Publications by authors named "Sarah Sasse"

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Inflammatory cytokines promote interferon regulatory factor (IRF) transcriptional activity in human pulmonary epithelial cells through the induction of IRF1 by nuclear factor-κB.
Amandah Necker-Brown, Mahmoud M Mostafa, Andrei Georgescu, Andrew J Thorne, Priyanka Chandramohan, Sarah K Sasse

PLoS One· December 2025

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NF-κB-dependent GR cistrome redistribution recruits GR to inflammatory genes but correlates with lesser glucocorticoid-mediated repression.
Mahmoud M Mostafa, Amandah Necker-Brown, Alex Gao, Andrew J Thorne, Akanksha Bansal, Sarah K Sasse

iScience· December 2025

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Differential RELA and GR recruitment to the BIRC3/BIRC2 locus: Molecular insight as to combinatorial regulation by proinflammatory cytokines and glucocorticoid.
Andrew J Thorne, Alex Gao, Amandah Necker-Brown, Akanksha Bansal, Keerthana Kalyanaraman, Sarah K Sasse

Mol Pharmacol· October 2025

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Functional Variant Discovery Identifies a Novel Genetic Link Between , Wood Smoke, and Asthma.
Arnav Gupta, Amber Dahlin, Alejandra Macario, Fabienne Gally, Michael R Weaver, Sarah K Sasse

Am J Respir Cell Mol Biol· September 2025

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Enhancer RNA transcription pinpoints functional genetic variants linked to asthma.
Sarah K Sasse, Amber Dahlin, Lynn Sanford, Margaret A Gruca, Arnav Gupta

Nat Commun· March 2025

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Progressive lung fibrosis: reprogramming a genetically vulnerable bronchoalveolar epithelium.
James P Bridges, Eszter K Vladar, Jonathan S Kurche, Andrei Krivoi, Ian T Stancil, Sarah K Sasse

J Clin Invest· January 2025

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Inducible gene expression of IκB-kinase ε is dependent on nuclear factor-κB in human pulmonary epithelial cells.
Amandah Necker-Brown, Cora Kooi, Andrew J Thorne, Akanksha Bansal, Mahmoud M Mostafa, Sarah K Sasse

Biochem J· July 2024

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Noncoding SNPs decrease expression of FABP5 during COPD exacerbations.
Manale El Kharbili, Sarah K Sasse, Lynn Sanford, Sean Jacobson, Katja Aviszus

J Clin Invest· December 2023

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Determination of steady-state transcriptome modifications associated with repeated homotypic stress in the rat rostral posterior hypothalamic region.
Serge Campeau, Connor McNulty, Jacob T Stanley, Anthony N Gerber, Sarah K Sasse

Front Neurosci· June 2023

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Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of and in Idiopathic Pulmonary Fibrosis.
Raphael Borie, Jonathan Cardwell, Iain R Konigsberg, Camille M Moore, Weiming Zhang, Sarah K Sasse

Am J Respir Crit Care Med· November 2022

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Integrated genomics approaches identify transcriptional mediators and epigenetic responses to Afghan desert particulate matter in small airway epithelial cells.
Arnav Gupta, Sarah K Sasse, Reena Berman, Margaret A Gruca, Robin D Dowell

Physiol Genomics· October 2022

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Macrophage programming is regulated by a cooperative interaction between fatty acid binding protein 5 and peroxisome proliferator-activated receptor γ.
Manale El Kharbili, Katja Aviszus, Sarah K Sasse, Xiaoyun Zhao, Karina A Serban

FASEB J· May 2022

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Interplay between nuclear factor-κB, p38 MAPK, and glucocorticoid receptor signaling synergistically induces functional TLR2 in lung epithelial cells.
Akanksha Bansal, Mahmoud M Mostafa, Cora Kooi, Sarah K Sasse, Aubrey N Michi

J Biol Chem· April 2022

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Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics.
Arnav Gupta, Sarah K Sasse, Margaret A Gruca, Lynn Sanford, Robin D Dowell

J Biol Chem· October 2021

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Genomic determinants implicated in the glucocorticoid-mediated induction of KLF9 in pulmonary epithelial cells.
Mahmoud M Mostafa, Akanksha Bansal, Aubrey N Michi, Sarah K Sasse, David Proud

J Biol Chem· September 2021

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Repression of transcription by the glucocorticoid receptor: A parsimonious model for the genomics era.
Anthony N Gerber, Robert Newton, Sarah K Sasse

J Biol Chem· July 2021

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The MUC5B-associated variant rs35705950 resides within an enhancer subject to lineage- and disease-dependent epigenetic remodeling.
Fabienne Gally, Sarah K Sasse, Jonathan S Kurche, Margaret A Gruca, Jonathan H Cardwell

JCI Insight· January 2021

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Angiogenic Potential of Bone Marrow Derived CD133 and CD271 Intramyocardial Stem Cell Trans- Plantation Post MI.
Sarah Sasse, Anna Skorska, Cornelia Aquilina Lux, Gustav Steinhoff, Robert David

Cells· December 2019

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Nascent transcript analysis of glucocorticoid crosstalk with TNF defines primary and cooperative inflammatory repression.
Sarah K Sasse, Margaret Gruca, Mary A Allen, Vineela Kadiyala, Tengyao Song

Genome Res· November 2019

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CD271 Human Mesenchymal Stem Cells Show Antiarrhythmic Effects in a Novel Murine Infarction Model.
Haval Sadraddin, Ralf Gaebel, Anna Skorska, Cornelia Aquilina Lux, Sarah Sasse

Cells· November 2019

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Old Cells in Young Airway Smooth Muscle: Does Neonatal Senescence Cause Lifelong Airway Obstruction?
Sarah K Sasse, Anthony N Gerber

Am J Respir Cell Mol Biol· July 2019

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Th1 cytokines TNF-α and IFN-γ promote corticosteroid resistance in developing human airway smooth muscle.
Rodney D Britt, Michael A Thompson, Sarah Sasse, Christina M Pabelick, Anthony N Gerber

Am J Physiol Lung Cell Mol Physiol· January 2019

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Long-Acting -Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)-Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR.
Christopher F Rider, Mohammed O Altonsy, Mahmoud M Mostafa, Suharsh V Shah, Sarah Sasse

Mol Pharmacol· September 2018

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Update in Natural Orifice Translumenal Endoscopic Surgery (NOTES).
Joern Bernhardt, Sarah Sasse, Kaja Ludwig, Peter N Meier

Curr Opin Gastroenterol· September 2017

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Mechanisms of stem cell based cardiac repair-gap junctional signaling promotes the cardiac lineage specification of mesenchymal stem cells.
Heiko Lemcke, Ralf Gaebel, Anna Skorska, Natalia Voronina, Cornelia Aquilina Lux, Sarah Sasse

Sci Rep· August 2017

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