Publications by authors named "Sarah L Noton"

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Minigenome System to Study Respiratory Syncytial Virus Transcription Versus Genome Replication.
Heesu Kim, Sarah L Noton

Methods Mol Biol· August 2025

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In Vitro Biochemical Assays to Study Respiratory Syncytial Virus Polymerase Activities.
Sarah L Noton, Barbara Ludeke

Methods Mol Biol· August 2025

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Distinctive features of the respiratory syncytial virus priming loop compared to other non-segmented negative strand RNA viruses.
Tessa N Cressey, Afzaal M Shareef, Victoria A Kleiner, Sarah L Noton, Patrick O Byrne

PLoS Pathog· June 2022

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Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts.
Molly R Braun, Sarah L Noton, Emmeline L Blanchard, Afzaal Shareef, Philip J Santangelo

PLoS Pathog· May 2021

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EDP-938, a novel nucleoprotein inhibitor of respiratory syncytial virus, demonstrates potent antiviral activities in vitro and in a non-human primate model.
Michael H J Rhodin, Nicole V McAllister, Jonathan Castillo, Sarah L Noton, Rachel Fearns

PLoS Pathog· March 2021

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Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection.
Emmeline L Blanchard, Molly R Braun, Aaron W Lifland, Barbara Ludeke, Sarah L Noton

PLoS Pathog· October 2020

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Killing two birds with one stone: How the respiratory syncytial virus polymerase initiates transcription and replication.
Sarah L Noton, Chadene Z Tremaglio, Rachel Fearns

PLoS Pathog· February 2019

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Dual Catalytic Synthesis of Antiviral Compounds Based on Metallocarbene-Azide Cascade Chemistry.
Bren Jordan P Atienza, Lionel D Jensen, Sarah L Noton, Anil Kumar Victoria Ansalem, Tom Hobman

J Org Chem· July 2018

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Mechanism for de novo initiation at two sites in the respiratory syncytial virus promoter.
Tessa N Cressey, Sarah L Noton, Kartikeya Nagendra, Molly R Braun, Rachel Fearns

Nucleic Acids Res· July 2018

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RNA elongation by respiratory syncytial virus polymerase is calibrated by conserved region V.
Molly R Braun, Laure R Deflubé, Sarah L Noton, Michael E Mawhorter, Chadene Z Tremaglio

PLoS Pathog· December 2017

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Respiratory Syncytial Virus Inhibitor AZ-27 Differentially Inhibits Different Polymerase Activities at the Promoter.
Sarah L Noton, Kartikeya Nagendra, Ewan F Dunn, Michael E Mawhorter, Qin Yu

J Virol· August 2015

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Initiation and regulation of paramyxovirus transcription and replication.
Sarah L Noton, Rachel Fearns

Virology· May 2015

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Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis.
Diane C Munday, Weining Wu, Nikki Smith, Jenna Fix, Sarah Louise Noton

J Virol· January 2015

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Factors affecting de novo RNA synthesis and back-priming by the respiratory syncytial virus polymerase.
Sarah L Noton, Waleed Aljabr, Julian A Hiscox, David A Matthews, Rachel Fearns

Virology· August 2014

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The respiratory syncytial virus polymerase has multiple RNA synthesis activities at the promoter.
Sarah L Noton, Laure R Deflubé, Chadene Z Tremaglio, Rachel Fearns

PLoS Pathog· April 2013

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Respiratory syncytial virus polymerase can initiate transcription from position 3 of the leader promoter.
Chadene Z Tremaglio, Sarah L Noton, Laure R Deflubé, Rachel Fearns

J Virol· March 2013

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The first two nucleotides of the respiratory syncytial virus antigenome RNA replication product can be selected independently of the promoter terminus.
Sarah L Noton, Rachel Fearns

RNA· October 2011

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Evidence that the polymerase of respiratory syncytial virus initiates RNA replication in a nontemplated fashion.
Sarah L Noton, Vanessa M Cowton, Chadene R Zack, David R McGivern, Rachel Fearns

Proc Natl Acad Sci U S A· June 2010

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Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway.
Emily A Bruce, Liz Medcalf, Colin M Crump, Sarah L Noton, Amanda D Stuart

Virology· August 2009

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Studies of an influenza A virus temperature-sensitive mutant identify a late role for NP in the formation of infectious virions.
Sarah L Noton, Martha Simpson-Holley, Elizabeth Medcalf, Helen M Wise, Edward C Hutchinson

J Virol· January 2009

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Identification of the domains of the influenza A virus M1 matrix protein required for NP binding, oligomerization and incorporation into virions.
Sarah L Noton, Elizabeth Medcalf, Dawn Fisher, Anne E Mullin, Debra Elton

J Gen Virol· August 2007

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