Publications by authors named "Sarah Wazir"

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Discovery of 2-Amide-3-methylester Thiophenes that Target SARS-CoV-2 Mac1 and Repress Coronavirus Replication, Validating Mac1 as an Antiviral Target.
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff

J Med Chem· April 2024

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Discovery of 2-amide-3-methylester thiophenes that target SARS-CoV-2 Mac1 and repress coronavirus replication, validating Mac1 as an anti-viral target.
Sarah Wazir, Tomi A O Parviainen, Jessica J Pfannenstiel, Men Thi Hoai Duong, Daniel Cluff

bioRxiv· December 2023

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ABCG5/G8 Crystallization in a Lipidic Bicelle Environment for X-Ray Crystallography.
Sarah Wazir, Danny Farhat, Mahalashmi Srinivasan, Jyh-Yeuan Lee

J Vis Exp· August 2023

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Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain.
Lavinia M Sherrill, Elva E Joya, AnnMarie Walker, Anuradha Roy, Yousef M Alhammad, Sarah Wazir

Bioorg Med Chem· August 2022

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Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening.
Anu Roy, Yousef M Alhammad, Peter McDonald, David K Johnson, Junlin Zhuo, Sarah Wazir

Antiviral Res· July 2022

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Preparation of screening assays for ADP-ribosyl readers and erasers using the GAP-tag as a binding probe.
Sven T Sowa, Albert Galera-Prat, Sarah Wazir, Heli I Alanen, Mirko M Maksimainen

STAR Protoc· March 2022

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Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening.
Anu Roy, Yousef M Alhammad, Peter McDonald, David K Johnson, Junlin Zhuo, Sarah Wazir

bioRxiv· March 2022

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Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV2 nsp3 Macrodomain.
Lavinia M Sherrill, Elva E Joya, AnnMarie Walker, Anuradha Roy, Yousef M Alhammad, Sarah Wazir

bioRxiv· February 2022

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A molecular toolbox for ADP-ribosyl binding proteins.
Sven T Sowa, Albert Galera-Prat, Sarah Wazir, Heli I Alanen, Mirko M Maksimainen

Cell Rep Methods· December 2021

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Macrodomain Binding Compound MRS 2578 Inhibits Alphavirus Replication.
Sari Mattila, Pirjo Merilahti, Sarah Wazir, Tania Quirin, Mirko M Maksimainen

Antimicrob Agents Chemother· November 2021

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Activity-Based Screening Assay for Mono-ADP-Ribosylhydrolases.
Sarah Wazir, Mirko M Maksimainen, Heli I Alanen, Albert Galera-Prat, Lari Lehtiö

SLAS Discov· January 2021

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Multiple crystal forms of human MacroD2.
Sarah Wazir, Mirko M Maksimainen, Lari Lehtiö

Acta Crystallogr F Struct Biol Commun· October 2020

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