy Granat

Mol Neurodegener· June 2025

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Microglial Expression of the Wnt Signaling Modulator Differs between Human Alzheimer's Disease Brains and Mouse Neurodegeneration Models.
Nozie D Aghaizu, Sarah Jolly, Satinder K Samra, Bernadett Kalmar, Katleen Craessaerts

eNeuro· January 2023

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A primary rodent triculture model to investigate the role of glia-neuron crosstalk in regulation of neuronal activity.
Leela Phadke, Dawn H W Lau, Nozie D Aghaizu, Shania Ibarra, Carmen M Navarron, Sarah Jolly

Front Aging Neurosci· December 2022

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Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters.
Ernest Palomer, Núria Martín-Flores, Sarah Jolly, Patricia Pascual-Vargas, Stefano Benvegnù

Mol Psychiatry· July 2022

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Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit.
Nicky J Willis, William Mahy, James Sipthorp, Yuguang Zhao, Hannah L Woodward, Sarah Jolly

J Med Chem· May 2022

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Small-molecule inhibitors of carboxylesterase Notum.
Yuguang Zhao, Sarah Jolly, Stefano Benvegnu, E Yvonne Jones, Paul V Fish

Future Med Chem· June 2021

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Single-Cell Quantification of mRNA Expression in The Human Brain.
Sarah Jolly, Verena Lang, Viktor Hendrik Koelzer, Carlo Sala Frigerio, Lorenza Magno

Sci Rep· August 2019

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G protein-coupled receptor 37-like 1 modulates astrocyte glutamate transporters and neuronal NMDA receptors and is neuroprotective in ischemia.
Sarah Jolly, Narges Bazargani, Alejandra C Quiroga, Nigel P Pringle, David Attwell

Glia· January 2018

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Combining Double Fluorescence In Situ Hybridization with Immunolabelling for Detection of the Expression of Three Genes in Mouse Brain Sections.
Sarah Jolly, Alexander Fudge, Nigel Pringle, William D Richardson, Huiliang Li

J Vis Exp· March 2016

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RORalpha, a key to the development and functioning of the brain.
Sarah Jolly, Nathalie Journiac, Béatrice Vernet-der Garabedian, Jean Mariani

Cerebellum· June 2012

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Cell-autonomous and non-cell-autonomous neuroprotective functions of RORα in neurons and astrocytes during hypoxia.
Sarah Jolly, Nathalie Journiac, Frédéric Naudet, Vanessa Gautheron, Jean Mariani

J Neurosci· October 2011

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The nuclear receptor ROR(alpha) exerts a bi-directional regulation of IL-6 in resting and reactive astrocytes.
Nathalie Journiac, Sarah Jolly, Christopher Jarvis, Vanessa Gautheron, Monique Rogard

Proc Natl Acad Sci U S A· December 2009

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