Publications by authors named "Sarah Keane"

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Structural Features Within Precursor microRNA-20a Regulate Dicer-TRBP Processing.
Yaping Liu, Cade T Harkner, Megan N Westwood, Aldrex Munsayac, Sarah C Keane

J Mol Biol· December 2025

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Integrated and experimental screening identifies novel ligands that target precursor microRNA-31 at the dicer cleavage site.
Grace Arhin, Lily Haghpassand, Sarah C Keane

RSC Med Chem· October 2025

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Structure guided discovery of small molecule ligands targeting the oncomiR-1 NPSL2 hairpin.
Grace Arhin, Sarah C Keane

Sci Rep· August 2025

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Integrated and experimental screening identifies novel ligands that target precursor microRNA-31 at the Dicer cleavage site.
Grace Arhin, Lily Haghpassand, Sarah C Keane

bioRxiv· June 2025

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Structural features within precursor microRNA-20a regulate Dicer-TRBP processing.
Yaping Liu, Cade T Harkner, Megan N Westwood, Aldrex Munsayac, Sarah C Keane

bioRxiv· May 2025

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discovery of compounds targeting NPSL2: a regulatory element in the human oncomiR-1 primary microRNA.
Grace Arhin, Sarah C Keane

bioRxiv· May 2025

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Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering.
Aldrex Munsayac, Wellington C Leite, Jesse B Hopkins, Ian Hall, Hugh M O'Neill, Sarah C Keane

Structure· April 2025

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Functional Validation of SAM Riboswitch Element A from .
Ian Hall, Kaitlyn Zablock, Raeleen Sobetski, Chase A Weidmann, Sarah C Keane

Biochemistry· October 2024

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Selective deuteration of an RNA:RNA complex for structural analysis using small-angle scattering.
Aldrex Munsayac, Wellington C Leite, Jesse B Hopkins, Ian Hall, Hugh M O'Neill, Sarah C Keane

bioRxiv· September 2024

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Use of steric blocking antisense oligonucleotides for the targeted inhibition of junction containing precursor microRNAs.
Sicong Ma, Samantha A Howden, Sarah C Keane

bioRxiv· April 2024

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Structure of pre-miR-31 reveals an active role in Dicer-TRBP complex processing.
Sicong Ma, Anita Kotar, Ian Hall, Scott Grote, Silvi Rouskin, Sarah C Keane

Proc Natl Acad Sci U S A· September 2023

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Structure of pre-miR-31 reveals an active role in Dicer processing.
Sicong Ma, Anita Kotar, Scott Grote, Silvi Rouskin, Sarah C Keane

bioRxiv· January 2023

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Solution Structure of NPSL2, A Regulatory Element in the oncomiR-1 RNA.
Yaping Liu, Aldrex Munsayac, Ian Hall, Sarah C Keane

J Mol Biol· September 2022

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pH dependence of C•A, G•A and A•A mismatches in the stem of precursor microRNA-31.
Anita Kotar, Sicong Ma, Sarah C Keane

Biophys Chem· April 2022

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NMR chemical shift assignments of RNA oligonucleotides to expand the RNA chemical shift database.
Yaping Liu, Anita Kotar, Tracy L Hodges, Kyrillos Abdallah, Mallak H Taleb, Sarah C Keane

Biomol NMR Assign· October 2021

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Setting priorities for people with intellectual disability/intellectual developmental disorders across the lifespan: a call to action by the World Psychiatric Association.
Ashok Roy, Ken Courtenay, Mahesh Odiyoor, Patricia Walsh, Sarah Keane

BJPsych Int· August 2021

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Single center analysis of patients with H1N1 vaccine-related narcolepsy and sporadic narcolepsy presenting over the same time period.
Damien Ferguson, Sarah Wrigley, Elaine Purcell, Sarah Keane, Ben McGinn

J Clin Sleep Med· May 2021

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A Tale of Two Transitions: The Unfolding Mechanism of the prfA RNA Thermosensor.
Huaqun Zhang, Ian Hall, Amos J Nissley, Kyrillos Abdallah, Sarah C Keane

Biochemistry· December 2020

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Advanced approaches for elucidating structures of large RNAs using NMR spectroscopy and complementary methods.
Anita Kotar, Hannah N Foley, Kirk M Baughman, Sarah C Keane

Methods· November 2020

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Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches.
Wipapat Kladwang, Ved V Topkar, Bei Liu, Ramya Rangan, Tracy L Hodges, Sarah C Keane

Biochemistry· June 2020

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Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences.
Jennifer L Meagher, Matthew Takata, Daniel Gonçalves-Carneiro, Sarah C Keane, Antoine Rebendenne

Proc Natl Acad Sci U S A· November 2019

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Advances that facilitate the study of large RNA structure and dynamics by nuclear magnetic resonance spectroscopy.
Huaqun Zhang, Sarah C Keane

Wiley Interdiscip Rev RNA· September 2019

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Are patterns of violence and aggression at presentation in patients with first-episode psychosis temporally stable? A comparison of 2 cohorts.
Sarah Keane, Attila Szigeti, Felicity Fanning, Mary Clarke

Early Interv Psychiatry· August 2019

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Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach.
Kaiming Zhang, Sarah C Keane, Zhaoming Su, Rossitza N Irobalieva, Muyuan Chen

Structure· March 2018

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NMR Studies of the Structure and Function of the HIV-1 5'-Leader.
Sarah C Keane, Michael F Summers

Viruses· December 2016

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