Publications by authors named "Sarah L Rea"

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Randomised trial of genetic testing and targeted intervention to prevent the development and progression of Paget's disease of bone.
Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Owen Cronin, Sarah L Rea

Ann Rheum Dis· March 2024

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Functional and structural consequences of TBK1 missense variants in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Yuval Gurfinkel, Nicole Polain, Krushna Sonar, Penelope Nice, Ricardo L Mancera, Sarah Lyn Rea

Neurobiol Dis· November 2022

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The SQSTM1/p62 UBA domain regulates Ajuba localisation, degradation and NF-κB signalling function.
Melanie A Sultana, Carmel Cluning, Wai-Sin Kwong, Nicole Polain, Nathan J Pavlos, Sarah L Rea

PLoS One· January 2022

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The role of sequestosome 1/p62 protein in amyotrophic lateral sclerosis and frontotemporal dementia pathogenesis.
Adriana Delice Foster, Sarah Lyn Rea

Neural Regen Res· December 2020

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The endoplasmic reticulum-associated protein, OS-9, behaves as a lectin in targeting the immature calcium-sensing receptor.
Bryan K Ward, Sarah L Rea, Aaron L Magno, Bernadette Pedersen, Suzanne J Brown

J Cell Physiol· January 2018

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The Changing Presentation of Paget's Disease of Bone in Australia, A High Prevalence Region.
Cameron Britton, Suzanne Brown, Lynley Ward, Sarah L Rea, Thomas Ratajczak

Calcif Tissue Int· December 2017

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Bafilomycin A1 Attenuates Osteoclast Acidification and Formation, Accompanied by Increased Levels of SQSTM1/p62 Protein.
Sipin Zhu, Sarah L Rea, Taksum Cheng, Hao Tian Feng, John P Walsh

J Cell Biochem· June 2016

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SQSTM1 mutations--bridging Paget disease of bone and ALS/FTLD.
Sarah L Rea, Veronika Majcher, Mark S Searle, Rob Layfield

Exp Cell Res· July 2014

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Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function.
Alice Goode, Jed E Long, Barry Shaw, Stuart H Ralston, Micaela Rios Visconti, Sarah L Rea

Biochim Biophys Acta· July 2014

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Common susceptibility alleles and SQSTM1 mutations predict disease extent and severity in a multinational study of patients with Paget's disease.
Omar M E Albagha, Micaela Rios Visconti, Nerea Alonso, Sachin Wani, Kirsteen Goodman, Sarah L Rea

J Bone Miner Res· November 2013

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New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Paget's disease of bone.
Sarah L Rea, John P Walsh, Robert Layfield, Thomas Ratajczak, Jiake Xu

Endocr Rev· August 2013

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The helix 1-3 loop in the glucocorticoid receptor LBD is a regulatory element for FKBP cochaperones.
Carmel Cluning, Bryan K Ward, Sarah L Rea, Ajanthy Arulpragasam, Peter J Fuller

Mol Endocrinol· July 2013

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The S349T mutation of SQSTM1 links Keap1/Nrf2 signalling to Paget's disease of bone.
Tao Wright, Sarah L Rea, Alice Goode, Andrew J Bennett, Thomas Ratajczak

Bone· February 2013

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Genome-wide association identifies three new susceptibility loci for Paget's disease of bone.
Omar M E Albagha, Sachin E Wani, Micaela R Visconti, Nerea Alonso, Kirsteen Goodman, Sarah L Rea

Nat Genet· May 2011

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Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62, TRAF6, CYLD, and IkappaBalpha signaling cascades.
Estabelle Ang, Nathan J Pavlos, Sarah L Rea, Ming Qi, Tracy Chai

J Cell Physiol· August 2009

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Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding.
Sarah L Rea, John P Walsh, Lynley Ward, Aaron L Magno, Bryan K Ward

J Bone Miner Res· July 2009

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A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype.
Sarah L Rea, John P Walsh, Lynley Ward, Kirk Yip, Bryan K Ward

J Bone Miner Res· July 2006

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